COMPARATIVE STUDY OF THE EFFECT OF SUPEROXIDE SOLUTION VERSUS CHLORHEXIDINE GLUCONATE SOLUTION IN SURGICAL WOUND DRESSING

Authors

  • BHUPINDER SINGH WALIA Department of Surgery, Government Medical College, Amritsar, Punjab, India.
  • PANKAJ DUGG Department of Surgery, Government Medical College, Amritsar, Punjab, India. https://orcid.org/0000-0002-6971-1287
  • KESHAV PALIWAL Department of Surgery, Government Medical College, Amritsar, Punjab, India.
  • SANJEEV SHARMA Department of Surgery, Government Medical College, Amritsar, Punjab, India.
  • ASHWANI KUMAR Department of Surgery, Government Medical College, Amritsar, Punjab, India.

DOI:

https://doi.org/10.22159/ajpcr.2022.v15i2.43733

Keywords:

Wound healing, Superoxides, Chlorhexidine gluconate

Abstract

Objective: The objective of the study is to compare the effect of superoxide solution (SOD) and chlorhexidine gluconate on wound healing.

Methods: Hundred patients with different types of wounds were recruited in this study and randomized to two groups: Group A- SOD group and Group B- Chlorhexidine group. Observations were made regarding type of wounds, reduction of edema, culture of wounds, improvement, cure rates, and hospital stay.

Results: Although there were no significant difference in the reduction of edema and swelling of wound in both groups, the cure rates were statistically better with SOD (p=0.001) and hospital stay was also less with the use of SOD (p=0.006).

Conclusion: SOD treated case showed less morbidity, with more improvement, and more cure rate compared to chlorhexidine solution with statistically significant p-value. However, further research into the use of SOD and the cytotoxic nature of chlorhexidine in the treatment of various wounds is required.

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Author Biographies

BHUPINDER SINGH WALIA, Department of Surgery, Government Medical College, Amritsar, Punjab, India.

Associate Professor, Department of Surgery

PANKAJ DUGG, Department of Surgery, Government Medical College, Amritsar, Punjab, India.

Assistant Professor, Department of Surgery

KESHAV PALIWAL, Department of Surgery, Government Medical College, Amritsar, Punjab, India.

Senior Resident, Department of Surgery

SANJEEV SHARMA, Department of Surgery, Government Medical College, Amritsar, Punjab, India.

Professor, Department of Surgery

ASHWANI KUMAR, Department of Surgery, Government Medical College, Amritsar, Punjab, India.

Professor, Department of Surgery

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Published

07-02-2022

How to Cite

WALIA, B. S., P. DUGG, K. PALIWAL, S. SHARMA, and A. KUMAR. “COMPARATIVE STUDY OF THE EFFECT OF SUPEROXIDE SOLUTION VERSUS CHLORHEXIDINE GLUCONATE SOLUTION IN SURGICAL WOUND DRESSING”. Asian Journal of Pharmaceutical and Clinical Research, vol. 15, no. 2, Feb. 2022, pp. 82-85, doi:10.22159/ajpcr.2022.v15i2.43733.

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