PHYTOCHEMICAL SCREENING OF ARTOCARPUS HIRSUTUS AND ITS ANTIMICROBIAL POTENTIAL

Shanmugapriya K; Akanya S; Anderson Clinton B; Berril Nanzy S; Prakash Pr; Suganya V

doi:10.22159/ajpcr.2017.v10i6.17669

Authors

Shanmugapriya K Department of , School of Biotechnology, Dr. G R Damodaran College of Science (Autonomous), Coimbatore, Tamil Nadu, India. http://orcid.org/0000-0002-9923-7432
Akanya S Department of , School of Biotechnology, Dr. G R Damodaran College of Science (Autonomous), Coimbatore, Tamil Nadu, India.
Anderson Clinton B Department of , School of Biotechnology, Dr. G R Damodaran College of Science (Autonomous), Coimbatore, Tamil Nadu, India.
Berril Nanzy S Department of , School of Biotechnology, Dr. G R Damodaran College of Science (Autonomous), Coimbatore, Tamil Nadu, India.
Prakash Pr Department of , School of Biotechnology, Dr. G R Damodaran College of Science (Autonomous), Coimbatore, Tamil Nadu, India.
Suganya V Department of , School of Biotechnology, Dr. G R Damodaran College of Science (Autonomous), Coimbatore, Tamil Nadu, India.

DOI:

https://doi.org/10.22159/ajpcr.2017.v10i6.17669

Keywords:

Artocarpus hirsutus, Antimicrobial, Alkaloids, Bacteria, Phytoconstituents

Abstract

Objective: In the present study, the effort was aimed to evaluate the phytochemical components, antioxidant activity, and antimicrobial activity of Artocarpus hirsutus fruit and leaf.

Methods: Each plant materials were extracted with two suitable solvents such as acetone and ethanol. Then, the extracts were tested for the presence of active phytoconstituents and antimicrobial activity. Then, it was subjected to antimicrobial activity against fungal and bacterial strains.

Results: The present study suggested that the selected plant extracts of A. hirsutus exhibit major phytoconstituents, such as alkaloids, glycosides, terpenoids, phenols, and saponins. Furthermore, the results showed that acetone fruit extract of A. hirsutus and ethanolic fruit extract of A. hirsutus exhibited significant antimicrobial activity with a maximum zone of inhibition against Staphylococcus aureus and Aspergillus tamarii.

Conclusion: The present study also exhibited remarkable antimicrobial activity against all the test microorganisms due to the presence of major bioactive phytochemicals

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Author Biography

Shanmugapriya K, Department of , School of Biotechnology, Dr. G R Damodaran College of Science (Autonomous), Coimbatore, Tamil Nadu, India.

Biotechnology

References

Pendyala V, Ramesh BJ, Vidyadhara S. Phytochemical and pharmacological evaluation of Commiphora mukul for antidepressant activity in albino mice. Asian J Pharm Clin Res 2017;10(1):360-3.

Shanmugapriya K, Saravana PS, Harsha P, Peer M, Binnie W. A comparative study of antimicrobial potential and phytochemical analysis of Artocarpus heterophyllus and Manilkara zapota seed extracts. J Pharm Res 2011;4(8):2587-9.

Olayinka AA, Okoh AI. Preliminary phytochemical screening and in vitro antioxidant activities of the aqueous extract of Helichrysum longifolium. BMC Complement Altern Med 2010;10(21):1-8.

Shanaida LM, Ivanusa I, Kernychna I. Phytochemical analysis of secondary metabolites of Satureja hortensis. Int J Pharm Pharm Sci 2017;9(2):315-8.

Kumari S. Evaluation of phytochemical analysis and antioxidant and antifungal activity of Pithecellobium dulce Leaves extract. Asian J Pharm Clin Res 2017;10(1):370-5.

Buvaneswari K, Ramamoorthy D, Velanganni J. Preliminary phytochemical and antimicrobial activity studies on the leaves of the Indian plant Thevetia neriifolia Juss. World J Agric Sci 2011;7(6):659-66.

Raghu V, George S, Krishna RV, Sindhu KK. Bioactive properties of phenolics present in Oroxylu mindicum - A review. J Pharmacol Phytochem 2013;2(3):23-7.

