PERCEPTION OF QUALIFIED MEDICAL PRACTITIONERS TOWARD PRESCRIBING IN INTERNATIONAL NON-PROPRIETARY (GENERIC) NAMES – AN OBSERVATIONAL, CROSS-SECTIONAL STUDY AT A TERTIARY CARE HOSPITAL IN INDIA

MANAB NANDY; KUSHAL BANERJEE; INDRANIL BISWAS; KAJORI NANDY; SOUVIK MAJUMDER; AYAN MUKHERJEE; ALAK KUMAR DAS

doi:10.22159/ajpcr.2021.v14i2.39867

Authors

MANAB NANDY Department of Pharmacology, Medical College, Kolkata, West Bengal, India.
KUSHAL BANERJEE Department of Pharmacology, Medical College, Kolkata, West Bengal, India.
INDRANIL BISWAS Department of ???, Medical College, Kolkata, West Bengal, India,
KAJORI NANDY Department of Paediatrics, PGIMER, Chandigarh, India.
SOUVIK MAJUMDER Department of Pharmacology, Medical College, Kolkata, West Bengal, India.
AYAN MUKHERJEE Department of Pharmacology, Medical College, Kolkata, West Bengal, India.
ALAK KUMAR DAS Department of Pharmacology, Medical College, Kolkata, West Bengal, India.

DOI:

https://doi.org/10.22159/ajpcr.2021.v14i2.39867

Keywords:

Generic name, Perception of qualified medical practitioners, Observational, Cross-sectional Study

Abstract

Objectives: The study was conducted to assess the perception and practice of medical practitioners, working in tertiary care, and teaching institutions in Eastern India, regarding the use of generic (non-proprietary) names while prescribing. The study tried to assess their perception toward using drugs from the National List of Essential Medicine (NLEM), as well.

Methods: An observational, cross-sectional study was conducted. Medical practitioners attached to the institution were considered for the study and those who gave voluntarily consent were included. Hundred participants were interviewed based on convenient random sampling. They were provided with the study questionnaire and the responses were analyzed using Microsoft Excel 2007 using charts and tables.

Results: Majority (43/100) did not feel that generic medicines are as effective as reputed brands, while 32 felt they are of equally effective. About 45% (45/99) felt generics to be equally safe as and 24% (24/99) did not feel so. About 86% considered generics to be cheaper. About 56% did not prefer to substitute with generics in all conditions. About 73% had doubts regarding the quality of production of generics. The decision to use generics was mostly influenced by the lower cost (73%) and by administrative pressure (53%). About 58% felt that the NLEM does not contain all the medicines they would require in practice. About 94% agreed to prescribe more in generics if the quality may be ensured.

Conclusion: Awareness of the NLEM and about generics needs to be improved. Authorities need to ensure the quality of generics and assure the prescribers about it.

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References

Tripathi KD. Essentials of Medical Pharmacology. 8th ed. New Delhi: Jaypee Brothers Medical Publishers; 2019. p. 1064.

WHO. Guidance on INN. WHO. World Health Organization. Available from: https://www.who.int/medicines/services/inn/innquidance/en. [Last accessed on 2020 Jun 07].

Available from: http://www.ipgmer.gov. in/ Pharmacovigilance Committee/MCI_CircularUseofGenericNames20170421.pdf. [Last accessed on 2020 Jun 07].

Roy V, Rana P. Prescribing generics: All in a name. Indian J Med Res 2018;147:442-4.

Kamath A. Prescribing generic drugs using a generic name: Are we teaching it right? Indian J Med Ethics 2016;1:194.

Thakre R, Patil P. Generic drugs: A call for balanced approach. Indian Pediatr 2017;54:692.

Chua GN, Hassali MA, Shafie AA, Awaisu A. A survey exploring knowledge and perceptions of general practitioners towards the use of generic medicines in the Northern state of Malaysia. Health Policy 2010;95:229-35.

Dunne SS, Shannon B, Cullen W, Dunne CP. Beliefs, perceptions and behaviours of GPs towards generic medicines. Fam Pract 2014;31:467-74.

Riner B, Bussy A, Hélène-Pelage J, Moueza N, Lamy S, Carrère P. No generics, doctor? The perspective of general practitioners in two French regions. BMC Health Serv Res 2017;17:707.

Paraponaris A, Verger P, Desquins B, Villani P, Bouvenot G, Rochaix L, et al. Delivering generics without regulatory incentives?: Empirical evidence from French general practitioners about willingness to prescribe international non-proprietary names. Health Policy 2004;70:23-32.

Lewek P, Smigielski J, Kardas P. Factors affecting the opinions of family physicians regarding generic drugs-a questionnaire based study. Bosn J Basic Med Sci 2015;15:45.

