MANIA INDUCED BY STEROID-ADULTERATED HERBAL MEDICINE: A CASE REPORT

Authors

  • Lydia Lay Yen Gan Department of Pharmacy, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia. http://orcid.org/0000-0002-1005-3777
  • Luke Sy-cherng Woon Department of Psychiatry, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
  • Maria Ulfaahmad Zawawi Department of Psychiatry, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
  • Marhani Midin Department of Psychiatry, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i5.25640

Keywords:

Adulteration, Chinese Proprietary Medicine, Dexamethasone, Herbal medicine, Mania, Steroid

Abstract

Traditional herbal medicines are generally perceived as natural and safe. Nonetheless, adulteration of such complementary products, including Chinese Proprietary Medicines with undeclared drugs, notably steroids, is a recognized problem. While there are many accounts of Cushing's syndrome due to steroid content in traditional medicines, psychiatric complications caused by the similar insults are not reported throughout the literature. We report a case of acute mania after the short-term use of steroid-adulterated herbal product in a previously healthy young male. It shows that psychiatric complications can occur in such a scenario without the physical and metabolic features of Cushing's syndrome, and pharmacodynamic interaction between the herbal ingredient and adulterant is a possible factor. The case also highlights the need for awareness of culturally influenced health product consumption and its potential effects on clinical conditions, as well as the important role of a robust surveillance system for such products.

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Author Biography

Lydia Lay Yen Gan, Department of Pharmacy, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.

Department of Pharmacy and Department of Psychiatry

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Published

01-05-2018

How to Cite

Gan, L. L. Y., L. S.- cherng Woon, M. U. Zawawi, and M. Midin. “MANIA INDUCED BY STEROID-ADULTERATED HERBAL MEDICINE: A CASE REPORT”. Asian Journal of Pharmaceutical and Clinical Research, vol. 11, no. 5, May 2018, pp. 10-12, doi:10.22159/ajpcr.2018.v11i5.25640.

Issue

Section

Case Study(s)