DEVELOPMENT OF DRYING PROTOCOL FOR WITHANIA SOMNIFERA ROOTS

Authors

  • Soni S Department of School of Pharmacy, Suresh Gyan Vihar University, Jaipur, Rajasthan, India.
  • Himmat Singh Chawra Department of School of Pharmacy, Suresh Gyan Vihar University, Jaipur, Rajasthan, India.
  • Sharma Rk Department of School of Pharmacy, Suresh Gyan Vihar University, Jaipur, Rajasthan, India.
  • Garg R Department of B.R. Nahata College of Pharmacy, Mandsaur, Madhya Pradesh, India.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i10.28402

Keywords:

Withania somnifera, Shade drying, Moisture content, Withanolide A

Abstract

Objective: This experiment was conducted to develop a drying protocol for Withania somnifera roots (during the year 2009–2010 under the National Medicinal Plants Board project, B.R. Nahata College of Pharmacy-Scientific Institute of Research Organization, Mandsaur [M.P.]).

Methods: The roots of Withania were harvested and cut into different sizes (2–4 inches) and subjected into sun drying, shade drying, and hot air oven drying in temperature ranging from 40°C to 60°C. The temperature for sun drying ranging from 32°C to 42°C during daytime, and in night hours, the samples were kept in plastic covers to prevent reabsorption of moisture. In shade drying, the pieces of roots were kept in shade (proper air flowing place) at normal climatic temperature. Moreover, in hot air oven drying method/mechanical drying method, the pieces of roots were kept at 50°C, 55°C, and 60°C, respectively. The samples were weighed, and the moisture content of the samples was taken at regular intervals until the standard moisture content of the dried roots was obtained that is mentioned in literature (10–5%).

Result: The result revealed that hot air oven drying of roots took the lowest time (12 h), while sun drying method took 24 h for drying. The alkaloid content, namely, Withanolide A was significantly influenced by different methods of drying. The highest alkaloid content (0.010%) was observed in sun drying and hot air oven drying with 0.021.abc% as compared to shade drying with 0.009% Withanolide A.

Conclusion: It may be concluded that sun drying and hot air oven drying are suitable methods for drying W. somnifera roots.

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Author Biographies

Soni S, Department of School of Pharmacy, Suresh Gyan Vihar University, Jaipur, Rajasthan, India.

School of pharmacy, Suresh Gyan Vihar University, Jagatpura, Jaipur

ASST PROFESSOR

Himmat Singh Chawra, Department of School of Pharmacy, Suresh Gyan Vihar University, Jaipur, Rajasthan, India.

School of pharmacy, Suresh Gyan Vihar University, Jagatpura, Jaipur

ASST PROFESSOR

References

Desilva T. Chapter-industrial utilization of medicinal plants in developing countries. Book of Medicinal Plants for Forest Conservation and Health Care. Rome, Italy: Food and Agriculture Organization of the United Nations; 2005.

Akowuah GA, Zhari I, Norhayati I, Maram A. HPLC and HPTLC densitometric determination of andrographolides and antioxidant potential of Andrographis paniculata. J Food Compost Anal 2006;19:118-26.

Bhan MK, Dhar AK, Khan S, Lattoo SK, Gupta KK, Choudhary DK, Screening and optimization of Andrographis paniculata (Burm.f.) nees for total andrographolide content, yield and its components. Sci Hortic 2006;107:386-91.

Alwakeel SS, Microbial and heavy metal contamination in herbal medicines. Res J Microbiol 2008;3:683-91.

Misra L, Mishra P, Pandey A, Sangwan RS, Sangwan NS, Tuli R, et al. Withanolides from Withania somnifera roots. Phytochemistry 2008;69:1000-4.

Alwadi HM, Baka ZA. Microorganisms asssociated with Withania somnifera leaves. Microbiol Res 2001;156:303-9.

Jose KP and Joy CM, Postharvest processing of spices in relation to export quality. Everyman’s Sci 2004;39:230-5.

Bachmann J, Earles R. Postharvest Handling of Fruits and Vegetables. Washington, D.C: NCAT agriculture specialists published, ATTRA Publication #IP116; 2000.

Kulkarni SK, Dhir A. Withania somnifera: An Indian ginseng. Prog Neuropsychopharmacol Biol Psychiatry 2008;32:1093-105.

Evans WC, Pharmacognosy. Noida, U P, India; Published by Elsevier (India) Pvt Ltd.; 2007. p. 15, 64.

Anonymous. Available from: http://www.del.icio.us/dig/reddit/furl.com. How to Dry Fruits and Vegetables. 2009.

Khan TA, Gohel1 AK, Mallya R. Svkm’s standardisation and HPTLC method development of marketed ayurvedic formulation–balarishta. Int J Pharm Pharm Sci 2016;8:201-9.