Hassali MA, Kong DC, Stewart K. Generic medicines: Perceptions of general practitioners in Melbourne, Australia. J Generic Med 2006;3:214-25.

Spiegel W, Mlczoch-Czerny MT, Jens R, Dowrick C. Quality circles for pharmacotherapy to modify general practitioners’ prescribing behaviour for generic drugs. J Eval Clin Pract 2012;18:828-34.

Fadare JO, Adeoti AO, Desalu OO, Enwere OO, Makusidi AM, Ogunleye O, et al. The prescribing of generic medicines in Nigeria: Knowledge, perceptions and attitudes of physicians. Expert Rev Pharmacoecon Outcomes Res 2016;16:639-50.

O’Leary A, Usher C, Lynch M, Hall M, Hemeryk L, Spillane S, et al. Generic medicines and generic substitution: Contrasting perspectives of stakeholders in Ireland. BMC Res Notes 2015;8:790.

Čatić T, Avdagić L, Martinović I. Knowledge and attitudes of physicians and pharmacists towards the use of generic medicines in Bosnia and Herzegovina. Med Glas 2017;14:25-32.

Labiris G, Fanariotis M, Kastanioti C, Alexias G, Protopapas A, Karampitsakos T, et al. Greek physicians’ perceptions on generic drugs in the era of austerity. Scientifica 2015;2015:251792.

El-Dahiyat F, Kayyali R, Bidgood P. Physicians’ perception of generic and electronic prescribing: A descriptive study from Jordan. J Pharm Policy Pract 2014;7:7.

Shrank WH, Liberman JN, Fischer MA, Girdish C, Brennan TA, Choudhry NK. Physician perceptions about generic drugs. Ann Pharmacother 2011;45:31-8.

Kristina SA, Salsabila NN. Medical doctors’ attitude toward generic substitution in prescribing practice: A survey from Yogyakarta. Int Med J 1994;25:2257-63.

Patel A, Gauld R, Norris P, Rades T. Quality of generic medicines in South Africa: Perceptions versus reality-a qualitative study. BMC Health Serv Res 2012;12:297.

Gupta SK, Nayak RP, Vidyarthi SK. A study on the knowledge, attitude, and practice of generic medicines among the doctors in a tertiary care teaching hospital in South India. Natl J Physiol Pharm Pharmacol 2015;5:39.

Tandel K, Patel N, Zaiwala S, Chavda N, Dhanani J. A study of knowledge, attitude, and practice on generic drugs among teaching faculties at a tertiary care teaching hospital in South Gujarat, India. Natl J Physiol Pharm Pharmacol 2018;1:84-92.

Gupta R, Malhotra A, Malhotra P. A study on assessment of awareness on generic drugs among doctors in a tertiary care teaching hospital in North India. Int J Res Med Sci 2018;6:1362-7.

Zaverbhai KD, Dilipkumar KJ, Kalpan DC, Kiran DM. Knowledge, attitude and practice of resident doctors for use of generic medicines at a tertiary care hospital. J Young Pharm 2017;9:263-6.

Patel HJ, Paras R. Perceived quality of medical practitioners towards generic medicine: An exploratory investigation. J Manage Res Aanal 2016;3:101-9.

Kshirsagar MJ, Langade D, Patil S, Patki PS. Prescribing patterns among medical practitioners in Pune, India. Bull World Health Organ 1998;76:271-5.

Patil JR, Jaykare SC, Motghare VM, Padwal SL, Deshmukh VS. Awareness about generic drug prescription amongst practitioners: A knowledge attitude practice survey at rural set up. Int J Basic Clin Pharmacol 2016;5:707-12.

Gorantla NC, Penupothu SN. A comparative analysis of generic prescribing patterns among teaching and non-teaching clinicians in Nellore, India. Int J Basic Clin Pharmacol 2018;7:622-5.

Tripathi S, Bhattacharya S. Patient perception about generic vs. Branded medicines prescribed in a tertiary care hospital in Northern India-a descriptive study. Indian J Pharm Pract 2018;11:91-5.

Lagarce L, Lusson-Brisset C, Bruhat C, Diquet B, Lainé-Cessac P. How practitioners view generic drugs: An opinion study from general practitioners in Maine-et-Loire (France). Therapie 2005;60:67-74.

Gossell-Williams M. Generic substitutions: A 2005 survey of the acceptance and perceptions of physicians in Jamaica. West Indian Med J 2007;56:458.

Toverud EL, Hartmann K, Haakonsen H. A systematic review of physicians’ and pharmacists’ perspectives on generic drug use: What are the global challenges? Appl Health Econ Health Policy 2015;13:35-45.

Dixit A, Kumar N, Kumar S. Use of generic medicines: Challenges and benefits. J Health Manag 2018;20:84-90.