DYSLIPIDEMIA AMONG SMOKERS

Authors

  • Preeti Sharma Santosh University
  • Pradeep Kumar
  • Rachna Sharma
  • Kishor K
  • Gupta G

Abstract

ABSTRACT
Objective: The objective of this study is to evaluate lipid profile among cigarette smokers and compare it with non-smokers.
Methods: About 125 subjects aged between 20 and 40 years including 100 smokers as case group and 25 non-smokers as control were taken into
study. They did not having any history of any disease (i.e., diabetes, hypertension, liver diseases, renal diseases, or obesity) or alcohol intake. They
were not taking any drug such as B-blockers, lipid lowering drugs, or thiazide diuretics.
Results: The mean serum total cholesterol, low-density lipoprotein cholesterol (LDL-C), very LDL-C (VLDL-C) were significantly raised (p<0.05) in
all three groups of mild, moderate, and heavy smokers as compared to non-smokers control while mean serum high--density lipoproteins cholesterol
(HDL-C) was significantly lower in all three above said groups.
Conclusion: Cigarette/beedi smoking is associated with lower level of god cholesterol, i.e., HDL, and higher level of cholesterol, triglycerides, and
serum LDL and VLDL.
Keywords: Dyslipidemia, smokers

Downloads

Download data is not yet available.

Author Biography

Preeti Sharma, Santosh University

Professor of Biochemistry

References

REFERENCES

Altuntas I, Dane S, Gümüstekin K. Effects of cigarette smoking on lipid

peroxidation. J Basic Clin Physiol Pharmacol 2002;13(1):69-72.

Rao CS, Subash YE. The effect of chronic tobacco smoking and

chewing on the lipid profile. J Clin Diagn Res 2013;7(1):31-4.

Lakshmi SA, Lakshmanan A, Kumar PG, Saravanan A. Effect of

intensity of cigarette smoking on haematological and lipid parameters.

J Clin Diagn Res 2014;8(7):BC11-3.

Austin MA. Plasma triglyceride and coronary heart disease. Arterioscler

Thromb 1991;11:2-14.

Krishnaswami S, Richard J, Prasad NK, Alexander T, Thomas CS.

Association between cigarette smoking and coronary arterial disease

in patients in India: How quantitative is it? An assessment by selective

coronary arteriography. Int J Cardiol 1991;31(3):305-11.

Stamford BA, Matter S, Fell RD, Sady S, Papanek P, Cresanta M.

Cigarette smoking, exercise and high density lipoprotein cholesterol.

Atherosclerosis 1984;52(1):73-83.

Chelland Campbell S, Moffatt RJ, Stamford BA. Smoking and smoking

cessation -- The relationship between cardiovascular disease and

lipoprotein metabolism: A review. Atherosclerosis 2008;201(2):225-35.

Dhalla NS, Temsah RM, Netticadan T. Role of oxidative stress in

cardiovascular diseases. J Hypertens 2000;18(6):655-73.

Available from: http://www.spinreact.com/files/Inserts/Bioquimica/

BSIS11_COLEST._02-2014.pdf.

Friedewald WT, Levy RI, Fredrickson DS. Estimation of the

concentration of low-density lipoprotein cholesterol in plasma, without

use of the preparative ultracentrifuge. Clin Chem 1972;18(6):499-502.

McGowan MW, Artiss JD, Strandbergh DR, Zak B. A peroxidasecoupled

method for the colorimetric

determination of

serum

triglycerides.

Clin Chem 1983;29(3):538-42.

Trinder P. Determination of blood glucose using an oxidase– peroxidase

system with a non-carcinogenic chromogen. Ann Clin Biochem

;6:24-30.

Adedeji OA, Etukudo MH. Lipid profile of cigarette smokers in Calabar

municipality. Pak J Nutr 2006;5(30):237-38.

Ayaori M, Hisa T, Suzukawa M, Yoshida H, Nishiwaki M, Ito T,

et al Plasma level and redox status of ascorbic acid and level of lipid

peroxidation product in active and passive smokers. Environ Health

Perspect 2000;108(2):105-8.

Neki NS. Lipid profile in chronic smokers - A clinical study. Indian

Acad Clin Med 2005;3(1):51-4.

Jaleel A, Jaleel F, Majeed R, Alam E. Leptin and blood lipid level in

smokers and ex smokers. World Appl Sci J 2007;2(4):248-352.

Published

01-07-2016

How to Cite

Sharma, P., P. Kumar, R. Sharma, K. K, and G. G. “DYSLIPIDEMIA AMONG SMOKERS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 9, no. 4, July 2016, pp. 137-8, https://journals.innovareacademics.in/index.php/ajpcr/article/view/11798.

Issue

Section

Original Article(s)

Most read articles by the same author(s)

1 2 3 > >>