PRACTICE OF SELF-MEDICATION AND QUALITY OF LIFE ASSESSMENT AMONG HEALTHCARE WORKERS OF A TERTIARY HOSPITAL IN ASSAM DURING COVID-19 PANDEMIC

Authors

  • SIDDHARTHA KRISHNA DEKA Department of Pharmacology, Gauhati Medical College and Hospital, Guwahati, Assam, India
  • LAKHIMI BORAH Department of Pharmacology, Gauhati Medical College and Hospital, Guwahati, Assam, India.
  • RIPUNJOY SARMAH Department of Pharmacology, Gauhati Medical College and Hospital, Guwahati, Assam, India. https://orcid.org/0000-0002-4820-2504

DOI:

https://doi.org/10.22159/ajpcr.2022.v15i8.44928

Keywords:

COVID-19, Self-Medication, Quality of life, Mental health assessment, Burnout

Abstract

Objectives: The aims of this study were to collect sociodemographic, clinical data regarding practice of self-medication and to assess quality of life in healthcare workers involved taking care of COVID-19 patients.

Methods: The study population consisted of 104 healthcare workers from Gauhati Medical College and Hospital directly involved in management and control of COVID-19 Pandemic. It was a cross-sectional observational study using non-probability sampling. Data were collected in a questionnaire developed by the investigators which included age, sex, and occupation, COVID-19 such as symptoms, medicines used, contraction and confirmation of COVID-19 positive, and self-medication when COVID positive, symptomatic relief, and adverse effects and usefulness of self-medication. The data for mental health were obtained in a questionnaire based on the Professional Quality of Life Scale (Compassion Satisfaction and Compassion Fatigue Version 5) with responses rated on a five-point Likert scale.

Results: The study consisted of 104 participants. Males were n=42 (40%) and females were n=62 (60%). Doctors n=20 (19%), Laboratory Technicians n=22 (21%), Nurses n=44 (42%), Pharmacists n=13 (13%), Ward boys n=3 (3%), and Ward girls n=2 (2%) took part. Eighty-four (97.7%) respondents took paracetamol, 39 (45.3%) took cough syrup, 30 (34.9%) used nasal decongestants, 25 (29.1%) utilized throat gargle, 24 (27.9%) used azithromycin, 22 (25.6%) used cefixime, 13 (15.1%) took amoxyclav, 27 (31.4%) took ORS, 3 (3.5%) took Doxycycline, 4 (4.8%) used Ivermectin, 1 (1.2%) took Dexamethasone, and 1 (1.2%) used Multivitamin. About 68% (n=51) of COVID Positive respondents self-medicated with Azithromycin, 24% (n=18) with Ivermectin, 41.3% (n=31) with Doxycycline, 20% (n=15) with Dexamethasone, and 4% (n=3) with Levocetrizine and Paracetamol. The Mental Health Assessment Scores were obtained as the sum total of scores of answers to the 30 questions provided per respondent. About 7% (n=7) respondents with total score between 60 and 69, 12% (n=13) from 70 to 79, 29% (n=30) from 80 to 89, 22% (n=23) from 90 to 99, 16% (n=17) from 100 to 109, 13% (n=13) from 110 to 119, and 1% (n=1) between 120 and 129. This indicates that some participants had mild burnout, most had moderate burnout, and a few had severe burnout.

Conclusion: Self-medication practices common among healthcare workers, increased during the COVID-19 Pandemic which must be appropriately managed to stay away from the ill effects. Providing adequate mental health resources and education to the affected health workers will motivate them increasing their productivity during the pandemic.

Downloads

Download data is not yet available.

Author Biographies

LAKHIMI BORAH, Department of Pharmacology, Gauhati Medical College and Hospital, Guwahati, Assam, India.

Assistant Professor, Department of Pharmacology, Gauhati Medical College and Hospital, Guwahati-781032, Assam

RIPUNJOY SARMAH, Department of Pharmacology, Gauhati Medical College and Hospital, Guwahati, Assam, India.

Senior Resident, Department of Pharmacology, Gauhati Medical College and Hospital, Guwahati- 781032, Assam

References

Alia E, Grant-Kels JM. Does hydroxychloroquine combat COVID-19? A timeline of evidence. J Am Acad Dermatol 2020;83:e33-4. doi: 10.1016/j.jaad.2020.04.031, PMID 32283236.

