EVALUATING THE EFFECTIVENESS OF PHONOPHORESIS BY PIROXICAM AND DIMETHYL SULFOXIDE FOR WOMEN'S WITH OSTEOARTHRITIS KNEE JOINT

Authors

  • Monisha R Department of Physiotherapy, SRM College of Physiotherapy, Kancheepuram, Tamil Nadu, India. http://orcid.org/0000-0002-7126-1879
  • Manikumar M Department of Physiotherapy, Saveetha College of Physiotherapy, Chennai, Tamil Nadu, India.
  • Aparna Krishnakumar Department of Physiotherapy, Meenakshi College of Physiotherapy Chennai, Tamil Nadu, India.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i6.24615

Keywords:

Piroxicam, Dimethyl sulfoxide, Ultrasound therapy, Phonophoresis, Osteoarthritis

Abstract

Objective: Osteoarthritis (OA) is a progressive chronic disease with the loss of articular cartilage. In managing osteoarthritis, inadequate pain relief often occurs, particularly with a single non-steroidal anti-inflammatory drugs therapy.

Methods: A total of 50 participants were randomly allocated into three groups, received phonophoresis with piroxicam, dimethyl sulfoxide (DMSO), and ultrasound (US) therapy with aquasonic gel.

Results: On comparing, the baseline phonophoresis group with piroxicam showed significantly more pain reduction than the DMSO and US therapy. Enrolled patients in three groups have completed the study without any drawbacks.

Conclusion: This study showed that phonophoresis was superior to conventional US therapy in reducing pain in patients with symptomatic knee OA of a mild to moderate degree.

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Author Biography

Monisha R, Department of Physiotherapy, SRM College of Physiotherapy, Kancheepuram, Tamil Nadu, India.

SRM college of physiotherapy,

assistant professor

SRM university

References

Oka Dwicandra NM, Setiadi AA, Comparison of pain score in osteoarthritis patients treated with a combination of diacerein and meloxicam and meloxicam alone. Int J Pharm Pharm Sci 2017;9:69-73. (a) Kotlarz H, Gunnarsson CL, Fang H, Rizzo JA. Insurer and out-of pocket costs of osteoarthritis in the US: Evidence from national survey data. Arthritis Rheum 2009;60:3546-53.

Dunlop DD, Manheim LM, Song J, Chang RW. Arthritis prevalence and activity limitations in older adults. Arthritis Rheum 2001;44:212 21.

Zhang W, Moskowitz RW, Nuki G, Abramson S, Altman RD, Arden N, et al. OARSI recommendations for the management of hip and knee osteoarthritis, part II: OARSI evidence-based, expert consensus guidelines. Osteoarthritis Cartilage 2008;16:137-62.

Rutjes AW, Nuesch E, Sterchi R, Juni P. Therapeutic ultrasound for osteoarthritis of the knee or hip. Cochrane Database Syst Rev2010;1:CD003132.

Zhang Y, Jordan JM. Epidemiology of osteoarthritis. Clin Geriatr Med 2010;26:355-69.

Soni A, Kiran A, Hart DJ, Leyland KM, Goulston L, Cooper C, et al. Prevalence of reported knee pain over twelve years in a community-based cohort. Arthritis Rheum 2012;64:1145-52.

Zhang W, Doherty M. EULAR recommendations for knee and hip osteoarthritis: A critique of the methodology. Br J Sports Med 2006;40:664-9.

Tascioglu F, Kuzgun S, Armagan O, Ogutler G. Short-term effectiveness of ultrasound therapy in knee osteoarthritis. J Int Med Res 2010;38:1233-42.

Paliwal S, Mitragotri S. Therapeutic opportunities in biological responses of ultrasound. Ultrasonics 2008;48:271-8.

Chung JI, Barua S, Choi BH, Min BH, Han HC, Baik EJ, et al. Anti-inflammatory effect of low intensity ultrasound (LIUS) on complete freund’s adjuvant-induced arthritis synovium. Osteoarthritis Cartilage 2012;20:314-22.

Ateia YA, Al-Edanni MS, Al-Qurtas MS. Impact of metformin and serratiopeptidase in obese patients with knee osteoarthritis. Int J Pharm Pharm Sci 2018;10:37-41.

Deshpande MM, Patil CB. Heel pain and phonophoresis. J Indian Med Assoc 2010;108:365.

Yildiz N, Atalay NS, Gungen GO, Sanal E, Akkaya N, Topuz O, et al. Comparison of ultrasound and ketoprofen phonophoresis in the treatment of carpal tunnel syndrome. J Back Musculoskelet Rehabil 2011;24:39-47.

Ay S, DoÄŸan SK, Evcik D, BaÅŸer OC. Comparison the efficacy of phonophoresis and ultrasound therapy in myofascial pain syndrome. Rheumatol Int 2011;31:1203-8.

Nagrale AV, Herd CR, Ganvir S, Ramteke G. Cyriax physiotherapy versus phonophoresis with supervised exercise in subjects with lateral epicondylalgia: A randomized clinical trial. J Man Manip Ther 2009;17:171-8.

Silveira PC, Victor EG, Schefer D, et al. Effects of therapeutic pulsed ultrasound and dimethylsulfoxide (DMSO) phonophoresis on parameters of oxidative stress in traumatized muscle. Ultrasound Med Biol 2010;36:44-50.

Vlak T. Comparative study of the efficacy of ultrasound and sonophoresis in the treatment of painful shouder syndrome. Reumatizam 1999;46:5 11.

Kozanoglu E, Basaran S, Guzel R, Guler-Uysal F. Short term efficacy of ibuprofen phonophoresis versus continuous ultrasound therapy in knee osteoarthritis. Swiss Med Wkly 2003;133:333-8.

Goraj-Szczypiorowska B, Zajac L, Skalska-Izdebska R. Evaluation of factors influencing the quality and efficacy of ultrasound and phonophoresis treatment. Ortop Traumatol Rehabil 2007;9:449-58.

Published

07-06-2018

How to Cite

R, M., M. M, and A. Krishnakumar. “EVALUATING THE EFFECTIVENESS OF PHONOPHORESIS BY PIROXICAM AND DIMETHYL SULFOXIDE FOR WOMEN’S WITH OSTEOARTHRITIS KNEE JOINT”. Asian Journal of Pharmaceutical and Clinical Research, vol. 11, no. 6, June 2018, pp. 329-31, doi:10.22159/ajpcr.2018.v11i6.24615.

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Original Article(s)