COAGULATION PROFILE IN PATIENTS SUFFERING FROM ACUTE BRUCELLOSIS
Abstract
Objective: Although brucellosis has almost been eradicated from most of the developed countries, it still continues to be a major but somehow neglected disease in the developing and underdeveloped countries. In the past, hematological abnormalities like anemia, thrombocytopenia have been reported to be seen in brucellosis patients. The objective of the present study is to observe and study the coagulation profile of patients suffering from acute brucellosis.
Methods: Blood samples were collected from brucellosis patients and healthy volunteers and were analyzed in automated blood coagulation analyzer and automated hematology analyzer to find out the values of prothrombin time (PT), activated partial thromboplastin time (aPTT) and platelet count.
Results: Statistical analysis revealed that there was marginal increase in the aPTT level and platelet count in brucellosis patients than that of the control patients.
Conclusion: The study revealed that there might be a tendency of prolonged aPTT and increase in platelet levels in brucellosis patients.
Keywords: Brucellosis, coagulation profile, prothrombin time (PT), activated partial thromboplastin time (aPTT), platelet count.
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