World Health Organization. Guidelines for the Regulatory Assessment of Medicinal Products for use in Self-Medication. Geneva: World Health Organization; 2000.

Eticha T, Mesfin K. Self-medication practices in Mekelle, Ethiopia. PLoS One 2014;9:e97464. doi: 10.1371/journal.pone.0097464, PMID 24820769.

Afridi MI, Rasool G, Tabassum R, Shaheen M, Siddiqullah, Shujauddin M. Prevalence and pattern of self-medication in Karachi: A community survey. Pak J Med Sci 2015;31:1241-5. doi: 10.12669/ pjms.315.8216, PMID 26649022.

Noone J, Blanchette CM. The value of self-medication: Summary of existing evidence. J Med Econ 2018;21:201-11. doi: 10.1080/13696998.2017.1390473, PMID 28994329.

Yang Y. Use of herbal drugs to treat COVID-19 should be with caution. Lancet 2020;395:1689-90. doi: 10.1016/S0140-6736(20)31143-0, PMID 32422123.

Erku DA, Belachew SA, Abrha S, Sinnollareddy M, Thomas J, Steadman KJ, et al. When fear and misinformation go viral: Pharmacists’ role in deterring medication misinformation during the ’infodemic’ surrounding COVID-19. Res Soc Admin Pharm 2020;17:1954-63.

Onchonga D. A google trends study on the interest in self-medication during the 2019 novel coronavirus (COVID-19) disease pandemic. Saudi Pharm J 2020;28:903-4. doi: 10.1016/j.jsps.2020.06.007, PMID 32641903.

Sanders JM, Monogue ML, Jodlowski TZ, Cutrell JB. Pharmacologic treatments for coronavirus disease 2019 (COVID-19): A review. JAMA 2020;323:1824-36. doi: 10.1001/jama.2020.6019, PMID 32282022.

Lam S, Lombardi A, Ouanounou A. COVID-19: A review of the proposed pharmacological treatments. Eur J Pharmacol 2020;886:173451. doi: 10.1016/j.ejphar.2020.173451, PMID 32768505.

WHO Solidarity Trial Consortium, Pan H, Peto R, Henao-Restrepo AM, Preziosi MP, Sathiyamoorthy V, Karim QA, et al. Repurposed antiviral drugs for Covid-19-interim WHO solidarity trial results. N Engl J Med 2021;384:497-511. doi: 10.1056/NEJMoa2023184, PMID 33264556.

Kim MS, An MH, Kim WJ, Hwang TH. Comparative efficacy and safety of pharmacological interventions for the treatment of COVID-19: A systematic review and network meta-analysis. PLoS Med 2020;17:e1003501. doi: 10.1371/journal.pmed.1003501, PMID 33378357.

Ng TS, Leblanc K, Yeung DF, Tsang TS. Medication use during COVID-19: Review of recent evidence. Can Fam Physician 2021;67:171-9. doi: 10.46747/cfp.6703171, PMID 33727376.

Recovery Collaborative Group, Horby P, Mafham M, Linsell L, Bell JL, Staplin N, Emberson JR, et al. Effect of hydroxychloroquine in hospitalized patients with Covid-19. N Engl J Med 2020;383:2030-40. doi: 10.1056/NEJMoa2022926, PMID 33031652.

Furtado RH, Berwanger O, Fonseca HA, Corrêa TD, Ferraz LR, Lapa MG, et al. Azithromycin in addition to standard of care versus standard of care alone in the treatment of patients admitted to the hospital with severe COVID-19 in Brazil (COALITION II): A randomised clinical trial. Lancet 2020;396:959-67. doi: 10.1016/ S0140-6736(20)31862-6, PMID 32896292.

Hinks TS, Cureton L, Knight R, Wang A, Cane JL, Barber VS, et al. Azithromycin versus standard care in patients with mild-to-moderate COVID-19 (ATOMIC2): An open-label, randomised trial. Lancet Respir Med 2021;9:1130-40. doi: 10.1016/S2213-2600(21)00263-0, PMID 34252378.

Oldenburg CE, Pinsky BA, Brogdon J, Chen C, Ruder K, Zhong L, et al. Effect of oral azithromycin vs placebo on COVID-19 symptoms in outpatients with SARS-CoV-2 infection: A randomized clinical trial. JAMA 2021;326:490-8. doi: 10.1001/jama.2021.11517, PMID 34269813.

