ANALYSIS OF EFFICIENCY OF VACCINES AGAINST BRUCELLOSIS IN CATTLE IN THE REPUBLIC OF KAZAKHSTAN

Authors

  • Aspen Abutalip Department of , Kazakh Scientific-Research Veterinary Institute, Almaty, Kazakhstan
  • Nurali Matikhan Department of , Kazakh National Agrarian University, Almaty, Kazakhstan.
  • Serik Kanatbayev Department of , Kazakh Scientific-Research Veterinary Institute, Almaty, Kazakhstan
  • Marat Bazarbayev Department of , Kazakh Scientific-Research Veterinary Institute, Almaty, Kazakhstan
  • Viktor Vorobyov Department of , Veterinarian of Vostok-Moloko” Corporation of Eastern Kazakhstan, Almaty, Kazakhstan.

DOI:

https://doi.org/10.22159/ajpcr.2017.v10i6.16594

Keywords:

Brucellosis vaccine, Immunization, Efficiency, Anti-brucellosis measures

Abstract

Objective: This article analyzes the efficiency of live vaccines obtained from the strains of Brucella abortus 82 and 75/79-AV and RB-51 in some regions of Kazakhstan in 2012-2014 and recommends optimal scheme of their use.

Methods: There were analyzed the effectiveness of the use of live vaccines (manufactured in Russia) obtained from strains of B. abortus 19, 82 and 75/79-AV in combination with post-vaccination diagnostics of brucellosis in cattle in the farmsteads owned by Vostok-moloko Corporation in Eastern Kazakhstan in the period of 2012-2015.

Results: The results of these tests prove that studies of animals 1 month after the vaccination have helped to further identify the animals with hidden form of brucellosis provoked by R-vaccine, which explains the favorable outcome of the research.

Conclusion: The above-described scheme of anti-brucellosis activities ensures effective control of the epizootic process of brucellosis by establishing permanent†(continuous) immunity and permanent control of epizooty in brucellosis threatened/unsafe herds.

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References

Ivanov NP. Brucellosis in Animals and Measures of its Control. Almaty: Zoology; 2007. p. 617-25.

Abdrakhmanov S, Abutalip A, Baramova SA. Evaluation of Epizootic Process and Prediction of the Geographic Spread of Brucellosis in Farm Animals. Uralsk: Materials Medical Research and Production Center, West Kazakhstan Agrarian Technical University Named after Zhangirhan; 2012. p. 141-6.

Sultanov A, Ten V, Mikhalev N. Some of the changes in strategies for the elimination of brucellosis in animals. Actual Problems of Animal Diseases in Modern Conditions: The Materials of International Scientific and Practical Conference, Dushanbe; 2003. p. 72-5.

Mustafin M. Specific prevention of brucellosis in cattle. J Vet Sci 2004;13:50-62.

Sultanov A, Baramova S, Abutalip A, Ospanov Y. Epizootic Situation with Animal Brucellosis in the Republic of Kazakhstan. Vol. 11. Almaty: Collection of Scientific Materials by KazNIVI; 2015.

Schurig GG, Sriranganathan N, Corbel MJ. Brucellosis vaccines: Past, present and future. Vet Microbiol 2002;90(1-4):479-96.

Lord VR, Schurig GG, Cherwonogrodzky JW, Marcano MJ, Melendez GE. Field study of vaccination of cattle with Brucella abortus strains RB51 and 19 under high and low disease prevalence. Am J Vet Res 1998;59(8):1016-20.

Poester FP, Gonçalves VS, Paixão TA, Santos RL, Olsen SC, Schurig GG, et al. Efficacy of strain RB51 vaccine in heifers against experimental brucellosis. Vaccine 2006;24(25):5327-34.

Ashford DA, di Pietra J, Lingappa J, Woods C, Noll H, Neville B, et al. Adverse events in humans associated with accidental exposure to the livestock brucellosis vaccine RB51. Vaccine 2004;22(25-26):3435-9.

el Idrissi AH, Benkirane A, el Maadoudi M, Bouslikhane M, Berrada J, Zerouali A. Comparison of the efficacy of Brucella abortus strain RB51 and Brucella melitensis Rev 1 live vaccines against experimental infection with Brucella melitensis in pregnant ewes. Rev Sci Tech 2001;20(3):741-7.

Diptee MD, Adesiyun AA, Asgarali Z, Campbell M, Adone R. Serologic responses, biosafety and clearance of four dosages of Brucella abortus strain RB51 in 6-10 months old water buffalo (Bubalus bubalis). Vet Immunol Immunopathol 2006;109(1-2):43-55.

Mondal I, Sanyal S, Das S. Coagulation profile in patients suffering from acute brucellosis. Asian J Pharm Clin Res 2013;4:179-80.

Gupta A, Patel SS, Langute SM, Kolekar MR, Bhosale HP, Shinde SK, et al. Bacterial diseases of livestock animals and their impact on human health. Asian J Pharm Clin Res 2016;6:8-11.

Published

01-06-2017

How to Cite

Abutalip, A., N. Matikhan, S. Kanatbayev, M. Bazarbayev, and V. Vorobyov. “ANALYSIS OF EFFICIENCY OF VACCINES AGAINST BRUCELLOSIS IN CATTLE IN THE REPUBLIC OF KAZAKHSTAN”. Asian Journal of Pharmaceutical and Clinical Research, vol. 10, no. 6, June 2017, pp. 359-62, doi:10.22159/ajpcr.2017.v10i6.16594.

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