A Prospective study on the assessment of risk factors for type 2 diabetes mellitus in outpatients department of a south Indian tertiary care hospital: A case-control study

Authors

  • SIVAPRASAD PENDYALA
  • SIDDHARTHA NUTHAKKI
  • CHARAN VALLABHU
  • NAVEENBABU KILARU
  • SIVA R CHALLA
  • Ravindrababu Pingili

DOI:

https://doi.org/10.22159/ajpcr.2016.v9i6.14427

Abstract

Background: Type 2 diabetes mellitus (T2DM) is the most general type of diabetes. In India, the risk factors (modifiable and nonmodifiable) for diabetes are seen more frequently and there is lack of perception about this problem.

Objective: The objective of the study was to assess the incidence and risk factors for T2DM in a south Indian tertiary care hospital.

Materials and Methods: A prospective study was conducted on 1161 subjects (with or without T2DM) from November 2014 to April 2015 in general medicine department of Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation, Andhra Pradesh, south India. Chi-square test was used to evaluate the incidence of T2DM and odds ratios were calculated in univariate logistic regression analysis for risk factors.

Results: T2DM was significantly higher in the subjects of age above 41 years (86.3%, P<0.0001), married (95.4%, P=0.002), educators (degree and above, 13.2%, P<0.0001), known family history (50.8%, P<0.0001), BMI (>25 kg/m2,58.7%; P<0.0001), Govt. job holders (5.5%, P<0.0001), business people (12%, P<0.0001), house wives (38.3%, P<0.0001), high economic status (34.9%, P<0.0004), preexisting hypertension (40.2%, P<0.0001), urban residence (50.4%, P<0.0001), physical inactivity (45.3%, P<0.001), stress (61.0%, P=0.01), consumption of tea and coffee (daily thrice or more, 6.3%, P=0.0003), soft drinks (weekly thrice or more, 4%, P=0.0008) and junk foods (weekly thrice or more 2.6%, P=0.025) than non-diabetic subjects. Univariate logistic regression analysis showed that the age (above 41 years), marital status, education, family history, BMI (>25 kg/m2), high economic status, co-morbidities (hypertension and thyroid disorders) urban residence, physical inactivity, stress, consumption of tea and coffee (daily thrice or more), soft drinks (weekly thrice or more) and junk foods are the significantly risk factors for T2DM.

Conclusion: The present study results suggested that beware of hypertension, thyroids disorders, physical inactivity, stress, soft drinks and junk foods, which are major risk factors of T2DM. 

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References

Manal AM, Samia SA, RahilaIftikhar and Bayan KS. Assessment of the Common Risk Factors Associated with Type 2 Diabetes Mellitus in Jeddah. Int J Endocrinol 2014; Article ID 616145: 9 pages.

Ravikumar P, Bhansali A, Ravikiran M et al. Prevalence and risk factors of diabetes in a community-based study in North India: The Chandigarh Urban Diabetes Study (CUDS). Diabetes Metab Rev 2011; 37: 216–221.

Salwa SIA, Ayman SA. A study evaluating prevalence of hypertension and risk factors affecting on blood pressure control among type 2 diabetes patients attending teaching hospital in Malaysia. Diabetes & Metabolic Syndrome: Clinical Research & Reviews 2013; 7: 83–86.

Viswanathan M, Prashant M, Raj D et al. Urban rural differences in prevalence of self-reported diabetes in India—The WHO–ICMR Indian NCD risk factor surveillance. . Diabetes Res Clin Pract 2008; 80: 159-168.

Feng N, Zengchang P, Tiina L. For Qingdao 2006 Diabetes Survey and FINRISK 2002 Study. Joint Effect of Family History of Diabetes with Obesity on Prevalence of Type 2 Diabetes Mellitus among Chinese and Finnish Men and Women. Can J Diabetes 2013; 37: 65-71.

Sanz C, Gautier JF, Hanaire H. Physical exercise for the prevention and treatment of type 2 diabetes. Diabetes Metab Rev 2010; 36: 346–351.

Brian KA, Pamala AJ, Robin LC, Wayne AK, Michael EE, Bradley RW and Joseph BG. Koda-Kimble and Young’s applied therapeutics: The clinical use of drugs. Tenth edition. Lippincott Williams & Wilkins-Wolters Kluwer, Philadelphia, United States of America.2013; Pg no: 1223-1300.

