SWEET FUTURE OF STEVIA: A MAGICAL SWEETENER

Jeevan Jyoti; Maninderjeet Kaur; Vijay Mishra; Amit Mittal

doi:10.22159/ajpcr.2018.v11i2.20295

Authors

Jeevan Jyoti Department of Quality Assurances, Lovely Institute of Technology (Pharmacy), Lovely Professional University, Phagwara (Punjab), India-144411
Maninderjeet Kaur Department of Pharmaceutics, Lovely Institute of Technology (Pharmacy), Lovely Professional University, Phagwara, Punjab, India.
Vijay Mishra Department of Pharmaceutics, Lovely Institute of Technology (Pharmacy), Lovely Professional University, Phagwara, Punjab, India.
Amit Mittal Department of Pharmaceutical Chemistry, Lovely Institute of Technology (Pharmacy), Lovely Professional University, Phagwara, Punjab, India.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i2.20295

Keywords:

The plant Stevia rebaudiana is mainly found in tropical and subtropical regions from western North America to South America This genus is having near about 240 species of shrubs and herbs in the sunflower family (Asteraceae) It exhibits various proper

Abstract

Â The plant Stevia rebaudiana is mainly found in tropical and subtropical regions from western North America to South America. This genus is having near about 240 species of shrubs and herbs in the sunflower family (Asteraceae). It exhibits various properties such as antibacterial, antifungal, anti-inflammatory, antimicrobial, antiviral, antiyeast, cardiotonic, diuretic, hypoglycemic, hypotensive tonic, and vasodilator effect. It is an important source of a number of antioxidants, for example, benzoic acid, caffeic acid, chlorogenic acid, ferulic acid, rozmaric acid, protocatechuic acid, salicylic acid, and their derivatives and flavonoids including campherol derivatives, catechin, and its derivatives, epicatechin, luteolin, and its derivatives, rutin, and its derivatives. Day by day, there is remarkable increase in demand of high potency sweeteners. The increasing number of diabetic patients and health conscious individuals would push forward the need for alternatives to sugar. The extract from leaves of Stevia is 200 times sweeter than sugar (glucose, fructose, sucrose, maltose, and lactose). Stevia is a potential alternative source for replacing artificial sweeteners such as saccharin, aspartame, and asulfam.

Downloads

Download data is not yet available.

Author Biographies

Jeevan Jyoti, Department of Quality Assurances, Lovely Institute of Technology (Pharmacy), Lovely Professional University, Phagwara (Punjab), India-144411

M.Pharmacy student

Department of Quality Assurances, Lovely Institute of Technology (Pharmacy), Lovely Professional University, Phagwara (Punjab), India-144411

Maninderjeet Kaur, Department of Pharmaceutics, Lovely Institute of Technology (Pharmacy), Lovely Professional University, Phagwara, Punjab, India.

M.Pharmacy student

Department of Pharmaceutics, Lovely Institute of Technology (Pharmacy), Lovely Professional University, Phagwara (Punjab), India-144411

Vijay Mishra, Department of Pharmaceutics, Lovely Institute of Technology (Pharmacy), Lovely Professional University, Phagwara, Punjab, India.

Associate Professor,

Department of Pharmaceutics, Lovely Institute of Technology (Pharmacy), Lovely Professional University, Phagwara (Punjab), India-144411

Amit Mittal, Department of Pharmaceutical Chemistry, Lovely Institute of Technology (Pharmacy), Lovely Professional University, Phagwara, Punjab, India.

Associate Professor, Department of Pharmaceutical Chemistry, Lovely Institute of Technology (Pharmacy), Lovely Professional University, Phagwara (Punjab), India-144411

References

Ramesh K, Singh V, Megeji NW. Cultivation of stevia (Stevia rebaudiana Bertoni): A comprehensive review. Adv Agron 2006;89:137-77.

Kinghorn AD, editor. Overview. Stevia, the Genus of Stevia, Medicinal and Aromatic Plants Industrial Profiles. London: Taylor and Francis; 2002. p. 1-17.

Gupta R, Yadav V, Rastogi M. A review on importance of natural sweetener, a zero calorie plant-stevia-having medicinal and commercial importance. Int J Food Nutr Sci 2014;3:90-4.

Available from: http://www.internationalsteviacouncil.org. [Last accessed on 2017 Apr 19].

Tavarini S, Angelini LG. Stevia rebaudiana bertoni as a source of bioactive compounds: The effect of harvest time, experimental site and crop age on steviol glycoside content and antioxidant properties. J Sci Food Agric 2013;93:2121-9.

WÃ¶lwer-Rieck U. The leaves of Stevia rebaudiana (Bertoni), their constituents and the analyses thereof: A review. J Agric Food Chem 2012;60:886-95.

Brandle JE, Starratt AN, Gijzen M. Stevia rebaudiana: Its agricultural, biological, and chemical properties. Can J Plant Sci 1998;78:527-36.

Ohta M, Sasa S, Inoue A, Tamai T, Fujita I, Morita K, et al. Characterization of novel steviol glycosides from leaves of Stevia rebaudiana morita. J Appl Glycosci 2010;57:199-209.

Charturvedula VS, Clos JF, Rhea J, Milanowski D, Mocek U, DuBois GE, et al. Minor diterpenoid glycosides from the leaves of Stevia rebaudiana. Phytochem Lett 2011;6:175-8.