Principle Trial Collaborative Group. Azithromycin for community treatment of suspected COVID-19 in people at increased risk of an adverse clinical course in the UK (PRINCIPLE): A randomised, controlled, open-label, adaptive platform trial. Lancet 2021;397:1063-74. doi: 10.1016/S0140-6736(21)00461-X, PMID 33676597.

Johnson RM, Vinetz JM. Dexamethasone in the management of COVID-19. BMJ 2020;370:m2648. doi: 10.1136/bmj.m2648, PMID 32620554.

World Health Organization. Coronavirus disease (COVID-19) Advice for the Public: Mythbusters. Geneva: World Health Organization Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/advic e-for-publi c/mythbusters.

Hughes CM, McElnay JC, Fleming GF. Benefits and risks of self-medication. Drug Saf 2001;24:1027-37. doi: 10.2165/00002018- 200124140-00002, PMID 11735659.

Pfefferbaum B, North CS. Mental health and the Covid-19 pandemic. N Engl J Med 2020;383:510-2. doi: 10.1056/NEJMp2008017, PMID 32283003.

United Nations. COVID-19 and the Need for Action on Mental Health. New York: United Nations; 2020.

Nicola M, Alsafi Z, Sohrabi C, Kerwan A, Al-Jabir A, Iosifidis C, et al. The socio-economic implications of the coronavirus and COVID-19 pandemic: A review. Int J Surg 2020;78:185-93. doi: 10.1016/j. ijsu.2020.04.018, PMID 32305533.

Holmes EA, O’Connor RC, Perry VH, Tracey I, Wessely S, Arseneault L, et al. Multidisciplinary research priorities for the COVID-19 pandemic: A call for action for mental health science. Lancet Psychiatry 2020;7:547-60. doi: 10.1016/S2215-0366(20)30168-1, PMID 32304649.

Chaves C, Castellanos T, Abrams M, Vazquez C. The impact of economic recessions on depression and individual and social well-being: the case of Spain (2006-2013). Soc Psychiatry Psychiatr Epidemiol 2018;53:977-86. doi: 10.1007/s00127-018-1558-2, PMID 29992341.

Granados JA, Christine PJ, Ionides EL, Carnethon MR, Roux AV, Kiefe CI, et al. Cardiovascular risk factors, depression, and alcohol consumption during joblessness and during recessions among young adults in CARDIA. Am J Epidemiol 2018;187:2339-45. doi: 10.1093/ aje/kwy127, PMID 29955769.

Beaglehole B, Mulder RT, Frampton CM, Boden JM, Newton- Howes G, Bell CJ. Psychological distress and psychiatric disorder after natural disasters: Systematic review and meta-analysis. Br J Psychiatry 2018;213:716-22. doi: 10.1192/bjp.2018.210, PMID 30301477.

Hossain MM, Sultana A, Purohit N. Mental health outcomes of quarantine and isolation for infection prevention: A systematic umbrella review of the global evidence. Epidemiol Health 2020;42:e2020038. doi: 10.4178/epih.e2020038, PMID 32512661.

Brooks SK, Webster RK, Smith LE, Woodland L, Wessely S,Greenberg N, et al. The psychological impact of quarantine and how to reduce it: rapid review of the evidence. Lancet 2020;395:912-20. doi: 10.1016/S0140-6736(20)30460-8, PMID 32112714.

Adams JG, Walls RM. Supporting the health care workforce during the COVID-19 global epidemic. JAMA 2020;323:1439-40. doi: 10.1001/ jama.2020.3972. PMID 32163102.

Sultana A, Sharma R, Hossain M, Bhattacharya S, Purohit N. Burnout among healthcare providers during COVID-19 pandemic: Challenges and evidence-based interventions. Indian J Med Ethics 2020;4:1-6.

Pappa S, Ntella V, Giannakas T, Giannakoulis VG, Papoutsi E, Katsaounou P. Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: A systematic review and meta-analysis. Brain Behav Immun 2020;88:901-7.

Lai J, Ma S, Wang Y, Cai Z, Hu J, Wei N, et al. Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019. JAMA Netw Open 2020;3:e203976. doi: 10.1001/jamanetworkopen.2020.3976, PMID 32202646.

Rossi R, Socci V, Pacitti F, Di Lorenzo G, Di Marco A, Siracusano A, et al. Mental health outcomes among front and second line health workers associated with the COVID-19 pandemic in Italy. Netw Open 2020;3:e2010185.

