CORRELATION OF NON-HIGH-DENSITY LIPOPROTEIN CHOLESTEROL WITH LIPOPROTEIN(A) IN DIABETIC PATIENTS
DOI:
https://doi.org/10.22159/ajpcr.2018.v11i9.26278Keywords:
Lipoprotein(a), Non-high-density lipoprotein, Coronary artery diseaseAbstract
Objective: The objective of this study is to estimate the level of lipoprotein(a) and lipid profile, especially non-high-density lipoprotein cholesterol (non-HDL-C) in diabetic patients, and to correlate the same with healthy controls (non-diabetics).
Methods: A total of 30 non-diabetic subjects and 30 diabetic patients were included in the study. Lipoprotein(a) (Lp[a]) was estimated by immunoturbidimetry and the other parameters by their respective methods in biochemistry auto-analyzer.
Result: From the study, it was found that both Lp(a) and non-HDLC were increased in diabetics when compared to the non-diabetic controls. It was also evident that there is a positive correlation of Lp(a) levels with non-HDL C.
Conclusion: Lp(a) and non-HDL C are responsible for atherogenic events in uncontrolled diabetic patients, leading to risks such as coronary artery disease.
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