• NOOR S JAAFAR Department of Pharmacognosy and Medicinal Plants, College of Pharmacy, University of Baghdad, Baghdad, Iraq.
  • IMAN S JAAFAR Department of Pharmaceutics, College of Pharmacy, University of Almustansiriyah, Baghdad, Iraq.



Eruca sativa, Jarjeer, Erucin, Aphrodisiac, Pharmaceutical preparation, Cream, Wax


Eruca sativa (jarjeer) is an annual herb (family Brassicaceae), which contains a wide range of chemicals and minerals with nutraceutical and organoleptic characteristics. Jarjeer was generally used as a food and traditionally mainly consumed due to its aphrodisiac properties. This crop known to contain various phytochemicals such as flavonoids, phenolic acids, terpens, carotenoids, tannins, glycosides, saponins, sterols, alkaloids, and other secondary metabolites. In leaves, kaempferol and its derivatives, glucosativin, are the main flavonoids and glucosinolate, respectively, while erucic acid and glucoerucin are the main fatty acid and glucosinolate, respectively. Medicinally, the plant has antibacterial, antidiabetic, antihypertensive, antiplatelet, and antioxidant activity and stimulates hair growth and other effects. Trails on topical pharmaceutical preparations involve the use of E. sativa which had been done. These preparations include creams and waxs which are intended to be used for potentiating hair growth and skin fungal and bacterial infection.


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Al-Shimmary BA. Study the sub acute effect of Eruca sativa leaves extract on hematological parameters of male rats. Kufa J Vet Sci 2017;8:232-7.

Al-Qudah MM. Effects of Eruca sativa leaves extracts on testes, fertility potential and testosterone concentration in male rats. Ann Res Rev Bio 2017;16:1-7.

El Nagar MM, Mekawi EM. Comparison of different genotypes of rocket (Eruca sativa) in terms of chemical. Middle East J Agric 2014;3:1074-82.

Dolezalova V, Duchoslav M, Dusek K. Biology and yield of rocket (Eruca sativa Mill.) under field conditions of the Czech Republic (Central Europe). Not Bot Horti Agrobo 2013;41:530-7.

Bansal P, Medhe S, Ganesh N, Srivastava MM. Antimelanoma potential of Eruca sativa seed oil and its bioactive principles. Indian J Pharm Sci 2015;77:208-17.

Cavaiuolo M, Ferrante A. Nitrates and glucosinolates as strong determinants of the nutritional quality in rocket leafy salads. Nutrients 2014;6:1519-38.

Khoobchandani M, Ojeswi BK, Ganesh N, Srivastava MM, Gabbanini S, Matera R, et al. Antimicrobial properties and analytical profile of traditional Eruca sativa seed oil: Comparison with various aerial and root plant extracts. Food Chem 2010;120:217-24.

Somos AS, Koukounaras A. Quality and postharvest physiology of rocket leaveshemical. Fresh Produce 2007;1:59-65.

Kishore L, Kaur N, Kajal A, Singh R. Extraction, characterization and evaluation of Eruca sativa against Streptozotocin-induced diabetic nephropathy in rat. Bangladesh J Pharm 2017;12:216-27.

Bouacida S, Koubaier H, Snoussi A, Fauconnier ML, Bouzouita N. Glucosinolate profiles by HPLC-DAD, phenolic compositions and antioxidant activity of Eruca vesicaria longirostris: Impact of plant part and origin. Med J Chem 2016;5:528-39.

Alqasoumi S. Carbon tetrachloride-induced hepatotoxicity: Protective effect of ‘rocket’ Eruca sativa L. in rats. Am J Chin Med 2010;38:75-88.

Ansari MN. Influence of dietary rocket leaves on diuresis and urinary electrolytes excretion in high fat diet-induced obese rats. BEPLS 2015;4:9-13.

El Nagar MM, Mekawi EM. Comparison of different genotypes of rocket (Eruca sativa) in terms of chemical compounds extracted from seeds and in the callus induced from tissue culture. Int J Appl Res Rev 2014;3:1074-82.

Ali A, Bashir U, Haider MS. Bio –control effect of Eruca sativa Mill. oil against the hazardous food borne pathogens. Pak J Pat 2014;26:181-5.