Patel RS, Bachu R, Adikey A, Malik M, Shah M. Factors related to physician burnout and its consequences: A review. Behav Sci (Basel) 2018;8:98. doi: 10.3390/bs8110098, PMID 30366419.

Jun J, Tucker S, Melnyk B. Clinician mental healthy and well- being during global healthcare crisis: Evidence learned from prior epidemics for COVID-19 pandemic. Worldviews Evid Based Nurs 2020;17:182-4.

Huang J, Liu F, Teng Z, Chen J, Zhao J, Wang X, et al. Care for the psychological status of frontline medical staff fighting against COVID-19. Clin Infect Dis 2020;71:3268-9.

Weaver MD, Landrigan CP, Sullivan JP, O’Brien CS, Qadri S, Viyaran N, et al. The association between resident physician work-hour regulations and physician safety and health. Am J Med 2020;133:e343-54. doi: 10.1016/j.amjmed.2019.12.053, PMID 32061733.

Walton M, Murray E, Christian MD. Mental health care for medical staff and affiliated healthcare workers during the COVID-19 pandemic. Eur Heart J Acute Cardiovasc Care 2020;9:241-7. doi: 10.1177/2048872620922795, PMID 32342698.

Figueiras A, Caamaño F, Gestal-Otero JJ. Sociodemographic factors related to self-medication in Spain. Eur J Epidemiol 2000;16:19-26. doi: 10.1023/a:1007608702063, PMID 10780338.

Onchonga D, Omwoyo J, Nyamamba D. Assessing the prevalence of self-medication among healthcare workers before and during the 2019 SARS-CoV-2 (COVID-19) pandemic in Kenya. Saudi Pharm J 2020;28:1149-54. doi: 10.1016/j.jsps.2020.08.003, PMID 32837218.

Barros AR, Griep RH, Rotenberg L. Self-medication among nursing workers from public hospitals. Rev Latino-Am Enfermagem 2009;17:1015-22. doi: 10.1590/S0104-11692009000600014.

Faqihi AH, Sayed SF. Self-medication practice with analgesics (NSAIDs and acetaminophen), and antibiotics among nursing undergraduates in university college Farasan Campus, Jazan University, KSA. Ann Pharm Fr 2021;79:275-85. doi: 10.1016/j.pharma.2020.10.012, PMID 33098875.

Gutema GB, Gadisa DA, Kidanemariam ZA, Berhe DF, Berhe AH, Hadera MG, et al. Self-medication practices among health sciences students: The case of Mekelle University. J Appl Pharm Sci 2011;1:183-9.

Nasir M, Chowdhury AS, Zahan T. Self-medication during COVID-19 outbreak: A cross sectional online survey in Dhaka city. Int J Basic Clin Pharmacol 2020;9:1325-30. doi: 10.18203/2319-2003.ijbcp20203522.

Shankar PR, Partha P, Shenoy N. Self-medication and nondoctor prescription practices in Pokhara valley, Western Nepal: A questionnaire based study. BMC Fam Pract 2002;3:17. doi: 10.1186/1471-2296-3-17, PMID 12236905.

Auta A, Omale S, Folorunsho TJ, David S, Banwat SB. Medicine vendors: Self-medication practices and medicine knowledge. N Am J Med Sci 2012;4:24-8. doi: 10.4103/1947-2714.92899, PMID 22393544.

Calva J, Bojalil R. Antibiotic use in a periurban community in Mexico: A household and drugstore survey. Soc Sci Med 1996;42:1121-8. doi: 10.1016/0277-9536(95)00385-1, PMID 8737429.

Bennadi D. Self-medication: A current challenge. J Basic Clin Pharm 2013;5:19-23. doi: 10.4103/0976-0105.128253, PMID 24808684.

Quispe-Cañari JF, Fidel-Rosales E, Manrique D, Mascaró-Zan J, Huamán-Castillón KM, Chamorro-Espinoza SE, et al. Chamorro self-medication practices during the COVID-19 pandemic among the adult population in Peru: A cross-sectional survey. Saudi Pharm J 2021;29:1-11. doi: 10.1016/j.jsps.2020.12.001, PMID 33519270.

Miñan-Tapia A, Conde-Escobar A, Calderon-Arce D, Cáceres- Olazo D, Peña-Rios AJ, Donoso-Romero RC. Associated Factors to Self-Medication with Drugs Related to COVID-19 in Health Science Students from a Peruvian city. SciELO; 2020. https://doi.org/10.1590/ SciELOPreprints.1225.

