• PRAVALIKA M Department of Pharmaceutical Analysis, Geethanjali College of Pharmacy, Hyderabad, Telangana, India.
  • SRIVANI V Department of Pharmaceutical Analysis, Geethanjali College of Pharmacy, Hyderabad, Telangana, India.
  • SAGAR PAMU Department of Pharmacy Practice, Guru Nanak Institutions Technical Campus - School of Pharmacy, Ibrahimpatnam, Ranga Reddy, Hyderabad, Telangana, India.



Alendronate, Respiratory distress, Dyspnoea, Wheezing, Allergic bronchopulmonary aspergillosis, Basophilia, Elevated immunoglobulin E


Respiratory distress is a rare adverse effect of alendronate that is typically associated with severe dyspnoea and wheezing and typically requires hospitalization. The patient with a history of dyspnoea and wheezing during the strenuous workload was treated promptly with alendronate for newly diagnosed osteoporosis. After 2 days, respiratory distress complications were restarted and we accurately reported the patient with basophilia, elevated immunoglobulin E (with a blood test), and allergic bronchopulmonary aspergillosis (with computed tomography scan image). The prospective patient was adequately understood as alendronate-induced respiratory distress with an unfortunate rechallenge method. Although there is no direct causal relationship from this adverse case report, the possible mechanism has discussed typically based on peer-reviewed literature.


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How to Cite

M, P., S. V, and S. PAMU. “ALENDRONATE-INDUCED RESPIRATORY DISTRESS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 13, no. 7, July 2020, pp. 1-2, doi:10.22159/ajpcr.2020.v13i7.37811.



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