Patil RB, Kore BA. Phytoconstituents, pigments, gas chromatography mass spectrometry analysis, and allelopathy effect of Alternanthera ficoidea (L.) P. Beauv. Asian J Pharm Clin Res 2017;10(2):103-8.

Cicera NF, Heloisa HF, Maria CM, Celestina ES, Glaucia MM, Fernando GF, et al. Evaluation of the modulatory and antibacterial activity of the ethanolic extract and fractions of Duguetia furfuracea A. St. Hil. Afr J Pharm Pharmacol 2014;8(1):16-20.

Shanmugapriya K, Thayumanavan T. Phytochemical screening and antimicrobial potential on ethanolic extract of Gnaphalium polycaulon Pers., ethnomedicinal plant used by Nilgiri tribe from Western Ghats, Tamil Nadu, India. Med Plants Int J Phytomed Relat Ind 2016;8(2):168-71.

Akhil H, Revikumar KG, Divya D. Artocarpus: A review of its phytochemistry and pharmacology. J Pharm Search 2014;9(1):7-11.

Anu V, Rajkumar SM, Mujeeb CA, Vinod MK. Biosynthesis of silver nanoparticles from Artocarpus hirsutus leaf extracts its antimicrobial activity and phytochemical analysis. Int J Res Pharm Nano Sci 2015;4(1):28-39.13. Tang YP, Linda BL, Franz LW. Proximate analysis of Artocarpus odoratissimus (Tarap) in Brunei Darussalam. Int Food Res J 2013;20(1):409-15.

Madhavi Y, Bhaskar RD, Raghava RT. Studies on phytochemical analysis and antimicrobial activity of Artocarpus communis fruit latex against selected pathogenic microorganisms. Indo Am J Pharm Res 2013;3(1):1360-70.

Vinay SM, Venkatachalapathy R, Makari HK, Ramesh BS. Phytochemical analysis and antimicrobial activity of Artocarpus hirsutus: An in vitro study. Int J Pharm Bio Sci 2014;5(3):98-104.

Harborne JB. Phytochemical Methods. London: Chapman and Hall Ltd.; 1973. p. 49-188.

Lekshmi NC, Sumi SB, Viveka S, Brindha JR. Antibacterial activity of nanoparticles from Allium sp. J Microbiol Biotechnol Res 2012;2:115-9.

Lakhdar L, Farah A, Lahlou I, Rida S, Bouziane A, Ennibi O. Antibacterial effectiveness of selected moroccan essential oils against the highly virulent Jp2 clone of Aggregatibacter actinomycetemcomitans. Int J Pharm Pharm Sci 2017;9(2):47-51.

Tran MH, Pham VT, Do ND, Nguyen TT, Ba TC, Le TT, et al. Antimicrobial, antioxidant activities and cytotoxicity evaluation of Artocarpus nigrifolius C.Y. Wu from Vietnam. Afr J Microbiol Res 2013;7(15):1326-31.

Okuda T. Systematics and health effects of chemically distinct tannins in medicinal plants. Phytochemistry 2005;66(17):2012-31.

Scalbert A. Antimicrobial properties of tannins. Phytochemistry 1991;30(12):3875-83.

Jigna P, Sumitra C. Antibacterial and phytochemical studies on twelve species of Indian medicinal plants. Afr J Biomed Res 2007;10:175-81.

Amin MM, Sawhney SS, Jassan MM. Quantitative and qualitative analysis of phytochemicals of Taraxacum officinale. Wudpecker J Pharm Pharmacol 2013;2(1):1-5.

Ranganathan R, Vijayalakshmi R, Parameswari P. Ethnomedicinal survey of Jawadhu hills in Tamil Nadu. Asian J Pharm Clin Res 2012;5(2):45-9.

Vikrant A, Narender T, Kashyap CP. Preliminary phytochemical analysis of the extracts of Psidium leaves. J Pharmacogn Phytochem 2012;1(1):1-5.

Odunbaku OA, Ilusanya OA, Akasoro KS. Antibacterial activity of ethanolic leaf extract of Ficus exasperata on Escherichia coli and Staphylococcus albus. Sci Res Essay 2008;3(11):562-4.

KonÃ© WM, Atindehou KK, Terreaux C, Hostettmann K, TraorÃ© D, Dosso M. Traditional medicine in north CÃ´te-dâ€™Ivoire: Screening of 50 medicinal plants for antibacterial activity. J Ethnopharmacol 2004;93(1):43-9.