Pattern of medication use among elderly patients attending medicine department in a tertiary care hospital in India
DOI:
https://doi.org/10.22159/ajpcr.2016.v9i6.14368Abstract
Objective: The present study was aimed to assess the drug prescribing pattern and analyze the prescribing pattern using Beers criteria among elderly patients aged over 60 years Materials and Methods: The present study was a prospective observational study conducted in the outpatient department of general medicine in a tertiary care hospital for the duration of three months. Institutional ethics committee approval was taken prior to initiation of the study. Written informed consent was taken from each study subject. A total of 287 subjects who were aged more than 60 years recruited into the study. The data was collected in a pre structured case record form. Subjects' demographic details, medical conditions and drugs included in prescription their dose; frequency and duration were noted in case record form. Results: Among 287 subjects 91.64% subjects belonged to 61-70years age group, remaining 8.36% subjects were >71year older and 57.14% were males and 42.86% were females. Hypertension was the most common cause of attending hospital followed by diabetes mellitus, CNS disorders, respiratory, cardiovascular disorders other than hypertension and infectious diseases. A total of 1574 formulations containing 1669 active ingredients and 90 FDCs were prescribed. And only 152 formulations were prescribed from outside hospital formulary. The average number of drugs per prescription was 5.48±2.00. Among the individual drugs vitamin B complex was the most commonly prescribed drug Conclusion:  There is need for more rational prescribing and to form guidelines for safe and effective use of medicines in elderly patients.
Downloads
References
REFERENCES
United Nations. World Population Prospects: The 2010 Revision.
Available from: http://www.un.org/en/development/desa/
population/publications/pdf/trends/WPP2010/WPP2010_Volume-I_
Comprehensive-Tables.pdf. [Last accessed on 2016 May 30].
Situation Analysis of Elderly in India Central Statistics Office, June;
Available from: http://www.mospi.nic.in/mospi_new/upload/
elderly_in_india.pdf. [Last accessed on 2016 May 30].
McLean AJ, Le Couteur DG. Aging biology and geriatric clinical
pharmacology. Pharmacol Rev 2004;56(2):163-84.
Hajjar ER, Cafiero AC, Hanlon JT. Polypharmacy in elderly patients.
Am J Geriatr Pharmacother 2007;5(4):345-51.
Kennerfalk A, Ruigómez A, Wallander MA, Wilhelmsen L,
Johansson S. Geriatric drug therapy and healthcare utilization in the
United kingdom. Ann Pharmacother 2002;36(5):797-803.
Gallagher P, Barry P, O’Mahony D. Inappropriate prescribing in the
elderly. J Clin Pharm Ther 2007;32(2):113-21.
Routledge PA, O’Mahony MS, Woodhouse KW. Adverse drug reactions
in elderly patients. Br J Clin Pharmacol 2004;57(2):121-6.
Seymour RM, Routledge PA. Important drug-drug interactions in the
elderly. Drugs Aging 1998;12(6):485-94.
Dormann H, Sonst A, Müller F, Vogler R, Patapovas A, Pfistermeister B,
et al. Adverse drug events in older patients admitted as an emergency:
The role of potentially inappropriate medication in elderly people
(PRISCUS). Dtsch Arztebl Int 2013;110(13):213-9.
World Health Organization. Introduction to Drug Utilization Research.
Geneva: World Health Organization; 2003.
Beers MH. Explicit criteria for determining potentially inappropriate
medication use by the elderly. An update. Arch Intern Med
;157(14):1531-6.
American Geriatrics Society 2012 Beers Criteria Update Expert Panel.
American geriatrics society updated beers criteria for potentially
inappropriate medication use in older adults. J Am Geriatr Soc
;60(4):616-31.
Delgado Silveira E, Montero Errasquin B, Munoz Garcia M,
Velez-Diaz-Pallares M, Lozano Montoya I, Sanchez-Castellano C,
et al. Improving drug prescribing in the elderly: A new edition of
STOPP/START criteria. Rev Esp Geriatr Gerontol 2014 22. pii: S0211-
X(14)00223-6.
Ubeda A, Ferrándiz L, Maicas N, Gomez C, Bonet M, Peris JE.
Potentially inappropriate prescribing in institutionalised older patients
in Spain: The STOPP-START criteria compared with the beers criteria.
Pharm Pract (Granada) 2012;10(2):83-91.
Available from: http://www.who-umc.org/Graphics/24734.pdf. [Last
accessed on 2016 May 30].
Harugeri A, Joseph J, Parthasarathi G, Ramesh M, Guido S.
Potentially inappropriate medication use in elderly patients: A study of
prevalence and predictors in two teaching hospitals. J Postgrad Med
;56(3):186-91.
Fadare JO, Agboola SM, Opeke OA, Alabi RA. Prescription pattern
and prevalence of potentially inappropriate medications among elderly
patients in a Nigerian rural tertiary hospital. Ther Clin Risk Manag
;9:115-20.
Jhaveri BN, Patel TK, Barvaliya MJ, Tripathi CB. Drug utilization
pattern and pharmacoeconomic analysis in geriatric medical inpatients
of a tertiary care hospital of India. J Pharmacol Pharmacother
;5(1):15-20.
Doubova Dubova SV, Reyes-Morales H, Torres-Arreola Ldel P,
Suárez-Ortega M. Potential drug-drug and drug-disease interactions in
prescriptions for ambulatory patients over 50 years of age in family
medicine clinics in Mexico City. BMC Health Serv Res 2007;7:147.
Shah RB, Gajjar BM, Desai SV. Drug utilization pattern among
geriatric patients assessed with the anatomical therapeutic chemical
classification/defined daily dose system in a rural tertiary care teaching
hospital. Int J Nutr Pharmacol Neurol Dis 2012;2:258-65.
Maher RL, Hanlon J, Hajjar ER. Clinical consequences of polypharmacy
in elderly. Expert Opin Drug Saf 2014;13(1):57-65.
Jolivot PA, Pichereau C, Hindlet P, Hejblum G, Bigé N, Maury E, et al.
An observational study of adult admissions to a medical ICU due to
adverse drug events. Ann Intensive Care 2016;6(1):9.
Mohd AH, Mateti UV, Konuru V, Parmar MY, Kunduru BR. A study on
prescribing patterns of antihypertensives in geriatric patients. Perspect
Clin Res 2012;3(4):139-42.
Agarwal AA, Jadhav PR, Deshmukh YA. Prescribing pattern and
efficacy of anti-diabetic drugs in maintaining optimal glycemic levels
in diabetic patients. J Basic Clin Pharm 2014;5(3):79-83.
Pathak S, Singh L, Singh T, Sharma SK. Prescribing patterns of antiepileptic
drug in different age group in India. J Drug Discov Ther
;1(7):69-75.
Published
How to Cite
Issue
Section
The publication is licensed under CC By and is open access. Copyright is with author and allowed to retain publishing rights without restrictions.