Farooq Z, Iqbal Z, Mushtaq S, Muhammad G, Iqbal MZ, Arshad M, et al. Ethnoveterinary practices for the treatment of parasitic diseases in livestock in cholistan desert (Pakistan). J Ethnopharmacol 2008;118:213-9.

Gugliandolo A, Giacoppo S, Ficicchia M, Aliquò A, Bramanti P, Mazzon E, et al. Eruca sativa seed extract: A novel natural product able to counteract neuroinflammation. Mol Med Rep 2018;17:6235-44.

Shaban N, Abdel-Rahman S, Haggag A, Awad D, Bassiouny A, Talaat I, et al. Combination between taxol-encapsulated liposomes and Eruca sativa seed extract suppresses mammary tumors in female rats induced by 7,12 dimethylbenz(α)anthracene. Asian Pac J Cancer Prev 2016;17:117-23.

Baeshen AA. Use of pseudomonas aeruginosa as fertilizer in Eruca sativa. IJCAMS 2016;5:301-12.

Mahdy SS. The antigenotoxicity of Eruca sativa Mill extract on bone marrow cells of male albino mice treated with vincristine. IHJPAS 2012;25:26-32.

EL Sadek MF. Chemical constituents of Eruca sativa and treatment activity against paracetamol inducing hepatic injury in experimental rats. J Nutr Health 2014;9:73-84.

Marwat SK, Rehman F, Khan AA. Phytochemistry and pharmacological values of rocket (Eruca sativa Miller). Int J Health 2016;6:1-7.

Arora R, Singh B, Vig AP, Arora S. Conventional and modified hydrodistillation method for the extraction of glucosinolate hydrolytic products: A comparative account. Springerplus 2016;5:479.

Bell L, Methven L, Signore A, Concha MJ, Wagstaff. C. Analysis of seven salad rocket (Eruca sativa) accessions: The relationships between sensory attributes and volatile and non-volatile compounds. Food Chem 2017;1:181-91.

Uğur A, Süntar I, Aslan S, Orhan IE, Kartal M, Sekeroğlu N, et al. Variations in fatty acid compositions of the seed oil of Eruca sativa Mill. Caused by different sowing periods and nitrogen forms. Pharmacogn Mag 2010;6:305-8.

Mashi SK. Effect of Eruca sativa leaves extract on liver enzymes and lipid profile in phosphoric acid induced liver damage in male rabbits. J Entomol Zool Stud 2017;5:1011-5.

Kole C. Wild Crop Relatives: Genomic and Breeding Resources: Oilseeds. Berlin Heidelberg: Springer-Verlag; 2011. p. 158.

Garg G, Sharma V. Eruca sativa (L.): Botanical description, crop improvement, and medicinal properties. J Herbs Spices Med Plants 2014;20:171-82.

Gupta SK. Biology and Breeding of Crucifers. London: CRC Press; 2011. p. 46-7.

Jirovetz L, Smith D, Buchbauer G. Aroma compound analysis of Eruca sativa (Brassicaceae) SPME headspace leaf samples using GC, GC−MS. J Agric Food Chem 2002;50:4643-6.

Ahmed DI. Role of Eruca sativa, Negella sativa and bee pollen grains in improving liver, kidney and antioxidant status in rats. Int J Biol Pharm All Sci 2015;4:6604-19.

Gulfrazi M, Sadiqi A, Tariq H, Imran M, Qureshi R, Zeenat A. Phytochemical analysis and antibacterial activity of Eruca sativa seed. Pak J Bot 2011;43:1351-9.

Yadava TP, Friedt DW, Gupta SK. Oil content and fatty acid composition of taramira (Eruca sativa L.) genotypes. J Food Sci Technol 2013;35:557-8.

Tassi EM, Duarte RM, Amaya-Farfan J. Partial nutrient characterization of arugula (rocket - Eruca sativa L.) and the effect of heat treatment on its lipoxidase activity. Brazil J Food Sci Technol 2018;24:1-7.

Tonguc M, Erbas S. Evaluation of fatty acid compositions and some seed characters of common wild plant species of Turkey. Turk J Agric 2012;36:673-9.

Nazif NM, Habib A, Tawfik W, Hassan R. Chemical composition and cytotoxic activity of Eruca sativa L. seeds cultivated in Egypt. Asian J Chem 2010;22:2407-16.

