Vitex trifolia: AN ETHNOBOTANICAL AND PHARMACOLOGICAL REVIEW

Suchitra M; BINOY  VARGHESE CHERIYAN

doi:10.22159/ajpcr.2018.v11s4.31689

Authors

Suchitra M Department of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai, Tamil Nadu, India.
BINOY VARGHESE CHERIYAN

DOI:

https://doi.org/10.22159/ajpcr.2018.v11s4.31689

Keywords:

Larvicidal, Analgesic, Anti-inflammatory, Antimicrobial, Antioxidant, Hepatoprotective, Antihistamine and antiasthmatic, Wound healing, Vitex trifolia

Abstract

Objective: The perspective of this review is the list of activities carried out or studied along with description, habitat macro-microscopy, phytoconstituents, medicinal uses, clinical studies, and toxicology on the plant Vitex trifolia.

Methods: A large number of the species of the Genus Vitex are widely employed in Indian traditional systems of medicine. A total of 270 plant species of genus Vitex have been identified worldwide. V. trifolia is used in Ayurveda and Unani. These species are rich source of secondary metabolites such as polyphenolic compounds, terpenoids, phytosterols, protein and amino acids, tannins, and saponins.

Results: The results of various studies V. trifolia possess larvicidal, analgesic, anti-inflammatory, antimicrobial, antioxidant, hepatoprotective, antihistaminic, and antiasthmatic properties.

Conclusion: The review on V. trifolia explains that there is a need for detailed study on its clinical relevance and safety of plant extracts.

Downloads

Download data is not yet available.

References

Kumar S, Saini M, Kumar V, Prakash O, Arya R, Rana M, et al. Traditional medicinal plants curing diabetes a promise for today and

tomorrow. Asian J Tradit Med 2012;7:3173-84.

Kumar MA, Niranjan U, Rao M, Padhi MM, Babu R. A review of the important chemical constituents and medicinal uses of Vitex genus.

Asian J Tradit Med 2011;6:54-60.

Jose BE, Jebaseelan S, Meera R. Phytochemical investigation and anti-cancer activity of Vitex trifolia. J Pharm Sci Res 2017;9:1056-62.

Thenmozhi S, Sundaram RS, Kumar JP, Bihari CG. Pharmacognostical and phytochemical investigation on leaves of Vitex trifolia Linn. J Pharm Res 2011;4:1259-62.

Van der Valk JM, Christiene L, Mark N. Macroscopic authentication of Chinese materia medica (CMM): A UK market study of seeds and

fruits. J Herb Med 2017;8:40-51.

Meena A, Singh U, Yadav A, Singh B, Rao M. Pharmacological and phytochemical evidences for the extracts from plants of the genus Vitex-a review. Int J Pharm Clin Res 2010;2:1-9.

Cousins MM, Briggs J, Chuck G, Whitwell T, Whetstone J. Beach Vitex (Vitex rotundifolia) an invasive coastal species. Weed Sci Soc Am

;6:101-3.

Zeng X, Fang Z, Wu Y, Zhang H. Chemical constituents of the fruits of Vitex trifolia L. Zhongguo Zhong Yao Za Zhi 1996;21:167-8, 191.

Ono M, Sawamura H, Ito Y, Mizuki K, Nohara T. Diterpenoids from the fruits of Vitex trifolia. Phytochemistry 2000;55:873-7.

HernÃ¡ndez MM, Heraso C, Villarreal ML, Vargas-Arispuro I, Aranda E. Biological activities of crude plant extracts from Vitex trifolia L.

(Verbenaceae). J Ethnopharmacol 1999;67:37-44.

Kannathasan K, Senthilkumar A, Venkatesalu V. Mosquito larvicidal activity of methyl-p-hydroxybenzoate isolated from the leaves of Vitex trifolia Linn. Acta Trop 2011;120:115-8.

Li WX, Cui CB, Cai B, Wang HY, Yao XS. Flavonoids from Vitex trifolia L. Inhibit cell cycle progression at G2/M phase and induce

apoptosis in mammalian cancer cells. J Asian Nat Prod Res 2005;7:615-26.

Arifin B, Nasution R, Saidi N, Marianne, Aprilia S. Vitex trifolia plant control of mice environmentally friendly. Int J Chem Tech Res

;6:4595-600.

Chan EW. Medicinal plants of sandy shores a short review on V trifolia L. and Iomoea pes caprae. Indian J Nat Prod Resour 2016;7:107-15.

