SOCIO-EPIDEMIOLOGICAL EVALUATION OF TUBERCULOSIS AND IMPACT OF PHARMACEUTICAL CARE ON MEDICATION ADHERENCE AMONG TUBERCULOSIS PATIENTS
DOI:
https://doi.org/10.22159/ajpcr.2018.v11i2.20503Keywords:
Knowledge, Medication adherence, TuberculosisAbstract
 Objectives: Tobjective of this study is to assess the knowledge and to monitor medication adherence among tuberculosis (TB) patients.
Methods: During the 6 months prospective interventional study, a data collection form was designed. The knowledge and adherence levels were assessed using quantified questionnaires. Patients were counseled using patient information leaflets and reassessed during follow-up.
Results: Results were analyzed using one-way ANOVA and Pearson's correlation.
Key findings: Among the 65 patients who completed 3 reviews during 6-month follow-up study, there was a statistically significant improvement in medication adherence score from baseline in correspondence with the increase in knowledge baseline to first follow-up revealed a mean increase in medication adherence level of 2.723±1.625 (p<0.05) in correspondence with a mean increase in knowledge level 24.8±5.04 (p<0.05) which is statistically significant. First follow-up to second follow-up showed a mean increase in medication adherence of 1.400±1.072 (p<0.05) in correspondence with a mean increase in knowledge level 28.32±4.4 (p<0.05) which is statistically significant. Second to third follow-up showed a mean increase in medication adherence of 0.123±0.450 (p<0.05) in correspondence with a mean increase in knowledge level 34.18±2.74 (p<0.05) which is statistically significant.
Conclusion: The efforts to improve awareness on TB patients such as providing patient counseling and education could enhance adherence to therapies and thus could improve outcomes and quality of life.
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Olakunale OS, Olanrewaju O, Olalekan AW, Bello AO, Akinleye C, Oluwatoyin OA. Knowledge of tuberculosis management using directly observed treatment short course therapy among final year medical students in south western Nigeria. Afr Med J 2014;5:1-5.
Choi H, Chung H, Muntaner C, Lee M, Kim Y, Barry CE, et al. The impact of social conditions on patient adherence to pulmonary tuberculosis treatment. Int J Tuberc Lung Dis 2016;20:948-54.
Rehman F, Rao S, Hasan A, Parmehwar H, Parameshwar H, Raoof MA, et al. An assessment of patient’s perception on tuberculosis, prevention and control in a teaching hospital. Adv Pharmacoepidemiol Drug Saf 2016;5:201.
Sukumaran P, Venugopal KP, Manjooran RS. A study of compliance with DOTS. Indian J Tuberc 2002;49:205-8.
Pandit N, Choudhary SK. A study of treatment compliance in directly observed therapy for tuberculosis. Indian J Community Med 2006;31:241-3.
Gupta RK, Gupta A, Jamwal DS, Suri SP. A socio-epidemiological study of tuberculosis in a rural area. JK Science 2002;4:20-2.
Tuberculosis in a rural population of South India: A five-year epidemiological study. Bull World Health Organ 1974;51:473-88.
Sumartojo E. When tuberculosis treatment fails: A social behaviour account of patient adherence. Am Rev Respir Dis 1993;147:1311-8.
Gad A. Compliance with anti-tuberculosis drugs among tuberculosis patients in Alexandria, Egypt. PLosMed 1997;3:244-50.
Solliman MA, Hassali MA, Haddad MA, Hadida MM, Saleem F, Atif M, et al. Assessment of knowledge towards tuberculosis among the general population in North East Libya. J Appl Pharm Sci 2012;2:24-30.
Stewart MA. What is successful doctor patient interview? A study interactions and outcomes. Soc Sci Med 1984;19:167-75.
Tekle B, Mariam DH, Ali A. Defaulting from DOTS and its determinants in three districts of Arsi zone in Ethiopia. Int J Tuberc Lung Dis 2002;6:573-9.
Boyle SJ, Power JJ, Ibrahim MY, Watson JP. Factors affecting patient compliance with ant tuberculosis chemotherapy using the directly observed treatment, short course strategy (DOTS). Int J Tuberc Lung Dis 2002;6:307-12.
Thomas C. A literature review of the problems of delayed presentation for treatment and non-completion of treatment for tuberculosis in less developed countries and ways of addressing these problems using particular implementations of the DOTS strategy. J Manag Med 2002;16:371-400.
Drucker E, Elcabes P, Bosworth W. Childhood tuberculosis in Bronx (New York). Lancet 1994;343:1482.
Bhardwaj A, Kumar R, Dabas V, Alam N. Assessment and enhancing adherence to treatment regimen in tuberculosis outpatients. Int J Pharm Pharma Sci 2012;4:517-22.
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