Hetta MH, Owis AI, Haddad PS, Eid HM. The fatty acid-rich fraction of Eruca sativa (rocket salad) leaf extract exerts antidiabetic effects in cultured skeletal muscle, adipocytes and liver cells. Pharm Biol 2017;55:810-8.

Ohta K, Takeshita T, Funabashi M, Oda S. Naturally grown rucola, Eruca sativa, contains more α-linolenic acid than conventionally grown rucola. Plant Biotechnol J 2016;33:277-9.

Nagaraj G. Oilseeds: Properties, Processing, Products and Procedures. India: New India publishing Agency; 2009. p. 36.

El-Fadaly HA, El-Kadi SM, El-Moghazy MM, Soliman AA, El-Haysha MS. Antioxidant activity studies on extracts of Eruca sativa seed meal and oil, detoxification, the role of antioxidants in the resistant microbes. Int J Sci Res Med 2017;6:31-51.

Saqqa GA, Alian A, Ismail F, Ramzy S. Chemical composition of rocket, thyme and parsley essential oils and their effect on some fungi and aflatoxin production. J Toxicol Appl Pharm 2018;4:277-82.

Miyazawa M, Maehara T, Kurose K. Composition of the essential oil from the leaves of Eruca sativa. Flavor Fragr J 2002;17:187-90.

Omri Hichri A, Mosbah H, Majouli K, Besbes Hlila M, Ben Jannet H, Flamini G, et al. Chemical composition and biological activities of Eruca vesicaria Subsp. Longirostris essential oils. Pharm Biol 2016;54:2236-43.

Znidarčič D, Ban D, Sircelj H. Carotenoid and chlorophyll composition of commonly consumed leafy vegetables in Mediterranean countries. Food Chem 2011;129:1164-8.

Villatoro-Pulido M, Priego-Capote F, Álvarez-Sánchez B, Saha S, Philo M, Obregón-Cano S, et al. An approach to the phytochemical profiling of rocket [Eruca sativa (Mill.) thell]. J Sci Food Agric 2013;93:3809-19.

Michael HN, Shafik RE, Rasmy GE. Studies on the chemical constituents of fresh leaf of Eruca sativa extract and its biological activity as anticancer agent in vitro. J Med Plants Res 2011;5:1184-91.

Corleto KA, Singh J, Jayaprakasha GK, Patil BS. Storage stability of dietary nitrate and phenolic compounds in beetroot (Beta vulgaris) and arugula (Eruca sativa) juices. J Food Sci 2018;83:1237-48.

Kim B, Choi YE, Kim HS. Eruca sativa and its flavonoid components, quercetin and isorhamnetin, improve skin barrier function by activation of peroxisome proliferator-activated receptor (PPAR)-α and suppression of inflammatory cytokines. Phytother Res 2014;28:1359-66.

Cartea ME, Francisco M, Soengas P, Velasco P. Phenolic compounds in brassica vegetables. Molecules 2010;16:251-80.

Bell L, Wagstaff C. Glucosinolates, myrosinase hydrolysis products, and flavonols found in rocket (Eruca sativa and Diplotaxis tenuifolia). J Agric Food Chem 2014;62:4481-92.

Abdul-Jalil TZ. Phytochemicals screening by GC/MS and determination of some flavonol in cultivated Iraqi Eruca sativa dried leaves extract and its biological activity as antioxidant. Int J Pharm Pharm Res 2016;8;1722-30.

Sadiq A, Hayat MQ, Mall SM. Qualitative and quantitative determination of secondary metabolites and antioxidant potential of Eruca sativa. Nat Prod Chem Res 2014;2:1-7.

Sajeeth CI, Manna PK, Manavalan R, Jolly C. Quantitative estimation of gallic acid, rutin and quercetin in certain herbal plants by HPTLC method. Der Chem Sin 2010;1:80-5.

Di Gioia F, Avato P, Serio F, Argentieri MP. Glucosinolate profile of Eruca sativa, Diplotaxis tenuifolia and Diplotaxis erucoides grown in soil and soilless systems. J Food Compost Anal 2018;69:197-204.

