A SYSTEMATIC REVIEW ON OXALIS CORNICULATA LINN. A CROP FIELD WEED WITH PROMISING PHARMACOLOGICAL ACTIVITIES

SUMAN KUMAR MEKAP; SAGAR KUMAR MISHRA; PRASANA KUMAR PANDA; SAGAR SUMAN PANDA; DEEPAK KUMAR SARANGI

doi:10.22159/ajpcr.2022.v15i8.45017

Authors

SUMAN KUMAR MEKAP Department of Pharmacology, Centurion University of Technology and Management, Odisha, India. https://orcid.org/0000-0001-9749-0648
SAGAR KUMAR MISHRA Department of Pharmacognosy, University Department of Pharmaceutical Sciences, Utkal University, Bhubaneswar, Odisha, India.
PRASANA KUMAR PANDA Department of Pharmacology, Gracious College of Pharmacy, Raipur, India.
SAGAR SUMAN PANDA Department of Pharmacy, Roland Institute of Pharmaceutical Sciences, Brahmapur, Odisha, India.
DEEPAK KUMAR SARANGI Department of Pharmacy, Roland Institute of Pharmaceutical Sciences, Brahmapur, Odisha, India.

DOI:

https://doi.org/10.22159/ajpcr.2022.v15i8.45017

Keywords:

Oxalis corniculata, Methoxy-flavones, Pharmacological activities, Antinociceptive, Antidiabetic

Abstract

Various ailments were known to being treated and cured by several herbs either as a main ingredient or being associated with different medical systems. One such clinically significant and endangered crop field weed is Oxalis corniculata Linn. which is generally found in subtropical and tropical regions across the globe. The medicinal significance of this weed is well evidenced in medicinal scriptures such as Ayurveda, Siddha, Unani, and compendiums of India, China, Britain, and America. The present review highlights on some of the crucial phytoconstituents such as flavonoids, tannins, glycosides, and fatty acids isolated from the said plant and their medicinal applications for treating conditions such as inflammation, anxiety, cancer, and diabetes. Further, the review stresses the future scope for therapeutic applications of these specific phytoconstituents of O. corniculata and the need for its research and development.

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References

Dubey NK, Kumar R, Tripathi P. Global promotion of herbal medicines: India’s apportunity. Curr Sci 2004;5:37-41.

Cox PA, Balick MJ. The ethnobotanical approach to drug discovery. Sci Am 1994;270:82-7. doi: 10.1038/scientificamerican0694-60, PMID 8023119

Sharma RA, Kumari A. Phytochemistry, pharmacology and therapeutic application of Oxalis corniculata linn. A review. Int J Pharm Pharm Sci 2014;6:975-1491.

The Wealth of India: N-P:259. Vol. 4. New Delhi: Council of Scientific and Industrial Research; 2013.

Houghton PJ. The role of plants in traditional medicine and current therapy. J Altern Complement Med 1995;1:131-43. doi: 10.1089/ acm.1995.1.131, PMID 9395610

Fransworth NR. Ethinopharmacology and future drug development: The North American experience. J Ethinopharmacol 1993;38:45-52.

Bohlin L, Göransson U, Alsmark C, Wedén C, Backlund A. Natural products in modern life science. Phytochem Rev 2010;9:279-301. doi: 10.1007/s11101-009-9160-6, PMID 20700376

Sukhder V. Ethanotherapeutics and modern drug development. The potential Ayurveda. Curr Sci 1997;73:909-28.

Butler MS. The role of natural product chemistry in drug discovery. J Nat Prod 2004;67:2141-53. doi: 10.1021/np040106y, PMID 15620274

Johansen DA. Plant Micro Technique. New York: McGraw-Hill Book Co.; 1940. p. 52.

Cordell GA. Sustainable medicines and global health care. Planta Med 2011;77:1129-38. doi: 10.1055/s-0030-1270731, PMID 21308611

Tripathi L, Tripathi JN. Role of biotechnology in medicinal plants. Trop J Pharm Res 2003;2:243-53. doi: 10.4314/tjpr.v2i2.14607

Turner RA, Hebborn P. Secreening Methods in Pharmacology. United States: Academic Press; 1971. p. 14-32.

Burgen AS, Mitchell JF. Goddum’s Pharmacology. Oxford: Oxford University Press; 1977. p. 110.

Tanaka JC, Silva CC, Oliveira AJ, Nakamura CV, Dias Filho BP. Antibacterial activity of indole alkaloids from Aspidosperma ramiflorum. Braz J Med Biol Res 2006;39:387-91. doi: 10.1590/s0100- 879x2006000300009, PMID 16501818

Saxena HO, Brahmam M. Flora of Orissa. Vol. 1. Odisha: Council of Scientific and Industrial Research (India) Regional Research Laboratory (Bhubaneswar, India), Orissa Forest Development Corporation. 1994. p. 220-1.

