CONNECTION APPROACHES BETWEEN TRADITIONAL AND MODERN PHARMACOLOGICAL PROFILE OF SHOREA ROBUSTA GAERTN. F.: A REVIEW

Manish Pal Singh; Ravi Kumar

doi:10.22159/ajpcr.2018.v11i9.26978

Authors

Manish Pal Singh Department of Pharmacology, Rajiv Academy for Pharmacy, Mathura â€“ 281 001, Uttar Pradesh, India.
Ravi Kumar Department of Pharmacology, Rajiv Academy for Pharmacy, Mathura â€“ 281 001, Uttar Pradesh, India.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i9.26978

Keywords:

Shorea robusta, Tannins, Phenols, Wound healing, Antidiabetic

Abstract

Shorea robusta is regarded as an important medicine in Ayurveda. S. robusta Gaertn. f. belongs to family Dipterocarpaceae, and traditionally, it is used to treat wounds, ulcers, leprosy, cough, gonorrhea, earache, and headache and many more. The use of different parts of this plant such as leaves, resin, and bark as a medicament for the treatment of various conditions is well documented in literature. It is the rich source of flavonoids, saponins, steroids, tannins, phenols, etc. mainly triterpenoids, which play the prominent role for their therapeutic potential in the drug. These compounds are believed to be responsible for the pharmacological activities of plant extract. The present review clarified the main active ingredients and pharmacological effects of S. robusta as a promising plant as a result of effectiveness and safety. Further studies should be carried out this plant to discover the unrevealed part of it which may serve for the welfare of humankind.

Downloads

Download data is not yet available.

Author Biography

Manish Pal Singh, Department of Pharmacology, Rajiv Academy for Pharmacy, Mathura â€“ 281 001, Uttar Pradesh, India.

Manish Pal singh, ASSOCIATE PROFESSOR, Department of Pharmacology, Rajiv Academy for Pharmacy, NH#2, Chattikara, mathura, UP-281001

References

The Wealth of India. Raw Materials. Vol. X. New Delhi: CSIR. 1976. p. 175.

Croom EM. Documenting and evaluating herbal remedies. Econ Bot 1983;37:13-27.

The Ayurvedic Pharmacopoeia of India. Ministry of Health, Government of India. New Delhi: The Ayurvedic Pharmacopoeia of India; 2001.

Sharma PC, Yelne MB, Dennis TJ. Database on Medicinal Plants Used in Ayurveda. 3rd ed. New Delhi. India: Central Council for Research in Ayurveda and Siddha; 2005. p. 282-4.

Chandel KP, Shukla G, Sharma N. Biodiversity in Medicinal and Aromatic Plants in India: Conservation and Utilization. New Delhi, India: National Bureau of Plant Genetic Resources; 1996.

Chitale VS, Behra MD. Can the distribution of Sal (Shorea robusta Gaertn.f.) shift in the northeastern direction in India due to changing climate? Curr Sci India 2012;102:1126-35.

Patwardhan B, Warude D, Pushpangadan P, Bhatt N. Ayurveda and traditional Chinese medicine: A comparative overview. Evid Based Complement Alternat Med 2005;2:465-73.

Misra B, Vaisya R. Tailavarga in Bhavaprakasha nighantu. Part I, B, The Kashi Sanskrit Series. Varanasi, India: Chaukhumba Bharati Academy; 1963. p. 779.

Patwardhan B, Chopra A, Vaidya AD. Herbal remedies and the bias against Ayurveda. Curr Sci 2003;84:1165-6.

Vaidya RA, Vaidya AD, Patwardhan B, Tillu G, Rao Y. Ayurvedic pharmacoepidemiology: A proposed new discipline. J Assoc Physicians India 2003;51:528.

Bursal E, GulÃ§in I. Polyphenol contents and in vitro antioxidant activities of lyophilized aqueous extract of kiwifruit (Actinidia deliciosa). Food Res Int 2011;44:1482-9.

Morikawa T, Chaipech S, Matsuda H, Hamao M, Umeda Y, Sato H, et al. Antidiabetogenic oligostilbenoids and 3-ethyl-4-phenyl-3,4- dihydroisocoumarins from the bark of Shorea roxburghii. Bioorg Med Chem 2012;20:832-40.

Evans WC. Trease and Evans Pharmacognosy. London: Harcourt Publisher Ltd.; 2002. p. 472-4.

Kokate CK, Purohit AP. Pharmacognosy. 38th ed. Pune, India. Nirali Prakashan; 2005. p. 600-4.

