A DEEP INSIGHT ON DIABETIC NEUROPATHY: THE SILENT COMPLICATION OF DIABETES, WITH INPUTS ON ITS CAUSES, DIAGNOSIS, PATHWAYS, AND TREATMENTS

Authors

  • Nikita Saraswat Department Pharmacy, Pranveer Singh Institute of Technology, Kanpur, Uttar Pradesh, India.
  • Phool Chandra Department of Pharmacy, School of Pharmaceutical Sciences, IFTM University, Moradabad, Uttar Pradesh, India.
  • Neetu Sachan Department of Pharmacy, School of Pharmaceutical Sciences, IFTM University, Moradabad, Uttar Pradesh, India.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i12.28447

Keywords:

Diabetic neuropathy, Diabetes mellitus, Distal symmetric polyneuropathy, Chronic complications, Antidepressant, Ethnomedicine, Pathways of diabetic neuropathy

Abstract

Background: The incidence of diabetic neuropathy (DNP) is a prominent complication for people suffering from diabetes. DNP is a common complication in patients suffering from diabetes, and it is affecting approximately more than 50% of the population where the nerves are affected by high glucose levels.

Objective: The aim of the review paper is to inspect the complications, causes, diagnosis, pathogenesis, treatments, pathways, and management of DNP as all these factors play important role in the management of DNP. This paper also aims to identify the potential cures and the side effects if any associated with the commonly used treatments in conditions of DNP.

Methods: The data collected for reviewing was by studying the published researchers from PubMed, Web of Science, Medline, Science Direct, Excerpta Medica Database, Cochrane, Elton B. Stephens Company (EBSCO), and Google open access publications from the year 1995–2017.

Results: We have concluded on an interpretation that the drugs for treating DNP are managing the pain and controlling glucose levels but are reportedly causing major side effects. Hence, attention must be given to the potential risk factors for neuropathy and development of formulations with minimal side effects and a potential cure. We have focused on the recent researches, emerging problems, and techniques for identifying the patients suffering from DNP.

Conclusion: The incidence of DNP is a prominent complication for people suffering from diabetes. Although the treatment available currently focusses on the pain management in DNP, attention must be given to the potential risk factors for neuropathy and development of formulations with minimal side effects and a potential cure.

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Author Biographies

Nikita Saraswat, Department Pharmacy, Pranveer Singh Institute of Technology, Kanpur, Uttar Pradesh, India.

To work enthusiastically in your esteemed University in field of Pharmacy who is committed to safeguarding and promoting the levels of healthcare and education.

  • Currently working as a Assistant Professor Pharmacy in PSIT, Kanpur (Pranveer Singh Institute of Technology, Kanpur)
  • Worked as a Assistant Professor Pharmacy in SRMSCET (Shri Ram Murti

Smarak College of Engineering and Technology, Bareilly)

 

  • Worked as Assistant Professor Pharmacy in NIET (Noida Institute of Engineering Technology) Greater Noida

Nikita Saraswat

Assistant Professor

Department Pharmacy

Pranveer Singh Institute of Technology

+91-9621980069

 

Phool Chandra, Department of Pharmacy, School of Pharmaceutical Sciences, IFTM University, Moradabad, Uttar Pradesh, India.

M.Pharm, Ph.D. - Pharmacology

School of Pharmaceutical Sciences, IFTM University, Moradabad, India 

Neetu Sachan, Department of Pharmacy, School of Pharmaceutical Sciences, IFTM University, Moradabad, Uttar Pradesh, India.

M.Pharm. Ph.D 

School of Pharmaceutical Sciences, IFTM University, Moradabad, India

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Published

07-12-2018

How to Cite

Saraswat, N., P. Chandra, and N. Sachan. “A DEEP INSIGHT ON DIABETIC NEUROPATHY: THE SILENT COMPLICATION OF DIABETES, WITH INPUTS ON ITS CAUSES, DIAGNOSIS, PATHWAYS, AND TREATMENTS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 11, no. 12, Dec. 2018, pp. 112-9, doi:10.22159/ajpcr.2018.v11i12.28447.

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