Roqaiya M, Begum W, Majeedi SF. A review on unani traditional uses of sambhalu in females as well as phytochemical and pharmacological

properties. Int J Pharm Sci Res 2017;7:31-41.

Mustariche R, Windhu WY, Ryan W. Anti-inflammation tablet of legundi (Vitex triolia) ethanol extract with variation of sodium starch glycolate. Int J Res Ayurveda Pharm 2016;7:114-7.

Ahmad FB, Holdsworth DK. Traditional medicinal plants of Sabah state Malaysia the rungus people of Kudat. Int J Pharmacogn 1995;33:262-4.

Bajpai A, Ojha JK, Sant HR. Medicobotany of the Varanisi district Uttar Pradesh. Int J Pharmacogn 1995;33:172-6.

Aranda E, Hernandez MM, Heraso C, Villarreal ML, Arispuro IV. Biological activities of crude plant extracts from Vitex trifolia L. J Ethnopharmacol 1999;67:37-44.

Kannathasan K, Senthilkumar A, Chandrasekaran M, Venkatesalu V. Differential larvicidal efficacy of four species of Vitex against Culex quinquefasciatus larvae. Parasitol Res 2007;101:1721-3.

Yasuyuki IT, Noharab T. Four new halimane-type diterpenes, vitetrifolins D-G, from the fruit of Vitex trifolia. Chem Pharm Bull 2001;49:1220-2.

Apichart S, Kittipong W, Joseph J. Variation of essential oil constituents in Vitex trifolia species. Flavour Fragr J 1991;6:97-9.

Geetha V, Doss A, Doss AP. Antimicrobial potential of Vitex trifolia Linn. Anc Sci Life 2004;23:30-2.

Ahmed MR, Anis M. Role of TDZ in the quick regeneration of multiple shoots from nodal explant of Vitex trifolia L.--an important medicinal plant. Appl Biochem Biotechnol 2012;168:957-66.

Deivam S, Anbu J, Ravichandran V, Senthilkumar KL. Antioxidant and anti-tumor activity of poly herbal extract on Ehrlich ascites carcinoma in mice. Int J Biol Pharm Res 2013;4:1103-7.

Goverdhan P, Diwakar B. Anti-nociceptive and anti-inflammatory effects of the leaf extract of Vitex trifolia Linn. In experimental animals. Ethnobot Leaf 2009;13:65-72.

Kulkarni LA. Analgesic potential of Vitex trifolia Linn (Verbaneacae). Asian J Pharm Clin Res 2014;7:157-9.

Pfuzia A, Devi RB, Sharatchandra K, Debashree BN, Banylla SN, Sania KH, et al. Studies on the anti-inflammatory effect of the aqueous. Int J Pharm Bio Sci 2013;4:588-93.

Anandan R, Jayakar B, Karar B, Babuji S, Manavalan R, Kumar RS, et al. Effect of ethanol extract of flowers of Vitex trifolia Linn. On CCL4 induced hepatic injury in rats. Pak J Pharm Sci 2009;22:391-4.

Mohammed I, Garbi E, Osman EE, Kabbashi AS, Saleh MS, Mahmoud SA, et al. Cytotoxicity of Vitex trifolia leaf extracts on MCF-7 and vero cell lines. J Sci Innov Res 2015;4:89-93.

Wahyuono S, Alam G, Ikawati Z, Timmerman H, Maeyama K. Antiasthmatic compounds isolated from antiasthmatic JAMUâ€ ingredient legundi leaves (Vitex trifolia L.). Sci Pharm 2009;77:192-3.

Mamjunatha B, Vidya S. Comparative evaluation of wound healing potency of Vitex trifolia L. and Vitex altissima L. Phytother Res 2007;21:457-61.

Natheer SE, Sekar C, Amutharaj P, Rahman MS, Khan KF. Evaluation of antibacterial activity of Morinda citrifolia, Vitex trifolia and Chromolaena odorata. Afr J Pharm Pharmacol 2012;6:783-8.

Tiwari N, Thakur J, Saikia D, Gupta MM. Antitubercular diterpenoids from Vitex trifolia. Phytomedicine 2013;20:605-10.

Hossain MM, Paul N, Sohrab MH, Rahman E, Rashid MA. Antibacterial activity of Vitex trifolia. Fitoterapia 2001;72:695-7.