Chun J, Arasu MV, Lim Y, Kim S. Variation of major glucosinolates in different varieties and lines of rocket salad. Hort. Environ Biotechnol 2013;54:206-13.

Bell L, OrunaConcha MJ, Wagstaff C. Identification and quantification of glucosinolate and flavonol compounds in rocket salad (Eruca sativa, Eruca vesicaria and Diplotaxis tenuifolia) by LCMS: Highlighting the potential for improving nutritional value of rocket crops. Food Chem 2015;172:852-61.

Bennett RN, Rosa EA, Mellon FA, Kroon PA. Ontogenic profiling of glucosinolates, flavonoids, and other secondary metabolites in Eruca sativa (salad rocket), Diplotaxis erucoides (wall rocket), Diplotaxis tenuifolia (wild rocket), and Bunias orientalis (Turkish rocket). J Agric Food Chem 2015;54:4005-15.

Grubben GJ, Denton OA. Plant Resources of Tropical Africa 2 Vegetables. Netherlands: PROTA Foundation, Backhuys Publishers; 2004. p. 295.

Kim S, Ishii G. Glucosinolate profiles in the seeds, leaves and roots of rocket salad (Eruca sativa Mill.) and anti-oxidative activities of intact plant powder and purified 4-methoxyglucobrassicin. J Soil Sci Plant Nutr 2006;52:394-400.

Fechner J, Kaufmann M, Herz C, Eisenschmidt D, Lamy E, Kroh LW, et al. The major glucosinolate hydrolysis product in rocket (Eruca sativa L.), sativin, is 1,3-thiazepane-2-thione: Elucidation of structure, bioactivity, and stability compared to other rocket isothiocyanates. Food Chem 2018;261:57-65.

Bennett RN, Carvalho R, Mellon FA, Eagles J, Rosa EA. Identification and quantification of glucosinolates in sprouts derived from seeds of wild Eruca sativa L. (salad rocket) and Diplotaxis tenuifolia L. (wild rocket) from diverse geographical locations. J Agric Food Chem 2007;55:67-74.

Neugart S, Baldermann S, Hanschen FS, Klopsch R, Wiesner-Reinhold M, Schreiner M. The intrinsic quality of brassicaceous vegetables: How secondary plant metabolites are affected by genetic, environmental, and agronomic factors. Sci Hort 2018;233:460-78.

Barlas NT, Irget ME, Tepecik MM. Mineral content of the rocket plant (Eruca sativa). AJB 2011;10:14080-82.

Guenane H, Gherib A, Bakchiche B, Carbonell-Barrachina AA. Antioxidant capacity, mineral content and essential oil composition from select algerian medicinal plants. St. Cerc. St. CICBIA 2017;18:275-89.

Khan H, Khan MA. Antiulcer effect of extract/Fractions of Eruca sativa: Attenuation of urease activity. J Evid Based Complementary Altern Med 2014;19:176-80.

Thiab A, Hussein S, Hamad MN. Possible gastric protective and therapeutic effect of Eruca sativa laxative extract against ulcer induced by ethanol in rats. Int J Pharm Clin 2016;3:1-6.

Alqasoumi S, Al-Sohaibani M, AlHowiriny T, AlYahya M, Rafatullah S. Rocket “Eruca sativa”: A salad herb with potential gastric antiulcer activity. World J Gastroenterol 2009;15:1958-65.

Kishore L, Kaur N, Singh R. Evaluation of antioxidant activity and total phenolic content of Eruca sativa L. Seeds. Int J Toxicol Pharm Res 2016;8:146-51.

Koubaa M, Driss D, Bouaziz F, Ghorbe RE, Chaabouni SE. Antioxidant and antimicrobial activities of solvent extract obtained from rocket (Eruca sativa L.) flowers. Free Rad Antiox 2015;5:29-34.

Maia ML, Correia-Sá L, Coelho A, Barroso MF, Domingues VF, Delerue-Matos C, et al. Eruca sativa: Benefits as antioxidants source versus risks of already banned pesticides. J Environ Sci Health B 2015;50:338-45.

Barillari J, Canistro D, Paolini M, Ferroni F, Pedulli GF, Iori R, et al. Direct antioxidant activity of purified glucoerucin, the dietary secondary metabolite contained in rocket (Eruca sativa mill.) seeds and sprouts. J Agric Food Chem 2005;53:2475-82.