Tondon N, Sharma GM. Quality Standards of Indian Medicinal Plants. New Delhi: Indian Council of Medical Research; 2003. p. 207-9.

Kar A. Pharmacognosy and Biotechnology. 2nd ed. New Delhi. India: New Age International Private Ltd.; 2007.

Khare CP. Indian Medicinal Plants. An Illustrated Dictionary. New York: Springer International ed. 1989. p. 29.

Chunekar KC, Pandey GS. Bhavaprakasha Nighantu. Varanasi: Chaukhambha Bharati Academy; 2010. p. 508-9.

Sastry JL. Dravyaguna Vijnana. Varanasi: Chaukhambha Orientalia 2005. p.78-6.

Yaseen Khan M, Ali SA, Pundarikakshudu K. Wound healing activity of extracts derived from Shorea robusta resin. Pharm Biol 2016;54:542-8.

Dunphy JE, Edwards LC, Udupa KN. Wound healing; A new perspective with particular reference to ascorbic acid deficiency. Ann Surg 1956;144:304-17.

Erhlich HP, Hunt TK. Effect of cortisone and anabolic steroids on tensile strength of healing wound. Ann Surg 1969;170:203-6.

Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-75.

Sahasrabudhe PB, Dhondge RD, Panse N. Raal ointment compared with 1% silver sulfadiazine cream for the treatment of second degree burns. Indian J Burns 2014;22:37-42.

Mukherjee H, Ojha D, Bharitkar YP, Ghosh S, Mondal S, Kaity S, et al. Evaluation of the wound healing activity of Shorea robusta, an Indian ethnomedicine, and its isolated constituent(s) in topical formulation. J Ethnopharmacol 2013;149:335-43.

Mukherjee PK, Mukherjee K, Rajesh Kumar M, Pal M, Saha BP. Evaluation of wound healing activity of some herbal formulations. Phytother Res 2003;17:265-8.

Nayak S, Nalabothu P, Sandiford S, Bhogadi V, Adogwa A. Evaluation of wound healing activity of Allamanda cathartica. L. And Laurus nobilis. L. Extracts on rats. BMC Complement Altern Med 2006;6:12.

Prasad V, Dorle AK. Evaluation of ghee based formulation for wound healing activity. J Ethnopharmacol 2006;107:38-47.

Wani TA, Chandrashekar HH, Kumar D, Prasad R. Wound healing activity of ethanolic extract of Shorea robusta gaertn F. Resin. Indian J Exp Boil 2012;50:277-81.

Wani TA, Chandrasekhara HH, Kumar D. Anti-inflammatory and antipyretic activities of the ethanolic extract of Shorea robusta Gaertn.f. Resin. Ind J Biochem Biophys 2012;49:963-7.

Datta HS, Mitra SK, Patwardhan B. Wound healing activity of topical application forms based on Ayurveda Hindawi publishing corporation. Evid Based Complementary Altern Med 2011;2011. Article ID: 134378, 10 Pages.

Chithra P, Sajithlal GB, Chandrakasan G. Influence of Aloe vera on collagen turnover in healing of dermal wounds in rats. Indian J Exp Biol 1998;36:896-901.

Nayak BS, Sandiford S, Maxwell A. Evaluation of the wound-healing activity of ethanolic extract of Morinda citrifolia L. Leaf. Evid Based Complementary Altern Med 2009;6:356-6.

Sumitra M, Manikandan P, Suguna L. Efficacy of Butea monosperma on dermal wound healing in rats. J Biochem Cell Biol 2005;37:566-73.

Hota RK, Bapuji M. Triterpenoids from the resin of Shorea robusta. Phytochemistry 1993;32:466-8.

Sushma RK, Sreedhara RP, Nayak JP, Hemalatha B, Keerthana P, Kumar MB. Biomechanical, biochemical and histological evidences for wound healing properties of Indian traditional medicines. Int J Pharm Pharm Sci 2015;7:163-171.

Vashisht S, Singh MP, Chawla V. In-vitro antioxidant and antibacterial activity of methanolic extract of Shorea robusta Gaertn. F. resin. Int J Pharm Phytopharm Res 2016;6:68-71.

Banerjee RP, Banerjee S, Sarkar P, Pradhan NK. Phytochemical analysis and antimicrobial activity of natural resin (lal dhuna) from Shorea robusta (sal). Int J Pharm Sci Health Care 2014;4:52-60.

Adlakha MK, Bhargava AK, Kapoor R, Sharma LN, Singh C. Ayurvedic medicinal plant Shorea robusta (shala). Innov J Ayurvedic Sci 2014;18-21.

