EVALUATION OF KNOWLEDGE, AWARENESS, AND PRACTICE OF PHARMACOVIGILANCE AMONG PRACTICING DOCTORS
DOI:
https://doi.org/10.22159/ajpcr.2016.v9s3.14770Abstract
ABSTRACT
Objective: The primary objective of the study was to assess the awareness, knowledge, and practice of pharmacovigilance (PV) among the practicing
doctors. The secondary objective was to ascertain the reason for underreporting of adverse drug reactions (ADRs) in India.
Methods: A cross-sectional study was conducted using a pretested and validated questionnaire. The questionnaire was designed to assess these
parameters of PV. These questionnaires were distributed among 90 doctors to ascertain the answers. In addition, the same parameters were
reassessed (post-questionnaires) after sensitizing the doctors about PV.
Results: Only 52 doctors took the posttest, a response rate of 57%. The mean awareness, knowledge, and practice of PV among doctors were 4.70,
3.60, and 2.90, respectively, which significantly increased in post-test questionnaire (p<0.05). The Pearson correlations revealed that the level of
awareness among the respondents was significantly related to the knowledge and the practice of PV, linearly, and positively. In other words, higher the
awareness more was the knowledge and better was the methods of application. The most common factor discouraging doctors from reporting ADRs
was they found it difficult to decide whether ADR has occurred or not (32.69%).
Conclusion: There was a significant positive correlation between awareness, knowledge, and practice of PV. In spite of these findings, the ADR
reporting rate is negligible in India. To bring about a strong culture of reporting among doctors, it is mandatory to continuously expose doctors to the
concepts of PV by continuous medical education, workshops, seminars and to make reporting mandatory in India.
Keywords: Pharmacovigilance, Adverse drugs reactions, Awareness, Knowledge, Practice.
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References
WHO. International Drug Monitoring: The Role of National Centers. Report No, 498. Geneva, Switzerland: World Health Organization; 1972.
Joshi SR, Sapatnekar SM. Pharmacovigilance in India: How safe are the new drugs? How safe are we? J Assoc Physicians India 2008;56:933-4.
Ravi V. Re-emergence of chikungunya virus in India. Indian J Med Microbiol 2006;24:83-4.
Kamath S, Das AK, Parikh FS. Chikungunya. J Assoc Physicians India 2006;54:725-6.
Robert HB Jr, Jerry RM. Muscular dystrophies and other muscle diseases. In: Harrison’s, Principles of Internal Medicine. 16th ed., Vol. II. USA: McGraw hill, Medical Publishing Division; 2005. p. 2536.
The Importance of Pharmacovigilance. Geneva: WHO; 2002. Available from: http://www.apps.who.int/medicinedocs/pdf/s4893e/s4893e.pdf.
Kumari S, Saxena A, Senthilkumar P. Evaluation of knowledge, awareness and attitude practice among nurses in pharmacovigilance at tertiary care hospital in Delhi. J Harmo Res Phar 2015;4(1):76-86.
Lokesh K. Pharmacovigilance/reporting adverse drug reactions: An approach to enhance health surveillance and extending market share by minimizing the chances of drug withdrawals. Int J Pharm Pharm Sci 2015;7(9):1-7.
Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalised patients: A meta-analysis of prospective studies. J Am Med Assoc 1998;279:1200-5.
The National Pharmacovigilance Protocol, Ministry of Health and Family Welfare, Government of India. Available from: http://www.panacea-biotech.com/medicalzone/National%20 Pharmacovigilance % 20 Protocol. pdf.
Feely J, Moriarty S, O’Connor P. Stimulating the reporting of an ad verse drug reaction by using a fee. Br Med J 1990;300:22-3.
Hema NG, Bhuvana KB, Sangeetha. Pharmacovigilance: The extent of awareness among the final year students, interns and postgraduates in a government teaching hospital. J Clin Diagn Res 2012;6(7):1248-53.
Sivadasan S, Sellappan M. A study on the awareness and attitude towards pharmacovigilance and adverse drug reaction reporting among nursing students in a private university, Malaysia. Int J Curr Pharm Res 2015;7(1):84-9.
Inman WH. The attitudes to the adverse drug-reaction reporting. Br J Clin Pharmacol 1996;41:433-5.
Hardeep JK, Rakesh K. A survey on the knowledge, attitude and the practice of pharmacovigilance among the health care professionals in a teaching hospital in northern India. J Clin Diagn Res 2013;7(1):97-9.
Gupta SK, Roopa PN, Shivaranjani R, Vidyarthi SK. A questionnaire study on the knowledge, attitude, and the practice of pharmacovigilance among the healthcare professionals in a teaching hospital in South India. Perspect Clin Res 2015;6(1):45-52.
Khurana A, Rastogi R, Gamperl HJ. A new era of drug safety - new eu pharmacovigilance (PV) legislation and comparison of PV in EU, US and India. Int J Pharm Pharm Sci 2014;6(7):15-21.
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