Rizwana H, Mona S, Alwhibi FK, Soliman DA. Chemical composition and antimicrobial activity of Eruca sativa seeds against pathogenic bacteria and fungi. J Appl Pharm Sci 2016;26:1859-77.

Doulgeraki AI, Efthimiou G, Paramithiotis S, Pappas KM, Typas MA, Nychas GJ, et al. Effect of rocket (Eruca sativa) extract on MRSA growth and proteome: Metabolic adjustments in plant-based media. Front Microbiol 2017;8:782.

Malik SN. Antibacterial activity of olive (Olea europaea) leaves and arugula (Eruca sativa) seeds extract. Int J Pharm Pharm Res 2015;7:307-10.

Razooqi RH, Shkeer HK, Alwan YO, Hayder MI. Effect of Eruca sativa oil on broilers preformance and some blood traits. Int J Sci Nat 2014;4:479-82.

Ansari MN, Ganaie MA. Ameliorative effect of rocket leaves on fertility in streptozotocin-induced diabetic rats. Int Res 2014;3:89-97.

Hadi MA, Almamoori AM, Alaa TS, Hameedi EH. Oxidative response associated with treatment of male albino rats with Eruca sativa Mill leaves extract and correlations with complete blood picture. Int J Pharm Sci Res 2017;9:2278-85.

Hussein ZF. Study the effect of Eruca sativa leaves extract on male fertility in albino mice. J Univ Nat Sci 2013;16:143-6.

Abd El-Aziz GS, El-Fark MO, Hamdy RM. Protective effect of Eruca sativa seed oil against oral nicotine induced testicular damage in rats. Tissue Cell 2016;48:340-8.

Alhowiriny TA, Al-Rehaily AJ, El Tahir KE, Al-Taweel AM, Perveen S. Molecular mechanisms that underlie the sexual stimulant actions of ginger (Zingiber officinale Rosocoe) and garden rocket (Eruca sativa L.). J Med Pharm Res 2013;7:2370-9.

Salem MA, Moustafa NA. Histological and quantitative study of the effect of Eruca sativa seed oil on the testis of albino rat. Egypt J Hosp Med 2001;2:148-62.

Hussein J, Salah A, Oraby F, Nour El-Deen A, El-Khayat Z. Antihepatotoxic effect of Eruca sativa extracts on alcohol induced liver injury in rats. J Med Sci 2010;6:381-9.

Shatta GF. A review article on hyperlipidemia: Types, treatments and new drug targets. BPJ 2014;7:399-409.

Uzun M, Kaya A. Ethnobotanical research of medicinal plants in Mihalgazi (Eskişehir, Turkey). Pharm Biol 2016;54:2922-32.

El-Gengaihi SE, Salem A, Bashandi SA, Ibrahim NA, Abd el-Hamid SR. Hypolipidemic effect of some vegetable oils in rats’ food. Agric Environ 2004;2:88-93.

Seham SK, Magda SM, Madiha MA. Effect of some plant oils and garlic on lipids of rats fed on high cholesterol diet. Int Food Res J 2015;22:1307-14.

Shah AJ, Salma U, Khan T, Khan S, Qayyum R, Qamar H. Antihypertensive effects and potential vascular mechanisms of the extract and fractions of Eruca sativa and euricin. Clin Exp Pharmacol 2016;6:59-65.

Amjad MS. Ethnobotanical profiling and floristic diversity of Bana valley, Kotli (Azad Jammu and Kashmir). Pak Appl Pharm J Pharm Tech 2015;5:292-9.

Ali-Shtayeh MS, Jamous RM, Jamous RM, Salameh NM. Complementary and alternative medicine (CAM) use among hypertensive patients in Palestine. Complement Ther Clin Pract 2013;19:256-63.

Salma U, Khan T, Shah AJ. Antihypertensive effect of the methanolic extract from Eruca sativa Mill. (Brassicaceae) in rats: Muscarinic receptor-linked vasorelaxant and cardiotonic effects. J Ethnopharmacol 2018;224:409-20.

Melchini A, Traka MH. Biological profile of erucin: A new promising anticancer agent from cruciferous vegetables. Toxins (Basel) 2010;2:593-612.