Murthy KS, Lakshmi N, Ramulu DR. Biological activity and phytochemical screening of the oleoresin of Shorea robusta Gaertn. F. Trop Subtrop Agroecosyst 2011;14:787-91.

Duddukuri GR, Rao DE, Kaladhar DS, Sastry N, Rao KK, Chaitanya KK, et al. Preliminary studies on in vitro antibacterial activity and phytochemical analysis of aqueous crude extract of Shorea robusta floral parts. Int J Curr Res 2011;3:21-3.

Smita HG, Chintamani UB. Study of antibacterial activity of resins of Boswellia serrata roxb ex colebr., commiphora mukul (hooks ex-stocks) engl., Gardenia resinifera roth. And Shorea robusta gaertn. Int J Pharm Pharm Sci 2016;8:29-31.

Abdallah EA, Khalid AS, Ibhrahim N. Antibacterial activity of oleo-gum resins of Commiphora molmol and Boswellia papyrifera against methicillin-resistant Staphlococcus aureus (MRSA). Sci Res Essay 2009;4:351-6.

Mahadlek J, Phachamud T, Wessapun C. Antimicrobial studies of Sonneratia caseolaris using different agar diffusion method. Res J Pharm Biol Chem Sci 2012;3:404-310.

Rajendra CE, Kumar DH, Yeshoda SV, Nadaf MA, Hanumanthraju N. Comparative evaluation of antimicrobial activities of methanolic extract of Curcuma longa and Boswellia serrata. Int J Res Pharm Chem 2013;3:534-6.

Ishnava KB, Mahida YN, Mohan JS. In vitro assessments of antibacterial potential of Commiphora wightii (Arn.) Bhandari. Gum extract. J Pharmacogn Phytother 2010;2:91-6.

Vimala G, Gricilda Shoba F. A review on antiulcer activity of few Indian medicinal plants. Int J Microbiol 2014;2014:519590.

Muthu S, Anusuya N, Bhuvaneswari P. Antiulcerogenic effect of resin from Shorea robusta gaertn. F. On experimentally induced ulcer models. Int J Pharm Pharm Sci 2013;5:269-72.

Goel RK, Sairam K. Antiulcer drugs from indigenous sources with emphasis on Musa sapientum, Tamra bhasna, Asparagus racemosus and Zingiber officinale. Indian J Pharmacol 2002;34:100-10.

Hiruma-Lima CA, Gracioso JS, Bighetti EJ, Grassi-Kassisse DM, Nunes DS, Brito AR, et al. Effect of essential oil obtained from croton cajucara benth. On gastric ulcer healing and protective factors of the gastric mucosa. Phytomedicine 2002;9:523-9.

Kalra P, Sharma S, Suman, Kumar S. Antiulcer effect of the methanolic extract of Tamarindus indica seeds in different experimental models. J Pharm Bioall Sci 2011;3:236-41.

Andrikopoulos NK, Kaliora AC, Assimopolou NA, Papapeorgiou VP. Biological activity of some naturally occurring resins, gums and pigments against in vitro LDL oxidation. Phytother Res 2003;7:501-7.

Suzuki Y, Ishihara M, Segami T, Ito M. Anti-ulcer effects of antioxidants Quercetin alpha-tocopherol nifedipine and tetracycline in rats. Jpn J Pharmacol 1998;78:435-41.

Mathavi P, Nethaji S. In-vitro antioxidant activity of Shorea robusta leaf extract. Int J Res Biochem Biophys 2014;4:22-6.

Subramanian R, Subbramaniyan P, Raj V. Antioxidant activity of the stem bark of Shorea roxburghii and its silver reducing power. Springerplus 2013;2:28.

Amarowicz R, Pegg RB, Moghaddam PR, Barl B, Weil JA. Free radical-scavenging capacity and antioxidant activity of selected plant species from the Canadian prairies. Food Chem 2004;84:551-62.

Nikfardjam MS, Gy L, Dietrich H. Resveratrol-derivatives and ant oxidative capacity in wines made from botrytized grapes. Food Chem 2006;96:74-9.

Rice-Evan CA, Miller N. Antioxidant property of phenolic compounds. Trends Plant Sci 1997;2:152-9.

Soares JR, Dinis TC, Cunha AP, Almeida LM. Antioxidant activities of some extracts of Thymus zygi. Free Rad Res 1997;26:469-78.

Sotheeswaran S, Pasupathy V. Distribution of resveratrol oligomers in plants. Phytochemistry 1993;32:1083-92.

