MEDICINALLY IMPORTANT PLANT CLEOME GYNANDRA: A PHYTOCHEMICAL AND PHARMACOLOGICAL EXPLANATION
DOI:
https://doi.org/10.22159/ajpcr.2018.v11i1.22037Keywords:
Cleomaceae, Cleome gynandra Linn, Pharmacological, Phytochemicals, Pink mutant varietyAbstract
Â
 Cleome genus includes 601 plant species from the family Cleomaceae. Of more than 600 plants, 206 (34.3%) plants are having accepted species names. Cleome gynandra Linn. is a well-known medicinal plant with traditional and pharmacological importance. A good number of secondary plant metabolites have also been isolated from different parts of C. gynandra. Our investigation confirms two mutant varieties of C. gynandra exists in India. Accordingly, the objective of this study was designed to critically evaluate the pharmacological and phytochemical evaluation of C. gynandra of two mutant variety, to provide a consolidated platform for research potential of both the mutant varieties of C. gynandra. Careful scrutiny reveals that the plant possesses a huge range pharmacological applications, such as anti-inflammatory, free radical scavenging, anticancerous, immunomodulator, and antidiabetic agents. To arrive its pharmacological importance the published papers also shown an enormous amount of phytochemicals endorsement. Scientific perusal reveals different parts of the plant has an immense medicinal importance which proofs its traditional use round the glove. But in North-Eastern region of India, the same plant abundantly found in pink mutant variety. To date, there is not much research investigation for this mutant variety to validate its pharmacological importance. Therefore, research needs to scrutinize and compare the medicinal claims of the pink mutant variety in the bio-diverse region of North-East India.
Downloads
References
Sharma M, Sharma CL. Indigenous uses of medicinal plants in North Garo Hills, Meghalaya, NE India. Res J Recent Sci 2014;3:137-46.
Bhattacharyya PN, Tanti B, Barman P, Jha DK. Culture-independent metagenomic approach to characterize the surface and subsurface soil bacterial community in the Brahmaputra valley, Assam, North-East India, an Indo-Burma mega-biodiversity hotspot. World J Microbiol Biotechnol 2014;30:519-28.
Sahu J, Sen P, Choudhury MD, Dehury B, Barooah M, Modi MK, et al. Rediscovering medicinal plants’ potential with OMICS: Microsatellite survey in expressed sequence tags of eleven traditional plants with potent antidiabetic properties. OMICS 2014;18:298-309.
Chakraborty R, De B, Devanna N, Sen S. North-East India an ethnic storehouse of unexplored medicinal plants. J Nat Prod Plant Resour 2012;2:143-52.
Adhikari PP, Talukdar S, Borah A. Ethnomedicobotanical study of indigenous knowledge on medicinal plants used for the treatment of reproductive problems in Nalbari district, Assam, India. J Ethnopharmacol 2017;210:386-407.
Adhikari PP, Paul SB, Choudhury MD, Choudhury S. GC-MS studies on the steam-distillate of the medicinally important plant Cleome gynandra L. Int J Appl Res Stud 2014;3:1-4.
Aparadh VT, Mahamuni RJ, Karadge BA. Taxonomy and physiological studies in spider flower (Cleome species): A critical review. Plant Sci Feed 2012;2:25-46.
The Plant List. The Plant List, Version 1; 2010. Available from: http://www.theplantlist.org. [Last cited on Jan 01] [Last accessed on Aug 15].
Ravichandra B, Ram PS, Saritha C, Shankaraiah P. Anti-diabetic and anti-dyslipidemia activities of Cleome gynandra in alloxan induced diabetic rats. J Pharm Toxicol 2014;9:55-61.
Marshall DM, Muhaidat R, Brown NJ, Liu Z, Stanley S, Griffiths H, et al. Cleome, a genus closely related to Arabidopsis, contains species spanning a developmental progression from C(3) to C(4) photosynthesis. Plant J 2007;51:886-96.
Kori ML, Gaur K, Dixit VK. Investigation of immunomodulatory potential of Cleome gynandra Linn. Asian J Pharm Clin Res 2009;2:35-9.
Albarello N, Simões C, Rosas PF, Castro TC, Gianfaldoni MG, Callado CH, et al. In vitro propagation of Cleome spinosa (Capparaceae) using explants from nursery-grown seedlings and axenic plants. Vitro Cell Dev Biol Plant 2006;42:601-6.
Mishra SS, Moharana SK, Dash MR. Review on Cleome gynandra. Int J Res Pharm Chem 2011;1:681-9.
Chweya JA, Mnzava NA. Cat’s Whiskers, Cleome gynandra L. Vol. 11. Rome, Italy: Bioversity International; 1997.
