VALPROIC ACID TOXICITY INDUCED BY LACOSAMIDE: A RARE CASE REPORT

Karthika Ashok Kumar; Chanshi Chandran; Remya Reghu

doi:10.22159/ajpcr.2017.v10i9.18820

Authors

Karthika Ashok Kumar Department of Pharmacy Practice, Amrita School of Pharmacy, Amrita University, Kochi - 682 041, Kerala, India.
Chanshi Chandran Department of Pharmacy Practice, Amrita School of Pharmacy, Amrita University, Kochi - 682 041, Kerala, India.
Remya Reghu Department of Pharmacy Practice, Amrita School of Pharmacy, Amrita University, Kochi - 682 041, Kerala, India.

DOI:

https://doi.org/10.22159/ajpcr.2017.v10i9.18820

Keywords:

Valproic acid, hyperammonemic encephalopathy, lacosamide

Abstract

Valproic acid is commonly used in the treatment of both focal and generalized epilepsies and is often tolerated well.Valproic acid is usually tolerated well, but serious complications, including hepatotoxicity and hyperammonemic encephalopathy, may occur. Here we report a case of valproic acid induced hyperammonemic encephalopathy on concomitant use with lacosamide.

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Author Biography

Karthika Ashok Kumar, Department of Pharmacy Practice, Amrita School of Pharmacy, Amrita University, Kochi - 682 041, Kerala, India.

Lecturer, Dept of Pharmacy Practice

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