IN VITRO ANALYSIS OF PHYTOCHEMICAL SCREENING AND ANTIMICROBIAL ACTIVITY OF PARTHENIUM HYSTEROPHORUS L. AGAINST PATHOGENIC MICROORGANISMS

Abstract

An extract from the Parthenium hysterophorus L. leaves were screened for their phytochemical constituents and its antimicrobial activity against clinical isolates of bacterial and fungal cultures. Bacterial culture includes both Gram positive and Gram negative bacterium. The solvent used for the study was methanol. Phytochemical screening revealed the presence of Alkaloids, Carbohydrates, Cardiac Glycosides, Flavonoids, Glycosides, Phenols, Proteins, Saponins, Terpenoids, Tannins and Steroids. Agar well diffusion method was used to test the antimicrobial activity of both the standard antibiotic and plant extract. The antimicrobial activity exhibited by the methanol leaf extract has shown significant potential in inhibiting various pathogens.