EFFECT OF SMOKING ON HEART RATE VARIABILITY IN NORMAL HEALTHY VOLUNTEERS

Authors

  • Samuel Sundar Doss D saveetha medical college and hospital
  • Anandhalakshmi S
  • Rekha K
  • Akhil Antony K

Abstract

ABSTRACT
Objective: The aim of this study is to determine the effect of tobacco smoke on heart rate variability (HRV).
Methods: This study included 90 male smokers (30-mild, 30-moderate, 30-severe) (Group II) and 30 age-matched non-smokers as controls (Group I).
HRV analysis was performed using 8 channels Physiopac of Medicaid Company. All the subjects were subjected to HRV test. The short-term 8 minutes
HR recording was performed for HRV analysis.
Results: Mean RR, mean HR, root mean square of the successive differences, of the smokers and non-smokers, did not differ significantly. However,
smokers NN50, Pnn50, high frequency (HF) declined significantly, and the smokers show significantly higher low frequency (LF), LF/HF ratio when
compared with those of the non-smoking individuals (p<0.05).
Conclusion: HRV analysis of smokers and nonsmokers showed that smoking subjects had an autonomic imbalance suggestive of an increased
sympathetic tone or decreased parasympathetic tone. Sympathetic overactivity may lead to cardiovascular disease development in smokers.
Keywords: Smoking, Healthy volunteers, Heart rate variability.

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References

REFERENCES

Chhabra SK, Rajpal S, Gupta R. Patterns of smoking in Delhi and

comparison of chronic respiratory morbidity among beedi and cigarette

smokers. Indian J Chest Dis Allied Sci 2001;43(1):19-26.

WHO Report. Tobacco could kill one billion by 2100. Sci Daily

;24:71.

Kumar R, Prakash S, Kushwah AS, Vijayan VK. Breath carbon

Asian J Pharm Clin Res, Vol 9, Issue 4, 2016, 230-234

Doss et al.

monoxide concentration in cigarette and bidi smokers in India. Indian J

Chest Dis Allied Sci 2010;52(1):19-24.

World Health Organization. Tobacco Free Initiative. Kobe, Japan:

Tobacco Product Regulation Group; 2006.

US Department of Health and Human Services. The Health

Consequences of Smoking: Nicotine Addiction. A Report of the

Surgeon General. Atlanta, Georgia: US Department of Health and

Human Services, Public Health Service, Centers for Disease Control,

Center for Health Promotion and Education, Office on Smoking and

Health; 1988.

Villablanca AC, McDonald JM, Rutledge JC. Smoking and

cardiovascular disease. Clin Chest Med 2000;21(1):159-72.

US Department of Health and Human Services. The Health

Consequences of Smoking: Cardiovascular Disease. A Report of the

Surgeon General. Rockville, Maryland: Public Health Service, Office

on Smoking and Health; 1983.

Willett WC, Green A, Stampfer MJ, Speizer FE, Colditz GA, Rosner B,

et al. Relative and absolute excess risks of coronary heart disease among

women who smoke cigarettes. N Engl J Med 1987;317(21):1303-9.

Rosenfeld JA. Heart disease in women. Gender-specific statistics

and prevention strategies for a population at risk. Postgrad Med

;107(6):111-6.

Huikuri HV, Mäkikallio T, Airaksinen KE, Mitrani R, Castellanos A,

Myerburg RJ. Measurement of heart rate variability: A clinical tool or a

research toy? J Am Coll Cardiol 1999;34(7):1878-83.

Karakaya O, Barutcu I, Kaya D, Esen AM, Saglam M, Melek M, et al.

Acute effect of cigarette smoking on heart rate variability. Angiology

;58(5):620-4.

Barutcu I, Esen AM, Kaya D, Turkmen M, Karakaya O, Melek M,

et al. Cigarette smoking and heart rate variability: Dynamic influence

of parasympathetic and sympathetic maneuvers. Ann Noninvasive

Electrocardiol 2005;10(3):324-9.

Manzano BM, Vanderlei LC, Ramos EM, Ramos D. Acute effects of

smoking on autonomic modulation: Analysis by Poincaré plot. Arq

Bras Cardiol 2011;96(2):154-60.

Kobayashi F, Watanabe T, Akamatsu Y, Furui H, Tomita T,

Ohashi R, et al. Acute effects of cigarette smoking on the heart rate

variability of taxi drivers during work. Scand J Work Environ Health

;31(5):360-6.

Subramaniam BS. Influence of body mass index on heart rate variability

in evaluating cardiac function in adolescents of a selected Indian

population. Ital J Public Health 2011;8(2):149-55.

Kamath MV, Ghista DN, Fallen EL, Fitchett D, Miller D, McKelvie R.

Heart rate variability power spectrogram as a potential non-invasive

signature of cardiac regulatory system response, mechanisms and

disorders. Heart Vessels 1987;3(1):33-41.

Published

01-07-2016

How to Cite

Doss D, S. S., A. S, R. K, and A. A. K. “EFFECT OF SMOKING ON HEART RATE VARIABILITY IN NORMAL HEALTHY VOLUNTEERS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 9, no. 4, July 2016, pp. 230-4, https://journals.innovareacademics.in/index.php/ajpcr/article/view/12031.

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