Peter SJ, Sabina EP. Global current trends in natural product for diabetes managements Int J Pharm Pharm Scii 2016;8:21-8.

Hetta MH, Aly HF, Arafa A. Inhibitory effect of Eruca sativa Mill. On carbohydrate metabolizing enzymes. Int J Pharm Sci Rev Res 2014;26:205-8.

Ahmed OM, Abdel-Reheim ES, Ashour MB, Fahim HI, Mohamed HH. Efficacies of Eruca sativa and Raphanus sativus seeds’ oils in streptozotocin induced diabetic rats. Int J Clin Endocrinol Metab 2016;2:34-43.

El-Missiry MA, El Gindy AM. Amelioration of alloxan induced diabetes mellitus and oxidative stress in rats by oil of Eruca sativa seeds. Ann Nutr Metab 2000;44:97-100.

Ansari MN. Ameliorative effect of Eruca sativa extracts on glucose and urinary volume in streptozoticine - induced diabetic rats. Int J Biol Pharm All Sci 2014;3:1092-100.

Rani I, Akhund S, Suhail V, Abro H. Antimicrobial potential of seed extract of Eruca sativa. Pak J Bot 2010;42:2949-53.

Abodola MA, Lutfi MF, Bakhiet AO, Mohamed AH. The anti-edema effect of Eruca sativa seeds. Science 2015;5:1340-4.

Elgazar AF, AboRaya AO. Nephroprotective and diuretic effect of three medicinal herbs against gentamicin-induced nephrotoxicity in male rats. PJN 2013;12:715-22.

Shalaby MA, Hammouda AA. Nephroprotective diuretic and antioxidant effects of some medicinal herbs in gentamicin-nephrotoxic rats. J Intercult Ethnopharmacol 2014;3:1-8.

Sarwar Alam M, Kaur G, Jabbar Z, Javed K, Athar M. Eruca sativa seeds possess antioxidant activity and exert a protective effect on mercuric chloride induced renal toxicity. Food Chem Toxicol 2007;45:910-20.

Hussein UA. Role of Eruca sativa in prevention of induced nephrocalcinosis in rabbits. Kerbala J Pharm Sci 2018;14:65-73.

Aggarwal D, Sharma M, Singla SK. The role of natural antioxidants as potential therapeutic agent in nephrolithiasis. Asian J Pharm Clin Res 2013;6:48-53.

Alarcón M, Fuentes M, Carrasco G, Palomo I. A novel role of Eruca sativa mill. (Rocket) extract: Antiplatelet (NF-κB Inhibition) and antithrombotic activities. Nutrients 2014;6:5839-52.

Ramzan I, Phytotherapies: Efficacy, Safety, and Regulation United State of America. New Jersey: John Wiley and Sons, Inc. Hoboken; 2015. p. 172.

Dris R, Jain SM, Khan IA. Environment and Crop Production. New York: CRC Press; 2002. p. 68.

Abbasi AM, Khan SM, Ahmad M, Khan MA, Quave CL, Andrea A. Botanical ethnoveterinary therapies in three districts of the lesser Himalayas of Pakistan. Ethnobiol Ethnomed 2013;9:1-20.

Shatalebi MA, Safaeian L, Baradaran A, Alamdarian M. Preparation and evaluation of a hair wax containing propolis and Eruca sativa seed oil for hair growth. Adv Biomed Res 2016;28:182.

Sanad RA, Mabrouk MI. Development and assessment of stable formulations containing two herbal antimicrobials: Allium sativum L. and Eruca sativa miller seed oils. Drug Dev Ind Pharm 2016;42:958-68.

Taha KF, Elhawary SS, Elefnawy HM, Mabrouk MI, Sanad RA, Elharriry MY. Formulation and assessment of herbal hair cream against dermatophytes. Int J Pharm Pharm Sci 2016;8:167-73.



How to Cite

S JAAFAR, N., and I. S JAAFAR. “ERUCA SATIVA LINN.: PHARMACOGNOSTICAL AND PHARMACOLOGICAL PROPERTIES AND PHARMACEUTICAL PREPARATIONS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 12, no. 3, Mar. 2019, pp. 39-45, doi:10.22159/ajpcr.2019.v12i3.30893.



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