SYNTHESIS OF SOME NOVEL PYRAZOLE DERIVATIVES AND EVALUATION OF THEIR PURIFICATION OF CHROMATOGRAPHY IN THIN-LAYER CHROMATOGRAPHY

Swapna B; Vijey Aanandhi M

doi:10.22159/ajpcr.2018.v11s4.31678

Authors

Swapna B Department of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Chennai, Tamil Nadu, India.
Vijey Aanandhi M Department of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.22159/ajpcr.2018.v11s4.31678

Keywords:

MP, Solubility, Rf values, Spectral studies

Abstract

Objective: The main objective of the study is to synthesis some novel pyrimidine scaffold which has wide range of properties of biological activities.

Methods: Synthesis of different pyrazole derivatives compounds identification and characterization (M.P, solubility, Rf values, and spectral studies). The present work was characterized by infrared, nuclear magnetic resonance, and mass spectral analysis pharmacological evaluation.

Results: Identification and characterization (M.P, solubility, Rf values and spectral studies) are carried out.

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