DAPSONE INDUCED DRESS: A CASE REPORT

Balaji O; Amita D; George MM; Meena Kumari K; Mohan Babu Vittalrao A

doi:10.22159/ajpcr.2017.v10i5.17554

Authors

Balaji O Post graduate , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.
Amita D Post graduate , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.
George MM Post graduate , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.
Meena Kumari K Associate professor, Kasturba Medical college , Manipal university , Manipal.
Mohan Babu Vittalrao A Associate Professor , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.

DOI:

https://doi.org/10.22159/ajpcr.2017.v10i5.17554

Keywords:

Dapsone, Adverse effect, Liver toxicity, Rashes, Eosinophilia

Abstract

Drug reaction with eosinophilia and systemic symptoms. is a very dangerous adverse drug effect causing rashes, eosinophilia, and multiple organ damage. Many drugs are implicated in causing DRESS with most common ones being antimicrobials and antiepileptics. Dapsone used in the treatment of Hansen's disease as a first-line agent is known for causing many side effects ranging from nausea, vomiting, insomnia, anaphylaxis, hypersensitivity reactions, rashes, muscle weakness, abdominal pain, and so on. Hence, we report a rare case of dapsone-induced DRESS in a tertiary care hospital in South India.

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