Anbazhagi T, Kadavul K, Suguna G, Petrus AJ. Studies on pharmacognostical and in vitro antioxidant potential of Cleome gynandra Linn. leaves. Nat Prod Radian 2009;8:151-7.
Paul SB, Choudhury S, Adhikari PP. Isolated chemical components from spider weed, Cleome gynandra Linn: An overview. Assam Univ J Sci Technol 2012;10:166-73.
Misra RN, Dutt S. Chemical examination of cleoaie Pentaphylla Linn. Part Ii. oonstituents of the oil from. The seeds. Proc Natl Inst Sci India 1937;3:45.
Gupta RK, Chandra S, Mahadevan B. Chemical examination of seeds of Gynandropsis pentaphylla. Indian J Pharm 1968;30:127.
Saleh M. Phytochemical and botanical study of Gynandropsis sp. Part-I. Gynandropsis glucosinolates. Pharmazie 1976;31:818.
Hasapis X, MacLeod AJ, Moreau M. Glucosinolates of nine cruciferae and two Capparaceae species. Phytochemistry 1981;20:2355-8.
Ali AA, Sayed HM, Mesbah MK. Pharmacognosical study of Gynandropsis pentaphylla growing in Egypt, Pt. III. Bull Pharm Sci Assiut Univ 1987;10:74.
Jain AC, Gupta SM. Minor phenolic components of the seeds of Gynandropsis gynandra. J Nat Prod 1985;48:332-3.
Rastogi RP, Mehrotra BN. Cleome gynandra, Compendium of Indian Medicinal Plants. Vol. II, III, IV. New Delhi: CSIR; 1993. p. 112, 182, 193, 198.
Ragunathan V, Jaswant V, Sulochana N. Rutin from flowers of Cleome gyanandra Linn. J Ind Chem Soc 1997;74:821.
Das PC, Patra A, Mandal S, Mallick B, Das A, Chatterjee A. Cleogynol, a novel dammarane triterpenoid from Cleome gynandra. J Nat Prod 1999;62:616-8.
Lwande W, Ndakala A, Hassanali A, Moreka L, Nyandat E, Ndungu M, et al. Gynandropsis gynandra essential oil and its constituents as tick (Rhipicephalus appendiculatus) repellents. Phytochemistry 1999;50:401-5.
Roy S. Chemical and Biological studies on Cleome gynandra L. PhD Thesis. Silchar, India: Assam University; 2007. p. 2-23.
Ayurvedic Pharmacopoeia of India, Part I. Government of India, Ministry of Health and Family Welfare. Vol. I. New Delhi, India: Department of Indian Systems of Medicine and Homoeopathy; 2001.
Ayurvedic Pharmacopoeia of India. Part I, Government of India, Ministry of Health and Family Welfare. Vol. II. New Delhi, India: Department of Indian Systems of Medicine and Homoeopathy; 2001a.
Mule SN, Ghadge RV, Chopade AR, Bagul BA, Patil SB, Naikwade NS. Evaluation of anti-nociceptive and anti-inflammatory activity of leaves of Gynandropsis pentaphylla. J Herbal Med Toxicol 2008;2:41-4.
Narendhirakannan RT, Kandaswamy M, Subramanian S. Anti-inflammatory activity of Cleome gynandra L. on hematological and cellular constituents in adjuvant-induced arthritic rats. J Med Food 2005;8:93-9.
Narendhirakannan RT, Subramanian S, Kandaswamy M. Free radical scavenging activity of Cleome gynandra L. leaves on adjuvant induced arthritis in rats. Mol Cell Biochem 2005;276:71-80.
Bala A, Kar B, Haldar PK, Mazumder UK, Bera S. Evaluation of anticancer activity of Cleome gynandra on ehrlich’s ascites carcinoma treated mice. J Ethnopharmacol 2010;129:131-4.
Knekt P, Kumpulainen J, Järvinen R, Rissanen H, Heliövaara M, Reunanen A, et al. Flavonoid intake and risk of chronic diseases. Am J Clin Nutr 2002;76:560-8.
Arora S, Kumar G, Meena S. Gas chromatography-mass spectroscopy analysis of root of an economically important plant, Cenchrus ciliaris L. from thar desert, Rajasthan (India). Asian J Pharm Clin Res 2017;10:64.
Nagpal M, Aggarwal G, Jain UK, Madan J. Extraction of gum from Abelmoschus esculentus: Physicochemical peculiarity and antioxidant prepatent. Asian J Pharm Clin Res 2017;10:174.
Das A, Ahmed AB. Natural permeation enhancer for transdermal drug delivery system and permeation evaluation: A review. Asian J Pharm Clin Res 2017;10:5.
Published
How to Cite
Issue
Section
The publication is licensed under CC By and is open access. Copyright is with author and allowed to retain publishing rights without restrictions.