PREVALENCE AND RISK FACTOR OF POLYCYSTIC OVARIAN SYNDROME

Authors

  • Shaiba Sana Qureshi
  • Jeetendra Kumar Gupta GLA University
  • Kamal Shah
  • Neeraj Upmanyu

Abstract

ABSTRACT
Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in women. Its clinical manifestation varies from mild to severe
disturbance of reproductive and metabolic functions. PCOS is clinical and public health importance because it is affecting up to one in five women
of reproductive age. It is an X-linked dominant condition and has diverse clinical implications such as psychological features (anxiety, depression),
reproductive features (hirsutism and hyperandrogenism), and impaired glucose tolerance. It is widely dependent on environmental, genetic, ethnicity
factors including lifestyle and body weight. Weight loss improves the endocrine profile and increases chances of ovulation and pregnancy. It can
be treated with medications such as clomiphene citrate, tamoxifen, aromatase inhibitors, and gonadotrophins. The last option for fertilization is
in vitro fertilization when other treatment fails. Its prevalence is estimated at 4-8% from studies performed in Spain and USA. Lifestyle including diet,
exercise, and behavior therapy improves fertility. PCOS has unique interactions with the ever increasing obesity prevalence worldwide as obesityinduced
insulin resistance
significantly
aggravates
all the
features
of PCOS.
Education
about
how
PCOS
affects
long-term
health should
be provided

to
women
with this disorder
to
feel
physical
and psychological
benefits so that they
could engage
themselves
more
with their health care
providers.
Keywords: Polycystic ovarian syndrome, Hyperinsulinemia, Hormone disbalance, Hirsutism, Ovarian cyst, Obesity, Sleep disorders.

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Author Biography

Jeetendra Kumar Gupta, GLA University

Division of Pharmacology, Assistant Professor

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Published

01-03-2016

How to Cite

Qureshi, S. S., J. K. Gupta, K. Shah, and N. Upmanyu. “PREVALENCE AND RISK FACTOR OF POLYCYSTIC OVARIAN SYNDROME”. Asian Journal of Pharmaceutical and Clinical Research, vol. 9, no. 2, Mar. 2016, pp. 23-25, https://journals.innovareacademics.in/index.php/ajpcr/article/view/10202.

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Review Article(s)