CHALLENGES IN THE MANAGEMENT OF BRONCHIOLITIS

Authors

  • Pumbi Shalini Kumari MALLA REDDY COLLEGE OF PHARMACY, AFFILIATED TO OSMANIA UNIVERSITY
  • Syeda Shafia

Abstract

ABSTRACT
Objective: This study aims to review and evaluate current medication and to provide practical guidelines to the practitioners managing children with
bronchiolitis.
Methods: A 6-month retrospective study was carried out in the Department of Paediatrics in Tertiary Care Hospital, a 350-bedded multispecialty
hospital to review the management of bronchiolitis. A total of 60 cases selected from July 2014 to December 2014 were included in the study. Patient
data and prescription details were recorded and analyzed accordingly.
Results: About 58.3% of bronchiolitis cases were reported in the age group of <1 year, 26.6% in the age group of 1-2 years and 15% cases
reported at the age >2 years. Commonly reported symptoms in different cases include 85% of cases with fever, 90% with a cough, 93.3% with
cold, 30% with vomiting, 35% with breathlessness, 33.3% with loose motions, and 68.3% with wheezing. A single broad-spectrum antibiotic
was used in 68.3% cases, two broad spectrum antibiotics in 26.6% of cases, and three or more combinations in 5% of cases to prevent bacterial
coinfections. A careful assessment of study has evaluated that antiviral therapy was not used in any of the cases to avoid antiviral resistance
but broad-spectrum antibiotics were most commonly prescribed for a viral respiratory illness which is generally self-limiting adding to the
threat of antibiotic resistance. Bronchodilators and corticosteroids were routinely used. As per current Standard Treatment Guidelines for the
management of bronchiolitis, the priority has been given to adequate rest, intravenous fluids, symptomatic therapy, and reserve antiviral therapy
for special cases. This study demonstrated the importance of routine medication review and the need of a clinical pharmacist at various levels
of clinical setup.
Conclusion: From this study, it can be concluded that interventions by a clinical pharmacist are needed in taking a special effort to analyze prescriptions
and provide clinicians with a feedback involving available antiviral medications, antiviral resistance, prescription costs, limitations of antiviral agents
and updated current standard treatment guidelines.
Keywords: Self-limiting, Antiviral therapy, Antiviral resistance, Antibiotic use, Antibiotic resistance.

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Author Biography

Pumbi Shalini Kumari, MALLA REDDY COLLEGE OF PHARMACY, AFFILIATED TO OSMANIA UNIVERSITY

Pharm D

References

REFERENCES

Verma N, Lodha R, Kabra SK. Recent advances in management of

bronchiolitis. Indian Pediatr 2013;50(10):939-49.

American Academy of Pediatrics Subcommittee on Diagnosis

and Management of Bronchiolitis. Diagnosis and management of

bronchiolitis. Pediatrics 2006;118(4):1774-93.

Hanson IC, Shearer WT. Bronchiolitis. In: McMillan JA, Feign RD,

De Angelis C, Jones MD, editors. Oski’s Pediatrics: Principles and

Practice. 4

ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2006.

p. 1391.

th

Wright AL, Tausig LM, Ray CG, Harrison HR, Holberg CJ.

The Tucson children’s respiratory study. II. Lower respiratory

tract illness in the first year of life. Am J Epidemiol

;129(6):1232-46.

Flaherman VJ, Ragins AI, Li SX, Kipnis P, Masaquel A, Escobar GJ.

Frequency, duration and predictors of bronchiolitis episodes of care

among infants ≥32weeks gestation in a large integrated healthcare

system: A retrospective cohort study. BMC Health Serv Res

Asian J Pharm Clin Res, Vol 9, Issue 4, 2016, 281-283

Kumari et al.

;12:144.

Markopoulou KD, Cool CD, Elliot TL, Lynch DA,

Newell JD, Hale VA, et al. Obliterative bronchiolitis: Varying

presentations and clinicopathological correlation. Eur Respir J

;19(1):20-30.

King VJ, Viswanathan M, Bordley WC, Jackman AM, Sutton SF,

Kathleen BS. Pharmacologic treatment of bronchiolitis in infants and

children. Arch Pediatr Adolesc Med 2004;158(2):127-37.

Published

01-07-2016

How to Cite

Pumbi Shalini Kumari, and S. Shafia. “CHALLENGES IN THE MANAGEMENT OF BRONCHIOLITIS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 9, no. 4, July 2016, pp. 281-3, https://journals.innovareacademics.in/index.php/ajpcr/article/view/12151.

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Original Article(s)