A PRESCRIPTION AUDIT AND ASSESSMENT OF DRUG UTILIZATION PATTERN IN A TERTIARY CARE TEACHING AND REFERRAL HOSPITAL IN UTTAR PRADESH, INDIA

Authors

  • SURABHI ARORA Department of Pharmacology, Era’s Lucknow Medical College and Hospital, Lucknow, Uttar Pradesh, India.
  • AFROZ ABIDI Department of Pharmacology, Era’s Lucknow Medical College and Hospital, Lucknow, Uttar Pradesh, India.
  • DILSHAD ALI RIZVI Department of Pharmacology, Era’s Lucknow Medical College and Hospital, Lucknow, Uttar Pradesh, India.

DOI:

https://doi.org/10.22159/ajpcr.2019.v12i12.35401

Keywords:

Prescription auditing, Drug utilization pattern, Rational prescription, Polypharmacy

Abstract

Objective: The objective of our study is to assess the prescription and drug utilization pattern in a tertiary care teaching and referral hospital in Uttar Pradesh, to investigate the rational use of drugs.

Methods: The study was carried out in the general medicine outpatient department (OPD) setting for a period of 3 months in our tertiary care teaching and referral hospital. The prescriptions were randomly sampled and the photocopies of all the prescriptions were obtained from the OPD during the period of the study and were processed and analyzed for the demographic profile, drug profile, fixed-dose combinations, therapeutic classes of antibiotic prescribed, morbidity profile according to the disease pattern, and prescription pattern including the errors in prescription and the assessment of polypharmacy.

Results: A total of 350 prescriptions were randomly sampled, out of which 312 prescriptions were fit to be analyzed. The total number of drugs in 312 prescriptions was 1022. Basic information of patient was written in 79.25% prescriptions, 84.25% prescriptions were legible, and only 71.21% prescriptions were complete. The majority of prescriptions had at least five drugs ordered which constituted around 43.14% of total number of prescriptions leading to polypharmacy.

Conclusions: Our study highlights that there is a scope for improvement in prescribing patterns in areas of writing legible and complete prescriptions. To lay down the principles of rational pharmacotherapeutics, proper training of the prescribers on rational prescription writing is the need of an hour for improving the quality of prescriptions.

Downloads

Download data is not yet available.

Author Biography

SURABHI ARORA, Department of Pharmacology, Era’s Lucknow Medical College and Hospital, Lucknow, Uttar Pradesh, India.

Associate Professor, PHARMACOLOGY, Era's Lucknow Medical College, Lucknow, U.P

References

Sisay M, Mengistu G, Molla B, Amare F, Gabriel T. Evaluation of rational drug use based on World Health Organization core drug use indicators in selected public hospitals of Eastern Ethiopia: A cross sectional study. BMC Health Serv Res 2017;17:161.

Fijn R, Van den Bemt PM, Chow M, De Blaey CJ, De Jong-Van den Berg LT, Brouwers JR. Hospital prescribing errors: Epidemiological assessment of predictors. Br J Clin Pharmacol 2002;53:326-31.

Singh R. Prescription audit and assessment of drug use pattern using World Health Organization prescribing indicators in a tertiary care teaching and referral hospital in Himachal Pradesh, India. J Med Sci Clin Res 2018;6:377-84.

Himmel W, Lönker B, Kochen MM. Nonformulary drug requests at an academic hospital in Germany-the role of general practitioners’ long-term medication. Eur J Clin Pharmacol 1998;54:41-6.

Abidi A, Gupta S, Kansal S, Ramgopal R. Prescription auditing and drug utilization pattern in a tertiary care teaching hospital of Western UP. Int J Basic Clin Pharmacol 2012;1:184.

Dyasanoor S. Insight into quality of prescription writing-an instituitional study. J Clin Diagn Res 2016;4:564-70.

Devi DP, George J. Diabetic nephropathy: Prescription trends in tertiary care. Indian J Pharm Sci 2008;70:374.

Prinja S, Tripathy J, Bahuguna P. Drug prescription behavior: A cross-sectional study in public health facilities in two states of North India. Perspect Clin Res 2018;9:76.

Ahsan M, Shaifali I, Mallick AK, Singh HK, Verma S, Shekhar A. Prescription auditing based on World Health Organization (WHO) prescribing indicators in a teaching hospital in North India. Int J Res Med Sci 2016;4:1847-52.

Velo GP, Minuz P. Medication errors: Prescribing faults and prescription errors. Br J Clin Pharmacol 2009;67:624-8.

Reason J. Human error: Models and management. BMJ 2000;320:768-70.

Montesi G, Lechi A. Prevention of medication errors: Detection and audit. Br J Clin Pharmacol 2009;67:651-5.

Senthilselvi R, Boopana M, Sathyan L, Visuvasam P, Ganesan V. Drug utilization pattern in paediatric patient in a secondary care hospital. Int J Pharm Pharm Sci 2019;22:69-74.

Seden K, Kirkham JJ, Kennedy T, Lloyd M, James S, Mcmanus A, et al. Cross sectional study of prescribing errors in patients admitted to nine hospitals across North West England. BMJ 2013;3:321-30.

Hazra A, Tripathi SK, Alam MS. Prescribing and dispensing activities at the health facilities of a non-governmental organization. Natl Med J India 2000;13:177-82.

Hutin YJ. Use of injections in healthcare settings worldwide, 2000: Literature review and regional estimates. BMJ 2003;327:1075.

Gupta N, Gupta, D, Sharma, Garg SK, Bhargava VK. Auditing of prescriptions to study utilization of antimicrobials in a tertiary hospital. Indian J Pharmacol 1997;29:411-5.

Chakrabarti A. Prescription of fixed dose combination drugs for diarrhoea. Indian J Med Ethics 2007;4:174-83.

Balaji R, Sekkizhar M, Kumar MA, Nirmala P. An observational study of drug utilization pattern and pharmacovigilance of antipsychotics. Int J Curr Pharm Res 2017;9:56.

Siddarama R, Naidu JB, Joshisree KP, Lakshmi VS. Polypharmacy induced drug interactions, adverse drug reactions (ADR) and medication errors in tertiary care South Indian hospital. Int J Pharm Pharm Sci 2019;5:88-93.

Published

07-12-2019

How to Cite

SURABHI ARORA, AFROZ ABIDI, and DILSHAD ALI RIZVI. “A PRESCRIPTION AUDIT AND ASSESSMENT OF DRUG UTILIZATION PATTERN IN A TERTIARY CARE TEACHING AND REFERRAL HOSPITAL IN UTTAR PRADESH, INDIA”. Asian Journal of Pharmaceutical and Clinical Research, vol. 12, no. 12, Dec. 2019, pp. 161-5, doi:10.22159/ajpcr.2019.v12i12.35401.

Issue

Section

Original Article(s)