Int J Pharm Pharm Sci, Vol 8, Issue 5, 423Erratum
WOUND HEALING ACTIVITY OF FRUITS OF ANAMIRTA COCCULUS LINN IN RATS
V. SATYA*1, M. PARIDHAVI2
1*Dept. of Pharmacognosy, Karpagam University, Tamilnadu, 2Rajiv Gandhi Institute of Pharmacy, Meeliyat, Trikaripur, Kasaragod 670310, Kerala, India
Email: satyav72@gmail.com
Ref: tp:// www.ijppsjournal.com/Vol5Issue4/7587.pdf
ABSTRACT
Objective: The fruits of Anamirta Cocculus Linn are used traditionally in India for the treatment of bronchitis, chronic skin diseases, foul ulcers, dermatophytosis, phthisis, fungal infections, vertigo and vitiated conditions of vata & kapha. The purpose of the present study was to evaluate the wound healing activity of the ethanolic extract of its fruit in excision wound model.
Methods: Albino Wistar rats of either sex were divided into three groups, viz, wounded control, wounded rats administered standard drug Ciprofloxacin (2 %), and wounded rats administered A.C. 200 mg/kg, respectively. In excision wound model, wound contraction was studied.
Results: Increased wound contraction was observed in the extract-treated group when compared to control. Wound healing activity was statistically significant (p < 0.05) & (p < 0.001) in animals treated with 200 mg/kg of the extract.
Conclusion: The ethanolic extract of A. Cocculus possesses significant wound healing activity. Keywords: Anamirta Cocculus, Wound healing, Dermatophytosis, Wound model.
1) The article is entitled as “Wound healing activity of detoxified pericarp extract of fruits of Anamirta cocculus linn in rats.”
2) In present research detoxified pericarp extract of the Anamirta cocculus fruits was used for wound healing studies.
3) The pericarp extract contains only phytosterols but not alkaloids.