Abdul HZ, Abdul AW, Bashir AL et al. Prevalence of diabetes mellitus and other abnormalities of glucose tolerance in young adults aged 20–40 years in North India (Kashmir Valley). . Diabetes Res Clin Pract 2008; 82: 276-281.

Sheikh MSI, Dewan SA, Mohammed W et al. Clinical characteristics and complications of patients with type 2 diabetes attending an urban hospital in Bangladesh. Diabetes Metab Syndr: Clinical Research & Reviews 2015; 9: 7–13.

Gupta R, Misra A. Type 2 diabetes in India: Regional disparities. Br J Diabetes Vasc Dis. 2007; 7: 12-16.

Joshi SR et al. Challenges in diabetes care in India: sheer numbers, lack of awareness and inadequate control. J Assoc Physicians India. 2008; 56: 443-450.

Shivananda BN, Arianne S, Khalil L, Danielle P, Akash R, Kodi L, Nichole S. The association of age, gender, ethnicity, family history, obesity and Hypertension with type 2 diabetes mellitus in Trinidad. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 2014; 8: 91-95.

Fahad JS, Bilal IA, Sadia M, Debra JN, Abdul J, Pryseley NA. Uncontrolled diabetes mellitus: Prevalence and risk factors among people with type 2 diabetes mellitus in an Urban District of Karachi, Pakistan. Diabetes Research And Clinical Practice 2015: 107; 148-156.

Ravikumar P, Bhansali A, Ravikiran M, Bhansali S, Walia R, Shanmugasundar G, Thakur JS, Kumar SB, Dutta P. Prevalence and risk factors of diabetes in a community-based study in North India: The Chandigarh Urban Diabetes Study (CUDS). Diabetes & Metabolism 2011; 37: 216–221.

Nandimath VA, Swamy CS, Nandimath SA, Jatti G, Jadhav S. Evaluation of certain risk factors of type 2 diabetes mellitus: a case–control study. Int J Med Sci Public Health 2016;5:1334-1339

Ivan D, Marina S, Massimo MB, Dominique S, Iakov P, Gagik G. Prevalence of type 2 diabetes mellitus (T2DM) in the adult Russian population (NATION study). diabetes research and clinical practice 2016; 115: 90 – 95.

Lee DS, Kim YJ, Han HR. Sex differences in the association between socioeconomic status and type 2 diabetes: data from the 2005 Korean National Health and Nutritional Examination Survey (KNHANES). Public health. 2013; 127: 554-560.

Tonstad S, Stewar K, Batech M, Herring RP, Fraser GE. Vegetarian diets and incidence of diabetes in the Adventist Health Study-2. Nutrition, Metabolism & Cardiovascular Diseases. 2013; 23: 292-299.

Sanz C, Gautier JF, Hanaire H. Physical exercise for the prevention and treatment of type 2 diabetes. Diabetes & Metabolism 2010; 36: 346–351.

Christy C, Kathleen B, Nahla H, Shaï¬ka A, Abla MS. Prevalence, correlates and management of type 2 diabetes mellitus in Lebanon: Findings from a national population-based study diabetes research and clinical practice 2014; 105: 408 – 415.

Jacqueline R, Sudaba M, Mary M, Stewart BH, Bernard Z, Joel G, Thomas MSW, Phillip WC, Anthony H. Dietary Patterns and Type 2 Diabetes Mellitus in a First Nations Community. Can J Diabetes 2016;1-7.

Ehab SE, Hiroyasu I, Tetsuya M, Manami I, Mitsuhiko N, Shoichiro T. Soft drink, 100% fruit juice, and vegetable juice intakes and risk of diabetes mellitus. Clinical Nutrition 2013; 32: 300-308.

Rob MD, Edith JMF. Coffee consumption and risk of type 2 diabetes mellitus. Lancet 2002; 360: 1477–1478.

Published

01-11-2016

How to Cite

SIVAPRASAD PENDYALA, SIDDHARTHA NUTHAKKI, CHARAN VALLABHU, NAVEENBABU KILARU, SIVA R CHALLA, and R. Pingili. “A Prospective Study on the Assessment of Risk Factors for Type 2 Diabetes Mellitus in Outpatients Department of a South Indian Tertiary Care Hospital: A Case-Control Study”. Asian Journal of Pharmaceutical and Clinical Research, vol. 9, no. 6, Nov. 2016, pp. 300-4, doi:10.22159/ajpcr.2016.v9i6.14427.

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