STEM CELLS: AN APPROACH FOR TREATMENT OF ATHEROSCLEROSIS

Vinod Kumar Jatav; Sunita Sharma

doi:10.22159/ajpcr.2018.v11i10.22690

Authors

Vinod Kumar Jatav Assistant Professor, Department of Biotechnology, Madhav Institute of Technology and Science, Gwalior â€“ 474005, Madhya Pradesh, India. http://orcid.org/0000-0002-2021-1505
Sunita Sharma Assistant Professor, Department of Biotechnology, Madhav Institute of Technology and Science, Gwalior â€“ 474005, Madhya Pradesh, India.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i10.22690

Keywords:

Stem cell, Cardiac diseases, Atherosclerosis, Bone marrow, Transplantation

Abstract

The contribution of stem cells to control atherosclerosis progression and vascular remodeling after injury in humans is established; however, many details are still unknown. The success with stem cell therapies in the treatment of hematological disorders over the past four decades enhanced our understanding of the physiology of vascular remodeling and motivated towards regenerative medicine and therapeutic restoration of the damaged organ. Stem cells isolated from bone marrow are currently being tested for their therapeutic potential in a variety of clinical conditions including cardiovascular injury, kidney failure, cancer, neurological, and bone disorders. The main focus of this review paper is to reveal the role of different types of stem cells such as embryonic stem cell, adult stem cell, smooth muscle progenitor cells, endothelial progenitor cells, mesenchymal stem cells, and vascular smooth muscle cells and find out possibility to use them for the treatment of atherosclerosis as well as to reduce atheroma formation.

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Author Biography

Vinod Kumar Jatav, Assistant Professor, Department of Biotechnology, Madhav Institute of Technology and Science, Gwalior â€“ 474005, Madhya Pradesh, India.

biotechnology

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