INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION BY AN EXTRACT OF OCIMUM BASILICUM SEEDS: AN IN-VITRO STUDY
DOI:
https://doi.org/10.22159/ajpcr.2020.v13i9.37926Keywords:
Ocimum basilicum, Urolithiasis, Calcium oxalate crystallization, NucleationAbstract
Objective: Ocimum basilicum (OB) has been used to treat diverse illnesses which include urinary stone disorder for a reason that historical time in India. We investigated OB seeds for antiurolithic activity.
Methods: Calcium oxalate crystallization becomes triggered by the addition of 0.01 M sodium oxalate answers in normal human urine and nucleation was done.
Results: OB seeds were discovered to be robust and promising antiurolithiatic agents which are in accordance with its use in traditional medication.
Conclusion: An extract of the traditional herb OB has super inhibitory activity on crystalluria and therefore might be useful in dissolving urinary stone; however, in addition, a study in animal fashions of urolithiasis is needed to assess its capability antiurolithiatic interest.
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