Jena1 S, Jena RC, Bho R, Agarwal1 K, Sarangi A, Sahu PK, Mishra S. A comparative study of the anti-oxidative and anti-diabetic potential of in vitro and in vivo root and leaf extracts of Withania somnifera on streptozotocin induced diabetic rats. Int J Pharm Pharm Sci 2016;8:85-91.

Anonymous. Elgar J. Hort Research, Mt Albert, Hort FACT-Carnations-Harvesting and Post-harvest Practices for Commercial Production, Vol. 6; 1998. Available from: http://www.hortnet.co.nz/copy.html.

Anonymous. Rashmin, an Introduction to Analytical Method Development for Pharmaceutical Formulations. 2008. Available from: http://www.pharmainfo.net.

Araya OS, Ford JH, Wort J. Reported Hypericum perforatum is a Perennial Herbaceous Plant, Air Drying of the Level of Hypericin by up to 80% Most Likely as a Result of Oxidation. (United States Patent 6128831), Process for Drying Medicinal Plants; 1981, 1999.

Arogba SS, Ugwu FM, Abu JD. The effects of sun-drying surfaces and packaging materials on the storability of cowpea (Vigna unguiculata) seed. Plant Foods Hum Nutr 1999;53:113-20.

Badger WL, Banchero J. Introduction to Chemical Engineering. Ch. 10. Drying, Edition. New Delhi: Published by TATA McGraw-Hill Company Ltd.; 1997. p. 469-517.

Bala BK, Janjai S. Solar Drying of Fruits, Vegetables, Spices, Medicinal Plants and Fish Developments and Potentials, International Solar Food Processing Conference; 2009.

Rawlins EA, editor. Bentley’s, Text Book Pharmaceutics. 8th ed. New Delhi: Elsevier Private Ltd.; 1992. p. 186-94.

Blank AF, Filho JL, Péricles BA, Ehlert PA, Melo AS, Cavalcanti SC, et al. Influence of the harvesting time, temperature and drying period on basil (Ocimum basilicum L.) essential oil Revista brasileira de farmacognosia. Braz J Pharmacogn 2006;16:24-30.

Attorney JJ, Moore P, Lempio W, Strabala. Method for Drying and Preserving Plant Material. (United States Patent No 3861053), February; 1972.

Cooper JW. Cooper and Gunn’s C, Tutorial pharmacy. 1st ed. London: CBS Publishers and Distributors; 2005. p. 6, 270.

Demir V, Gunhan T, Yagcioglu AK, Degirmencioglu A. Mathematical modelling and the determination of some quality parameters of air-dried bay leaves. Biosyst Eng 2004;88:325-35.

Lemos DR. Influence of Drying Air Temperature on the Essential Oil Content from Melaleuca alternifolia Cheel. Brazil: International Conference of Agricultural Engineering XXXVII Congresso Brasileiro de Engenharia Agrícola; 2008.

Timothy D, Alex YN, Kim H, Christine HS. (US Patent No 6128831) - Process for Drying Medicinal Plants. US Patent Issued on October 10; 2000.

Dwivedi SK, Ahmed Z. Studies on post harvest management and value addition in seabuckthorn (Hippopheae rhamnoides L.). Division of Horticulture and Post Harvest Technology. India: Field Research Laboratory; 2003.

Ganzera M, Choudhary MI, Khan IA Quantitative HPLC analysis of withanolides in Withania somniferum. Fitoterapia 2003;74:68-76. Available from: http://www.elsevier.com/locate/fitote.

Goel AK, Kumar R, Mann SS, Post Harvest Management and Value Addition. New Delhi: DAYA Publishing House; 2007.p. 119-33, 60-72.

Gupta DP, editor. The Herbs Habitat, Morphology and Pharmacognosy of Medicinal Plants. 1st ed. ???: ???; 2008. p. 46-9, 464-8.

Indian Drug Manufacturer’s Association. Indian Herbal Pharmacopoeia Revised New Edition. Andrographis paniculata (Burm f.) Wall. Ex Nees. ???: Indian drug Manufacturer’s Association; 2002. p. 57-66.

Indian Drug Manufacturer’s Association. Indian Herbal Pharmacopoeia Revised New Edition. Withania somnifera (Linn.). Published by Indian drug Manufacturer’s Association; 2002. p. 467-74.

Published

07-10-2018

How to Cite

S, S., H. S. Chawra, S. Rk, and G. R. “DEVELOPMENT OF DRYING PROTOCOL FOR WITHANIA SOMNIFERA ROOTS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 11, no. 10, Oct. 2018, pp. 86-92, doi:10.22159/ajpcr.2018.v11i10.28402.

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Original Article(s)