PHYTOCHEMICAL ANALYSIS OF RUELLIA PATULA USING GAS CHROMATOGRAPHY‑MASS SPECTROMETRY

Authors

  • Karthika C
  • Yogeshwari G
  • MURUGANANTHAM K
  • MANIVANNAN S Assistant Professor,PG and Research Department of Biotechnology,Bharath College of Science and Management,Thajavur - 613 005.Tamil Nadu, India

Abstract

ABSTRACT
Objective: Ruellia patula (Jacq.) a medicinally important plant belongs to the family Acanthaceae. Traditionally, the leaves are used in the treatment of
many diseases such as insect bites, itches, eye diseases, and skin problems. In the present study, the qualitative and quantitative analysis of bioactive
compounds by gas chromatography (GC) and mass spectroscopy (MS) techniques.
Methods: The chemical compositions of the ethanol extract of R. patula leaves were investigated using Perkin–Elmer GC‑MS.
Result: In the GC‑MS analysis of ethanol extract of R. patula L. reported the presence of 15 compounds. The major compound constituents are 3, 7, 11,
15‑tetramethyl‑2‑hexadecen‑1‑ol (28.75%), and α‑sitosterol (14.35%).
Conclusion: Identification of these compounds can help in the development of new drugs.
Keywords: Ruellia patula, Ethanol extract, Phytochemical compounds, gas chromatography‑mass spectroscopy analysis, Biological activity of
phyto‑components.

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Author Biography

Karthika C

YOGESHWARI G

References

REFERENCES

Mans DR. From forest to pharmacy: Plant‑based traditional medicines as

sources for novel therapeutic compounds. Acad J Med Plants 2013;1:101‑10.

Lev E. Ethno‑diversity within current ethno‑pharmacology as part of

Israeli traditional medicine – A review. J Ethnobiol Ethnomed 2006;2:4.

Facchini PJ. Alkaloid biosynthesis in plants: Biochemistry, cell biology,

molecular regulation, and metabolic engineering applications. Annu

Rev Plant Physiol Plant Mol Biol 2001;52:29‑66.

Goldman P. Herbal medicines today and the roots of modern

pharmacology. Ann Intern Med 2001;135:594‑600.

Firn RD, Jones CG. Natural products – A simple model to explain

chemical diversity. Nat Prod Rep 2003;20(4):382‑91.

Wink M. Evolution of secondary metabolites from an ecological and

molecular phylogenetic perspective. Phytochemistry 2003;64(1):3‑19.

Bhuvaneswari S, Manivannan S. Anti‑diabetic and anti‑inflammatory

activity of Carlluma adscendens var. Adscendens. Int J Pharm Bio Sci

;5:42‑9.

Gopalakrishnan S, Saroja K, Elizabeth JD. GC‑MS analysis of the

methanolic extract of the leaves of Dipteracanthus patulus (Jacq.)

Nees. Res J Chem Pharm 2011;3:477‑80.

Samy MN, Khalil HE, Sugimoto S, Matsunami K, Otsuka H, Kamel MS.

Three new flavonoid glycosides, byzantionoside B 6’‑O‑sulfate and

xyloglucoside of (Z)‑hex‑3‑en‑1‑ol from Ruellia patula. Chem Pharm

Bull (Tokyo) 2011;59(6):725‑9.

Akhtar MF, Rashid S, Ahmad M, Usmanghani K. Cardiovascular

evaluation of Ruellia patula and Ruellia brittoniana. J Islam Acad Sci

;5:67‑71.

Yadav S, Arya V, Kumar S, Yadav JP. Anti‑inflammatory activity of root,

leaves and stem of Dipteracanthus patulus (Jacq.) Nees (Acanthaceae).

Asian Pac J Trop Biomed 2012;2:187‑91.

Kannikaparameswari N, Chinnaswamy P. Identification and

quantification of Lupeol in Dipteracanthus patulus (Jacq.) Nees by

high performance liquid chromatography‑photo diode array method.

Int J Pharm Biol Sci 2013;4:660‑6.

Srikumar PP, Pardhasaradhi P. Preliminary phytochemical investigation

and anti‑ulcer activity of aerial parts of Ruellia tuberosa L. (Acanthaceae)

in male Wistat rats. Int J Pharm Biomed Res 2013;4:145‑8.

Kumari TK, Muthukumarasamy S, Mohan VR. GC‑MS analysis of

ethanol extract of Sarcostemma secamone L. Bennet (Asclepiadaceae).

Sci Res Rep 2012;2:187‑91.

Published

01-03-2016

How to Cite

C, K., Y. G, M. . K, and M. S. “PHYTOCHEMICAL ANALYSIS OF RUELLIA PATULA USING GAS CHROMATOGRAPHY‑MASS SPECTROMETRY”. Asian Journal of Pharmaceutical and Clinical Research, vol. 9, no. 2, Mar. 2016, pp. 111-3, https://journals.innovareacademics.in/index.php/ajpcr/article/view/10000.

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