ANTIBACTERIAL ACTIVITY OF POLYSCIAS SCUTELLARIA FOSBERG AGAINST ACINETOBACTER SP.

Dela Rosa; Yuniwaty Halim; Natania Kam; Marcelia Sugata; Ariela Samantha

doi:10.22159/ajpcr.2019.v12i1.30270

Authors

Dela Rosa Department of Biology, Universitas Pelita Harapan, Tangerang, Indonesia.
Yuniwaty Halim Department of Food Technology, Universitas Pelita Harapan, Tangerang, Indonesia.
Natania Kam Department of Food Technology, Universitas Pelita Harapan, Tangerang, Indonesia.
Marcelia Sugata Department of Biology, Universitas Pelita Harapan, Tangerang, Indonesia.
Ariela Samantha Department of Biology, Universitas Pelita Harapan, Tangerang, Indonesia.

DOI:

https://doi.org/10.22159/ajpcr.2019.v12i1.30270

Keywords:

Acinetobacter sp, Antibacterial, Nothopanax scutellarium, Polyscia s scutellaria

Abstract

Objective: Polyscias scutellaria Fosberg as one of the indigenous plants from Indonesia has been used as traditional medicines for several ailments, such as reduce body odor. However, there is no scientific research to verify this property. This study aimed to evaluate the antibacterial activity of P. scutellaria Fosberg against bacteria that cause body odor.

Methods: Since body odor is caused by activities of bacteria that live in the armpits, bacteria from human armpit were isolated and identified as Acinetobacter sp. The bacteria have the potential to be pathogenic and resistant to common antibiotics. P. scutellaria was extracted using different solvents, i.e., hexane, ethyl acetate, and methanol. Using these extracts, the antibacterial activity of P. scutellaria against Acinetobacter sp. was tested through well diffusion and colony-forming unit methods.

Results: Hexane and ethyl acetate fractions of P. scutellaria extract showed strong antibacterial activities against Acinetobacter sp., while methanol fraction did not exhibit any antibacterial activity against these bacteria.

Conclusion: P. scutellaria extract has the potential to be used as an antibacterial agent against Acinetobacter sp. on human armpit.

Downloads

Download data is not yet available.

References

Nugraha AS, Keller PA. Revealing indigenous Indonesian traditional medicine: Anti-infective agents. Nat Prod Commun 2011;6:1953-66.

Wulandari L, Retnaningtyas Y, Nuri N, Lukman H. Analysis of flavonoid in medicinal plant extract using infrared spectroscopy and chemometrics. J Anal Methods Chem 2016;2016:1-6.

Dalimartha S. Atlas Tumbuhan Obat Indonesia. Jakarta: Trubus Agriwidya; 1999.

Raina MH. Ensiklopedi Tanaman Obat untuk Kesehatan. Yogyakarta: Absolut; 2011.

Fredrich E, Barzantny H, Brune I, Tauch A. Daily battle against body odor: Towards the activity of the axillary microbiota. Trends Microbiol 2013;21:305-12.

Grice EA, Segre JA. The skin microbiome. Nat Rev Microbiol 2011;9:244-53.

Manchanda V, Sanchaita S, Singh N. Multidrug resistant acinetobacter. J Glob Infect Dis 2010;2:291-304.

Roca I, Espinal P, Vila-FarrÃ©s X, Vila J. The Acinetobacter baumannii oxymoron: Commensal hospital dweller turned pan-drug-resistant menace. Front Microbiol 2012;3:148.

Perez F, Hujer AM, Hujer KM, Decker BK, Rather PN, Bonomo RA, et al. Global challenge of multidrug-resistant Acinetobacter baumannii. Antimicrob Agents Chemother 2007;51:3471-84.

Poulakou G, Bassetti M, Righi E, Dimopoulos G. Current and future treatment options for infections caused by multidrug-resistant gram-negative pathogens. Future Microbiol 2014;9:1053-69.

Irulandi K, Geetha S, Mehalingam P. Antimicrobial activity of selected Indian folk medicinal plants: Myristica fatua, Alstonia boonei, Helicteres isora, Vitex altissima, and Atalantia racemosa. Asian J Pharm Clin Res 2017;10:277-80.

Karim R, Mahmud MN, Hakim MA. Production of bacteriocin like substances as antipathogenic metabolites by Staphylococcus warneri isolated from healthy human skin. Univ J Micr Res 2017;5:40-8.

Sangwan P, Kumar H. Synthesis, characterization, and antibacterial activities of chromium oxide nanoparticles against Klebsiella pneumonia. Asian J Pharm Clin Res 2017;10:206-9.

Davis WW, Stout TR. Disc plate method of microbiological antibiotic assay. I. Factors influencing variability and error. Appl Microbiol 1971;22:659-65.

Chatzispyrou IA, Held NM, Mouchiroud L, Auwerx J, Houtkooper RH. Tetracycline antibiotics impair mitochondrial function and its experimental use confounds research. Cancer Res 2015;75:4446-9.

Sari Y, Wardatun S, Miranti M. Uji toksisitas dan aktivitas antioksidan minuman jelly daun Mangkokan (Nothopanax scutellarium Merr.). Bogor: Universitas Pakuan; 2011.