Gokulakrishnan K. Bark extract of Shorea robusta on modulation of immune response in rats. Int J Recent Sci Res 2012;3:693-7.

Kanjwani DG, Marathe TP, Chiplunkar SV, Sathaye SS. Evaluation of immunomodulatory activity of methanolic extract of piper betel. Scand J Immunol 2008;67:589-93.

Kore KJ, Shete RV, Kabra MP, Rachhadiya RM, Attal AR. Immunomodulatory activity of Balanite roxburghi. J Pham Res Health Care 2011;3:63-7.

Lily G, Padwad Y, Singh R, Karan D, Chanda S, Chopra MK, et al. Anti-inflammatory activity of Seabuckthorn (Hippophae rhamnoides) leaves. Int Immunopharmacol 2005;5:1675-84.

Patwardhan B, Kalbag D, Patki PS, Nagsampagi BA. Search of immunomodulatory agents: A review. Indian Drugs 1990;28:348-58.

Summerfield A, SaalmÃ¼ller A. Interleukin-2 dependent selective activation of porcine gamma delta T lymphocytes by an extract from the leaves of Acanthospermum hispidum. Int J Immunopharmacol 1998;20:85-98.

Nainwal P, Bhatt R, Nanda D, Saini P. Screening of inâ€“vitro anti-inflammatory activity of aqueos extract of leaves of Shorea robusta. Int J Pharmacol Screen Method 2013;3:43-5.

Chattopadhayay D. Inhibition of TNF-Î± and Inos expression by Shorea robusta L: An ethnomedicine used for anti-inflammatory and analgesic activity. Evid Based Complement Altern Med 2012;2012. Article ID: 129152, 14 Pages.

Jyothi G, Carrey WM, Krishna MG. Antinociceptive and anti-inflammatory activity of methanolic extract of leaves of Shorea robusta. Pharmacologyonline 2008;1:9-19.

Jyothi G. Antinociceptive and anti-inflammatory activity of methanolic extract of leaves of Shorea robusta. Pharmacologyonline 2008;1:11-2.

Wani TA, Chandrashekhara HH, Kumar D. Analgesic activity of ethanolic extract of Shorea robusta resin in experimental animals. Indian J Pharmacol 2012;44:493-9.

Wani TA, Chandrashekara HH, Kumar D, Prasad R, Sardar KK, Kumar D, et al. Anti-inflammatory and antipyretic activities of the ethanolic extract of Shorea robusta gaertn. F. Resin. Indian J Biochem Biophys 2012;49:463-7.

Supriya K. Antiobesity activity of Shorea robusta G. Leaves extract on high fat diet induced obesity in albino rats Res. J Pharm Biochem Sci 2012;3:542-54.

Sudha S, Prasanna G. Antidiabetic and antihyperlipidemic effect of ethanolic extract of Shorea robusta gaertn.F. In alloxan induced rats. J Med Toxicol 2013;7:67-72.

Ravichandiran V, Satish PV, Yadav BV. Attenuation of biochemical parameters of Shorea robusta leaves in streptozotocin induced diabetic rats. World J Pharm Res 2015;4:1662-72.

Kalaiselvan A, Gokulkrishan K. Bark extract of Shorea robusta on modulation of immune response in rats. Int J Recent Sci Res 2012;3:693-7.

Hobbs C. Valerian monograph. Herb Gram 1989;21:19-34.

Grieve M. In: Leyel CF, editor. A Modern Herbal. London: Tiger Books International; 1976. p. 912.

Benigni R, Capra C, Cattorini P. Piante Medicinali Chimica Farmacologia E Terapia. Vol. 1. Milano: Inverni & Della Beffa; 1971. p. 730.

Ellingwood F, Lloyd JU. A Systematic Treatise on Materia Medica and Therapeutics. Chicago: Chicago Med Press; 1900. p. 706.

Scudder JM. Specific Medications and Specific Medicines. 15th ed. Cincinnati: Scudder Bros; 1903, 1985. p. 432.

Fleming T. PDR or Herbal Medicines. Montvale, NJ: Medical Economics Company, Inc.; 1998.

Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-Care Professionals. London: The Pharmaceutical Press; 1996.

Peralta CM, Henestrosa C, Gil RA, FernÃ¡ndez LP, Acosta G. Novel spectrofluorimetric method for boldine alkaloid determination in herbal drugs and phytopharmaceuticals. Spectrochim Acta A Mol Biomol Spectrosc 2017;184:101-8.