DOSAGE FORM DEVELOPMENT AND PRELIMINARY PHYSICOCHEMICAL CHARACTERIZATION OF TRIKANTAKADI KVATHA

Authors

  • Swati Sharma Department of Ayurvedic Pharmacy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India.
  • Dileep Singh Baghel Department of Ayurvedic Pharmacy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India.
  • Saurabh Singh Department of Ayurvedic Pharmacy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India.
  • Sachin Kumar Singh

DOI:

https://doi.org/10.22159/ajpcr.2017.v10s4.21336

Keywords:

Trikantakadi kvatha, Ghana vati, Syrup, Tincture

Abstract

 

 Objective: This is aimed to study the development of different dosage form and physicochemical characterization of Trikantakadi Kvatha (TK).

Methods: Stability, shelf life, non-convenient, and large dosages administration are the major concern for Kvatha. To overcome these problems, an effort has been made to modify the formulation without changing its efficacy into various dosage forms such as tablet, syrup, and tincture. Comparative pharmacognostic, physicochemical, and phytochemical parameters of crude herbs and prepared formulations were investigated. TK was prepared by classical method mentioned in literature and converted into TK syrup, TK Ghana vati, and Trikantakadi tincture (TT). Precaution should be taken during the processing of formulations. TT placed at a dark place in airtight container.

Results: Physicochemical and phytochemical investigations are not shown any remarkable variations with various prepared dosage forms. The Rf range observed between the 0.08 and 0.80 follows the standard value when compared with the reference of plant drug used for the preparation of dosage form.

Conclusion: The prepared dosages forms were not exhibited any remarkable difference according to thin-layer chromatography studies and physicochemical parameters. However, the developed dosage forms are more stable than kvatha.

Downloads

Download data is not yet available.

Author Biography

Swati Sharma, Department of Ayurvedic Pharmacy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India.

School of Pharmaceutical Sciences, Asst. Prof

References

Tripathi B, editor. Sharanagadhara Samhita with Dipika Hindi Commentaryâ€. Madhyam Khand. Ch. 9. Varanasi: Chaukhamba Subharti Prakashan; 2008.

Shastri S. Agnivesha Charaka Samhita, Sutra Sthana 4/6. Varanasi: Chaukhamba Bharti Academy; 2006. p. 71.

Sushruta. Sushruta Samhita, Chikitsa Sthana 31/8. Varanasi: Chaukhambha Sanskrit Sansthan; 2005.

Tripathi RD. Astanga Samgraha, Sutra Sthana 178/103. Varanasi: Chaukhamba Sanskrit Pratisthan; 2003.

Pandit Sarangadhara. Sarangadhara Samhita, Madhyam Khand 2/3. Varanasi: Chaukhamba Surbharti Prakshana; 2010. p. 133-4.

Jha CB. Yogatarangini 18/20. Varanasi: Chaukhamba Vidyabhavan; 2003. p. 76.

Narayan SR. Ayurveda Sar Samghara, Reprint. 11th ed. New Delhi: Vaidyanatha Ayurved Bhavan; 2011. p. 707.

Krishna G. Rasatantrasaar Va Sidhapryoga Samghra, Ist Part. Ajmair: Krishna Gopal Ayurved Bhavan; 2005. p. 704.

Gupta AK, Tandan N, Sharma M: Quality Standard of Indian Medicinal Plants. Vol. I, II, IV, VII, VIII. New Delhi: Indian Council of Medicinal Research; 2003, 2005, 2006, 2008, 2010.

Bharat DK, Patgiri BJ, Prajapati PK. Standard manufacturing procedure for syrup and tablet forms of Jwarahara Dashemani. Int Q J Res Ayurveda 2010;31(2):255-9.

Lean L, Liebermon HA, Kaning JL. The Theory and Practice of Industrial Pharmacy. 3rd ed. Bombay: Varghese Publishing House; 1987.

Anonymous. Protocol for Testing Ayurveda, Siddha and Unani medicines. Ghaziabad: Government of India, Ministry of Health and Family Welfare, Department of AYUSH, PLIM; 2006.

Anonymous. The Ayurvedic Pharmacopoeia of India Part-I. Appendix-2,3,5. 1st ed., Vol. VI. New Delhi: Government of India, Ministry of Health and Family Welfare Department of Ayush; 2008.

Khar RK, Vyas SP, Ahmad FJ, Jain GK, Lachman L, Lieberman HA. The Theory and Practice of Industrial Pharmacy. 4th ed. Philippines: CBS Publishers & Distributors Pvt Ltd.; 2014.

Kokate CK. Practical Pharmacognosy. New Delhi: Vallabha Prakashan; 1994.

Kumar SP, Prasan ND. Development and evaluation of polyherbal syrup from some herbs used as expectorant. World J Pharm Pharm Sci 2013;2(5):3848-53.

Published

01-09-2017

How to Cite

Sharma, S., D. S. Baghel, S. Singh, and S. K. Singh. “DOSAGE FORM DEVELOPMENT AND PRELIMINARY PHYSICOCHEMICAL CHARACTERIZATION OF TRIKANTAKADI KVATHA”. Asian Journal of Pharmaceutical and Clinical Research, vol. 10, no. 16, Sept. 2017, pp. 52-56, doi:10.22159/ajpcr.2017.v10s4.21336.

Issue

Section

Original Article(s)

Most read articles by the same author(s)

<< < 1 2