AN AN OBSERVATIONAL STUDY OF PRESCRIPTION PATTERN OF DRUGS FOR OSTEOARTHRITIS IN A NORTH INDIAN MEDICAL COLLEGE

ASHWANI UMMAT; RANJODH JEET SINGH; SONIA KOCHHAR

doi:10.22159/ajpcr.2019.v12i7.33882

Authors

ASHWANI UMMAT Department of Orthopedics, Maharishi Markandeshwar Institute of Medical Sciences and Research, Maharishi Markandeshwar Deemed to be University, Ambala, Haryana, India.
RANJODH JEET SINGH Department of Pharmacology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Maharishi Markandeshwar Deemed to be University, Ambala, Haryana, India.
SONIA KOCHHAR Department of Physiology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Maharishi Markandeshwar Deemed to be University, Ambala, Haryana, India.

DOI:

https://doi.org/10.22159/ajpcr.2019.v12i7.33882

Keywords:

Osteoarthritis,, Prescription pattern,, Paracetamol,, Acetaminophen, Abbreviations: OA:, osteoarthritis,, NSAIDs: Non-steroidal anti-inflammatory drugs,, DDS: drug delivery system

Abstract

Objective: The objective of the study is to analyze the prescription pattern of drugs for osteoarthritis (OA) in a north Indian medical college collaborated with a tertiary care hospital.

Methods: An observational study was conducted on 300 patients diagnosed with OA in the department of orthopedics in collaboration with the department of pharmacology, and thus, prescription was collected as in a cross-sectional manner for 6 months and the same were analyzed in the Department of Orthopedics in tertiary care hospital collaborated with medical college.

Results: The average age of patients participating in this present study was 56.46±7.4 years with affected age group of 46-60 years. 60 % of females were affected by osteoarthritis outnumbering male (40 %) patients in this present study. The most commonly involved joint was knee joint (87.33 %) in patients diagnosed with osteoarthritis followed by back (6.67 %) and hip joint (6%). The combination therapy (90 %) outweighed monotherapy (10 %) with preferred route of drug administration as oral route (90 %) followed by topical route (10 %). The average number of drugs prescribed for patients of osteoarthritis was 2.62±0.76. This present study concludes that NSAIDs (45.8%) were prescribed most commonly. However, the drug paracetamol was lesser prescribed and other drugs such as Diclofenac (27.22 %) and acetaminophen (34.44 %) most of all followed by Nimesulide (16.67 %), ibuprofen (13.33 %) and Rofecoxib/valdecoxib (8.33 %) were prescribed.

Conclusion: This present study concludes that NSAIDs were most commonly prescribed as p-drugs while paracetamol was undermined prescribed.

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Author Biography

ASHWANI UMMAT, Department of Orthopedics, Maharishi Markandeshwar Institute of Medical Sciences and Research, Maharishi Markandeshwar Deemed to be University, Ambala, Haryana, India.

assistant professor, department of pharmacology.

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