ISOLATION OF SOME POTENTIAL PHYTOCOMPOUNDS FROM ADHATODA VASICA THROUGH GAS CHROMATOGRAPHY-MASS SPECTROSCOPY ANALYSIS

Authors

  • Aziz Mohammad Khan Department of Microbiology, JECRC University, Jaipur, Rajasthan, India
  • Seema Bhadauria Department of Microbiology, JECRC University, Jaipur, Rajasthan, India

DOI:

https://doi.org/10.22159/ajpcr.2017.v10i12.21630

Keywords:

Adhatoda vasica, Medicinal plant, Screen, Phytocompounds, Gas chromatography-mass spectroscopy

Abstract

 

 Objective: The aim of this study is to screen the medicinal compounds present in the leaves, shoots, and flowers of Adhatoda vasica by gas chromatography-mass spectroscopy (GC-MS) analysis.

Methods: Plant leaves, shoots, and flowers were collected, washed, shade dried, and powdered. Methanol extracts of all plant parts were prepared by soxhlation method. All the plant part extracts were analyzed for the identification of phytocompounds present in plant parts using GC-MS and matched by the National Institute of Standards and Technology library.

Results: A wide range of fatty acids and the heterocyclic compound was identified which is responsible for antibacterial, antifungal, anti-inflammatory, and antimycotic activity.

Conclusion: The study concludes that A. vasica have many important important biologically compounds so it can be recommended as a plant of pharmaceutical importance.

Downloads

Download data is not yet available.

References

Salna KP, Sreejith K, Uthiralingam M, Prince MA, Milton MC, Fleming AT. A comparative study of phytochemicals investigation of Andrographis paniculata and Murraya koenigii. Int J Pharm Pharm Sci 2011;3(3):291-2.

Arunkumar K, Chandrashekar KR. Phytochemical evaluation and in vitro antimicrobial and antioxidant studies of leaf and stem bark extracts of Polyalthia fragrans (Dalz.) bedd.-an endemic species of Western Ghats. Int J Pharm Pharm Sci 2017;9(8):20-4.

Shinwari ZK, Shah M. The ethnobotany of Haran district, Balochistan, Pakistan. Proc Sym Med 1995;12:35-8.

Chopra RN. Indigenous Drugs of India. Calcutta: Academic Publishers; 1982. p. 264-6.

Rastogi RP, Mehrotra BN. Compondium of Indian Medicinal Plants. Vol. 1-5. New Delhi, India: Central Drug Research Institute, Lucknow and National Institute of Science Communication; 1994. p. 188-9.

Friesner RA, Murphy RB, Repasky MP, Frye LL, Greenwood JR, Halgren TA, et al. Extra precision glide: docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes. J Med Chem 2006;49(31):6177-96. 7. Elgal SN, Jasmine R. Identification of the compounds of Adhatoda vasica by gas chromatography-mass spectrometry analysis and probing: The mode of action of the compounds by in silico study. Asian J Pharm Clin Res 2017;10(4):105-8.

Adnan M, Hussain J, Shah MT, Ullah F, Shinwari JK, Bahadar A, et al. Proximate and nutrient composition of medicinal plants of humid and Sub-humid regions in Northwest Pakistan. J Med Plant Res 2010;4:339-45.

Lal SD, Yadav BK. Folk medicine of Kurukshetra district (Haryana), India. Econ Bot 1983;37:299-305.

Subramanian SS, Nagarajan S. Flavonoids of the seeds of Crotalaria retusa and Crotalaria striata. Curr Sci 1969;38:65.

Bhadauria S, Kumar P. In vitro antimycotic activity of some medicinal plants against human pathogenic dermatophytes. Indian J Fundam Appl Life Sci 2011;1(2):1-10.

Kumaravel S, Kumar PP, Vasuki P. GC-MS study on microbial degradation of lindane. Int J Appl Biochem 2010;6(3):363-6.

Russell AD. Mechanisms of bacterial resistance to non-antibiotics: food additives and food and pharmaceutical preservatives. J Appl Bacteriol 1991;71(3):191-201.

McGaw LJ, Jäger AK, van Staden J. Isolation of antibacterial fatty acids from Schotia brachypetala. Fitoterapia 2002;73(5):431-3.

Seidel V, Taylor PW. In vitro activity of extracts and constituents of Pelagonium against rapidly growing mycobacteria. Int J Antimicrob Agents 2004;23(6):613-9.

Duke JA, Beckstrom-Sternberg SM. Phytochemical and Ethnobotanical Databases, Duke’s Phytochemical and Ethnobotanical Databases. Available from: http://huilesutiles.eu/docs/patchouli.pdf. [Last cited on 2013 Mar 11].

Published

01-12-2017

How to Cite

Khan, A. M., and S. Bhadauria. “ISOLATION OF SOME POTENTIAL PHYTOCOMPOUNDS FROM ADHATODA VASICA THROUGH GAS CHROMATOGRAPHY-MASS SPECTROSCOPY ANALYSIS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 10, no. 12, Dec. 2017, pp. 328-32, doi:10.22159/ajpcr.2017.v10i12.21630.

Issue

Section

Original Article(s)