STUDIES ON BIOACTIVE POTENTIAL OF STREPTOMYCES SPP. (KX710212). ISOLATED FROM ENVIRONMENTAL POLLUTED SAMPLE, RANIPET, VELLORE, INDIA

Authors

  • Henita Geo N
  • Panneerselvam A

DOI:

https://doi.org/10.22159/ajpcr.2016.v9s3.14788

Abstract

ABSTRACT
Objective: Natural products from bacterial origin played and still play a valuable role in drug discovery and provide diverse health-promoting
compounds that help to cure or alleviate serious diseases.
Methods: A total of 4 actinobacterial strains were isolated from 2 different environmental polluted soil samples collected from Ranipet, Vellore, Tamil
Nadu, India. Of 15 isolates screened for antibacterial property, 4 isolates (PS1, PS2, and PS3) were found potent and characterized phenotypically and
genotypically.
Results: The 16S rDNA gene sequences of potent strain showed 97% similarity with Streptomyces spp. and termed as Streptomyces sp. The bioactivity
was revealed by antibacterial and antioxidant activity.
Conclusion: Hence, these findings provide scientific evidence to validate the pharmacological use and have the potential contribution in the discovery
of new lead that play a key role in the field of therapeutics.
Keywords: Actinomycetes, Bioactive compounds, Antibacterial property.

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Published

01-12-2016

How to Cite

Geo N, H., and P. A. “STUDIES ON BIOACTIVE POTENTIAL OF STREPTOMYCES SPP. (KX710212). ISOLATED FROM ENVIRONMENTAL POLLUTED SAMPLE, RANIPET, VELLORE, INDIA”. Asian Journal of Pharmaceutical and Clinical Research, vol. 9, no. 9, Dec. 2016, pp. 356-9, doi:10.22159/ajpcr.2016.v9s3.14788.

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