TO STUDY THE DRUG USE PATTERN IN PRIMARY OPEN ANGLE GLAUCOMA IN A TERTIARY CARE TEACHING
DOI:
https://doi.org/10.22159/ajpcr.2017.v10i2.15172Abstract
Objective: To study the drug utilization pattern in patients suffering from primary open-angle glaucoma (POAG) in a tertiary care teaching hospital.
Methods: It is a prospective study done on 50 patients of POAG (comprising of individuals belonging to any age group). This study was carried for a period of 2-month, and the data included patient's demographic details and the drugs prescribed. Data were analyzed for drug use pattern.
Results: After screening the prescriptions of patients, it was found out that out of total 50 prescriptions, 30 were males, and 20 were females. Out of
50 prescriptions, prostaglandins (58%) were most commonly prescribed. β-blockers (16%) were also prescribed. Fixed dose combination constituted
60% of the prescriptions. Instructions about the route, frequency, and duration of treatment were present in all prescriptions. Drugs prescribed by their generic names were 18.75% and about 81.25% of the drugs were prescribed by their brand names.
Conclusions: Fixed drug combination of timolol and dorzolamide was the most frequently prescribed combination. Prescribers must be aware of
importance of prescribing drugs with generic names.
Keywords: Primary open-angle glaucoma, Intraocular pressure, Fixed dose combination.
Downloads
References
Yadav AK, Patel V. Drug use in primary open angle glaucoma: A
prospective study at a tertiary care teaching hospital. Indian J Pharmacol 2013;45(2):117-20.
The Japan Glaucoma Society. Guidelines for Glaucoma. 2nd ed. Savona: Editrice Dogma; 2006.
Yanolff M, Duker JS, editors. Ophthalmology. London: Mosby
International Ltd.; 1999.
Khurana AK. Comprehensive Ophthalmology. 5th ed. India: New Age International; 2012.
Pan Y, Varma R. Natural history of glaucoma. Indian J Ophthalmol
;59 Suppl: S19-23.
Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 2006;90(3):262-7.
George R, Ve RS, Vijaya L. Glaucoma in India: Estimated burden of disease. J Glaucoma 2010;19(6):391-7.
Agarwal HC, Gulati V, Sihota R. Dr. Rajendra Prasad Centre for Ophthalmic Sciences. New Delhi, India: All India Institute of Medical Sciences.
Saepudin GB. Drug utilisation 90% (DU 90%) profile of antibiotic for treatment of hospitalised patients in Yogyakarta. J Llmaih Farmasi
;5:42-8.
Melrose D. Double deprivation public and private drug distribution from the perspective of the third world’s poor. World Dev 1983;11:181-6.
Sharma R, Khajuria R, Sharma P, Sadhotra P, Kapoor B, Kohli K,
et al. Glaucoma therapy: Prescribing pattern and cost analysis. JK Sci
;6:88-92.
Nies AS. Principles of therapeutics. In: Gilman AG, Rall TW, Nies AS, editors. The Pharmacological Basis of Therapeutics. 8th ed. New York: Pergamon Press; 1990. p. 62-83.
Pradhan SC, Shewade DG, Tekur U, Zutshi S, Pachiappan D, Dey AK, et al. Changing pattern of antimicrobial utilization in an Indian teaching hospital. Int J Clin Pharmacol Ther Toxicol 1990;28(8):339-43.
Atanasova I, Terziivanov D. Investigation on antibiotics in a hospital for a one-year period. Int J Clin Pharmacol Ther 1995;33(1):32-3.
Biswas NR, Jindal S, Siddiquei MM, Maini R. Patterns of prescription and drug use in ophthalmology in a tertiary hospital in Delhi. Br J Clin Pharmacol 2001;51(3):267-9.
Minocha KB, Bajaj S, Gupta K. A clinic pharmacological study of out- patient prescribing pattern of dermatological drugs in an Indian tertiary hospital. Indian J Pharmacol 2000;32:384-5.
Maini R, Verma KK, Biswas NR, Agrawal SS. Drug utilization study in dermatology in a tertiary hospital in Delhi. Indian J Physiol Pharmacol
;46(1):107-10.
Karunakaran R, Sadanandan SP. Computational insights on novel rock-1 inhibitors from marine compounds towards antiglaucoma therapeutics. Int J Pharm Clin Res 2016;8(9):1269-73.
Published
How to Cite
Issue
Section
The publication is licensed under CC By and is open access. Copyright is with author and allowed to retain publishing rights without restrictions.