LAMOTRIGINE INDUCED DRESS SYNDROME

Authors

  • SAURABH AGARWAL Post graduate , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.
  • Balaji O Post graduate , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.
  • Amita Priya d Post graduate , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.
  • Mohan A Associate professor , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.
  • Meena K ASSOCIATE PROFESSOR , Department of Internal medicine, Kasturba Medical college , Manipal university , Manipal.

DOI:

https://doi.org/10.22159/ajpcr.2017.v10i9.18876

Keywords:

LIVER TOXICITY, SKIN RASH, EIOSINOPHILIA, ADVERSE DRUG REACTION

Abstract

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, is a type of hypersensitivity reaction, mainly due to anti-epileptic drugs. Lamotrigine is a newer broad spectrum antiepileptic that can be used in both children and adults. Lamotrigine induced DRESS syndrome is a rare case with incidence of 1/1000 to 1/10000. This syndrome manifests as rash, fever, tender lymphadenopathies, hepatitis, and eosinophilia. This case highlights the need for early diagnosis and treatment of such a rare and life threatening event because early detection of the condition leads to early recovery of the patient. Further re-exposure to the drug should be avoided.

 

 

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References

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Published

01-09-2017

How to Cite

AGARWAL, S. ., B. O, A. Priya d, M. A, and Meena K. “LAMOTRIGINE INDUCED DRESS SYNDROME”. Asian Journal of Pharmaceutical and Clinical Research, vol. 10, no. 9, Sept. 2017, pp. 3-4, doi:10.22159/ajpcr.2017.v10i9.18876.

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Case Study(s)

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