Chaturvedula VS, Rhea J, Milanowski D, Mocek U, Prakash I. Two minor diterpene glycosides from the leaves of Stevia rebaudiana. Nat Prod Commun 2011;6:175-8.

Chaturvedula VS, Prakash I. Structures of the novel diterpene glycosides from Stevia rebaudiana. Carbohydr Res 2011;346:1057-60.

Charturvedula VS, Upreti M, Prakash I. Structures of the novel a-glycosyl linked diterpene glycoside from Stevia rebaudiana. Carbohydr Res 2011;346:2034-8.

Kumari M, Chandra S. Phytochemical studies and estimation of major steviol glycosides in varied parts of Stevia rebaudiana. Int J Pharm Pharm Sci 2015;7:62-5.

Charturvedula VS, Upreti M, Prakash I. Diterpene glycosides from Stevia rebaudiana. Molecules 2011;16:3552-62.

Zimmermann BF. Tandem mass spectrometric fragmentation patterns of known and new steviol glycosides with structure proposals. Rapid Commun Mass Spectrom 2011;25:1575-82.

Kim SH, Dubois GF. Natural high potency sweeteners. In: Marie S, Piggott JR, editors. Handbook of Sweeteners. Glasgow, New York: Blacki Avi; 1991.

Prakash I, Dubois GE, Clos JF, Wilkens KL, Fosdick LE. Development of rebiana, a natural, non-caloric sweetener. Food Chem Toxicol 2008;46 Suppl 7:S75-82.

McGarvey BD, Attygalle AB, Starratt AN, Xiang B, Schroeder FC, Brandle JE, et al. New non-glycosidic diterpenes from the leaves of Stevia rebaudiana. J Nat Prod 2003;66:1395-8.

Supriyadi S, Siswandono S, Yuwono M. Method development and validation for the simultaneous determination Of stevioside, rebaudioside-A, rebaudioside C and dulcoside a contained in Stevia rebaudiana Bertoni using HPLC-ELSD. Int J Pharm Pharm Sci 2016;8:1-5.

Oshima Y, Saito J, Hikino H. Sterebin-E, sterebin-F, sterebin-G and sterebin-H, diterpenoids of Stevia rebaudiana leaves. Phytochemistry 1988;27:624-6.

Ibrahim NA, El-Gengaihi S, Motawe H, Riad SA. Phytochemical and biological investigation of Stevia rebaudiana Bertoni; 1-labdane-type diterpene. Eur Food Res Technol 2007;224:483-8.

Sholichin M, Yamasaki K, Miyama R, Yahara SS, Tanaka O. Labdane-type diterpenes from Stevia rebaudiana. Phytochemistry 1980;19:326.

Kim IS, Yang M, Lee OH, Kang SN. The antioxidant activity and the bioactive compound content of Stevia rebaudiana water extracts. LWT Food Sci Technol 2011;44:1328-32.

KarakÃ¶se H, Jaiswal R, Kuhnert N. Characterization and quantification of hydroxycinnamate derivatives in Stevia rebaudiana leaves by LC-MSn. J Agric Food Chem 2011;59:10143-50.

Cacciola F, Delmonte P, Jaworska K, Dugo P, Mondello L, Rader JI, et al. Employing ultra-high pressure liquid chromatography as the second dimension in a comprehensive two-dimensional system for analysis of Stevia rebaudiana extracts. J Chromatogr A 2011;1218:2012-8.

Ghanta S, Banerjee A, Poddar A, Chattopadhyay S. Oxidative DNA damage preventive activity and antioxidant potential of Stevia rebaudiana (Bertoni) bertoni, a natural sweetener. J Agric Food Chem 2007;55:10962-7.

Tadhani MB, Patel VH, Subhash R. In vitro antioxidant activities of Stevia rebaudiana leaves and callus. J Food Compos Anal 2007;20:323-9.

Li J, Jiang H, Shi R. A new acylated quercetin glycoside from the leaves of Stevia rebaudiana bertoni. Nat Prod Res 2009;23:1378-83.

Michalik A, Hollinshead J, Jones L, Fleet GW, Yu CY, Hu XG, et al. Steviamine, a new indolizidine alkaloid from Stevia rebaudiana. Phytochem Lett 2010;3:136-8.

Winchester BG. Iminosugars: From botanical curiosities to licensed drugs. Tetrahedron 2009;20:645-51.

EFSA. Scientific opinion on the safety and efficacy of thaumatin for all animal species. EFSA J 2011;9:2354-64.

Grembecka M. Sugar alcohols their role in the modern world of sweeteners a review. Eur Food Res Technol 2015;241:1-14.

Livesey G. Health potential of polyols as sugar replacers, with emphasis on low-glycaemic properties. Nutr Res Rev 2003;16:163-91.

Nurkhasanah, Minangsari DN, Yulianny VA. The combination of rosella (Hibiscus sabdariffa, L) and stevia (Stevia rebaudiana) extracts increase the antioxidant activity and stability. Int J Pharm Pharm Sci 2016;8:411-2

Taylor L. The Healing Power of Natural Herbs. Garden City Park, New York: Square One Publishers, Inc.; 2005.