Berreni A, Montastruc F, Bondon-Guitton E, Rousseau V, Abadie D, Durrieu G, et al. Adverse drug reactions to self-medication: A study in a pharmacovigilance database. Fundam Clin Pharmacol 2015;29:517-20. doi: 10.1111/fcp.12140, PMID 26215671.

Gras M, Gras-Champel V, Moragny J, Delaunay P, Laugier D, Masmoudi, et al. Impact of the COVID-19 outbreak on the reporting of adverse drug reactions associated with self-medication. Ann Pharm Fr 2021;79:522-9. doi: 10.1016/j.pharma.2021.02.003. PMID 33631179, PMCID PMC7899020.

James H, Handu SS, Al Khaja KA, Otoom S, Sequeira RP. Evaluation of the anowledge, attitude and practice of self-medication among first-year medical students. Med Princ Pract 2006;15:270-5. doi: 10.1159/000092989, PMID 16763393.

Kayalvizhi S, Senapathi R. Evaluation of the perception, attitude and practice of self-medication among business students in three selected cities, south India. Int J Enterpr Innov Manag Stud 2010;1:40-4.

Abay SM, Amelo W. Assessment of self-medication practices among medical, pharmacy, and health science students in Gondar University. Ethiopia. J Young Pharm 2010;2:306-10. doi: 10.4103/0975- 1483.66798, PMID 21042491.

Saeed MS, Alkhoshaiban AS, Al-Worafi YM, Long CM. Perception of self-medication among university students in Saudi Arabia. Arch Pharm Pract 2015;5:149.

AlBasheer OB, Mahfouz MS, Masmali BM, Ageeli RA, Majrashi AM, Hakami AN, et al. Self-medication practice among undergraduate medical students of a Saudi tertiary institution. Trop J Pharm Res 2016;15:2253-9. doi: 10.4314/tjpr.v15i10.26.

Alshahrani SM, Alavudeen SS, Alakhali KM, Al-Worafi YM, Bahamdan AK, Vigneshwaran E. Self-medication among King Khalid University students, Saudi Arabia. Risk Manag. Health Care Policy 2019;12:243-9.

Williams A, Crawford K. Self-medication practices among undergraduate nursing and midwifery students in Australia: A cross-sectional study. Contemp Nurse 2016;52:410-20. doi: 10.1080/10376178.2016.1197782, PMID 27278099.

Gama AS, Secoli SR. Self-medication among nursing students in the state of Amazonas Brazil. Rev Gaucha Enferm 2017;38:e65111. doi: 10.1590/1983-1447.2017.01.65111, PMID 28538809.

Malak MZ, Kamel AM. Self-medication practices among university students in Jordan, Malay. J Health Sci 2019;15:112-9.

Gras M, Champel V, Masmoudi K, Liabeuf S. Self-medication practices and their characteristics among French university students. Therapie 2020;75:419-28. doi: 10.1016/j.therap.2020.02.019, PMID 32204933.

Chua SE, Cheung V, Cheung C, McAlonan GM, Wong JW, Cheung EP, et al. Psychological effects of the SARS outbreak in Hong Kong on high-risk health care workers. Can J Psychiatry 2004;49:391-3. doi: 10.1177/070674370404900609, PMID 15283534.

West CP, Dyrbye LN, Shanafelt TD. Physician burnout: Contributors, consequences and solutions. J Intern Med 2018;283:516-29. doi: 10.1111/joim.12752, PMID 29505159.

Gold JA. Covid-19: Adverse mental health outcomes for healthcare workers. BMJ 2020;369:m1815. doi: 10.1136/bmj.m1815, PMID 32371465.

Published

07-08-2022

How to Cite

DEKA, S. K., L. BORAH, and R. SARMAH. “PRACTICE OF SELF-MEDICATION AND QUALITY OF LIFE ASSESSMENT AMONG HEALTHCARE WORKERS OF A TERTIARY HOSPITAL IN ASSAM DURING COVID-19 PANDEMIC”. Asian Journal of Pharmaceutical and Clinical Research, vol. 15, no. 8, Aug. 2022, pp. 184-9, doi:10.22159/ajpcr.2022.v15i8.44928.

Issue

Section

Original Article(s)