STUDIES ON BIOACTIVE POTENTIAL OF STREPTOMYCES SPP. (KX710212). ISOLATED FROM ENVIRONMENTAL POLLUTED SAMPLE, RANIPET, VELLORE, INDIA
DOI:
https://doi.org/10.22159/ajpcr.2016.v9s3.14788Abstract
ABSTRACT
Objective: Natural products from bacterial origin played and still play a valuable role in drug discovery and provide diverse health-promoting
compounds that help to cure or alleviate serious diseases.
Methods: A total of 4 actinobacterial strains were isolated from 2 different environmental polluted soil samples collected from Ranipet, Vellore, Tamil
Nadu, India. Of 15 isolates screened for antibacterial property, 4 isolates (PS1, PS2, and PS3) were found potent and characterized phenotypically and
genotypically.
Results: The 16S rDNA gene sequences of potent strain showed 97% similarity with Streptomyces spp. and termed as Streptomyces sp. The bioactivity
was revealed by antibacterial and antioxidant activity.
Conclusion: Hence, these findings provide scientific evidence to validate the pharmacological use and have the potential contribution in the discovery
of new lead that play a key role in the field of therapeutics.
Keywords: Actinomycetes, Bioactive compounds, Antibacterial property.
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