Effects EFFECTS OF PUMPKIN (CUCURBITA MOSCHATA DURCH) SEED POWDER ON BLOOD GLUCOSE LEVEL IN STREPTOZOTOCIN-INDUCED MICE
DOI:
https://doi.org/10.22159/ajpcr.2019.v12i18.33730Keywords:
Diabetes mellitus, Streptozotocin, Pumpkin, Powder, Seed, MiceAbstract
Objective: The aim of this research is to evaluate the antidiabetic effect of pumpkin seed powder in streptozotocin (STZ)-induced diabetic mice.
Methods: Pumpkin seed was used in seed powder suspension form and then evaluate the phytochemical screening and induced diabetic mice using STZ.
Results: The phytochemical screening showed that pumpkin seed powder has various of phytochemical compounds. The pumpkin seed powder (dose level 100, 150, and 200 mg/kg bw) showed a significant reduction of blood glucose.
Conclusions: Pumpkin seed powder significantly decreases blood glucose level in STZ-induced mice.
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