Hemant B, Mukesh S, Deepa T, Tapan KG, Tripathi DK. The botany, chemistry, pharmacological and therapeutic application of Oxalis corniculata Linn-a review. Int J Phytomed 2011;3:1-8.

David Hall W, Vernon Vandiver V, Brent Sellers A. Creeping wood sorrel, Oxalis corniculata L. Florida: Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida; 1996. p. 1-2.

Mary Z, Vasanthakumar KG, Pasupathy S, Bikshapathi T. Pharmacognostical studies on Oxalis corniculata Linn. (Oxalidaceae). Anc Sci Life 2001;21:1-8.

Available from: http://www.ayurvedaconsultants.com/images/doctor/ ayurveda/ayurvedic-herb-changeri.aspx

Available from: http://www.indianmedicinalplants.info/Medicinal- Plants/Oxalis-corniculata-Changeri-Indian-medicinal-plants- Ayurveda.html

The Ayurvedic Pharmacopoieia of India, Part I. India: Government of India; 1940. p. 36-8.

Kumar KA, Kuntal D, Manan J, Nishith M. Oxalis corniculata Linn. The Plant of Indian Subtropics. Industry: Herbal Tech; 2010. p. 7-11.

Satapathy KB, Sahu BB, Jena G. Crop weeds diversity and their ethnomedicinal uses in the treatment of common ailments in Jajpur district of Odisha (India). Int J Arom Plants. 2012;2:80-9.

Toba S. A Study in Ethnobotany and Village Economy. Bhutan: Khaling Plant Names; 2018. p. 147-69.

Narayan PM. Ethnobotanical note on folk-lore remedies of baglung district Nepal. CNAS J 1993;20:184-96.

Focho DA, Nkeng EA, Lucha CF. Ndam WT, Fegenui A. Ethnobotanical survey of plants used to treat diseases of the reproductive system and preliminary phytochemical screening of some species of Malvaceae in Central Sub-division, Cameroon. J Med Plants Res 2009;3:301-14.

Achutanand S, Srivatsava S, Rawat AK. An ethnobotanical study on medicinal plants of Rewa district, Madhya Pradesh. Indian J Madhya Pradesh 2008;9:191-202.

Basumatary SK. Ahmed MJ, Deka SP. Some medicinal plant leaves used by boro (tribal) people of Goalpara district. Assam. Nat Prod Radiance 2004;3:88-90.

Taranalli AD, Tipare SV, Kumar S. Wound healing activity of Oxalis corniculata whole plant extract in rats. Indian J Pharm Sci 2004;66:444-6.

Jyothi KS, Hemadatha P, Suresh S. Evaluation of α-amylase inhibitory potential of three medicinally important traditional wild food plants in India. Int J Green Pharm 2011;5:95-9.

Manna D, Dutta PK, Achari B, Lohia AA. Novel galacto-glycerolipid from Oxalis corniculata kills Entamoeba histolytica and Giardia lamblia. Antimicrob Agents Chemother 2010;54:4825-32. doi: 10.1128/ AAC.00546-10, PMID 20713666

Mahadik J, Patil SB, Nilofar SN. Evaluation of antiulcer activity aqueous and methanolic extract of Oxalis corniculata leaf in experimental rats. Int J Pharm Res Dev 2011;3:98-104.

Sachin SS, Archana RJ, Manoj NG. In-vitro antioxidant and anti-inflammatory activity of methanolic extract of Oxalis corniculata. Int J Pharm Pharm Sci 2010;2:146-55.

Kuntal D, Kathiriya AK, Kumar EP, John BM. Evaluation of hepatoprotective activity of aqueous and ethanolic extract of Oxalis corniculata against intoxication of thioacetamide induced rats. 2012;22:412-7.

Verma RK, Chaurasia L, Katiyar S. Potential antifungal plants for controlling building fungi. Nat Prod Radiance 2008;7:374-87.

Abhilash PA, Nilasha PA, Suresh V. Cardioprotective effects of aqueous extract of Oxalis corniculata in experimental myocardial infarction. Exp Toxicol Pathway 2011;63:535-40.

Joppa LN, Roberts DL, Myers NP, Pimm SL. Biodiversity hotspots house most undiscovered plant species. Proc Natl Acad Sci U S A 2011;108:13171-6. doi: 10.1073/pnas.1109389108, PMID 21730155

Basu T, Mallik A, Mandal N. Evolving importance of anticancer research using herbal medicine: A scientometric analysis. Scientometrics 2017;110:1375-96. doi: 10.1007/s11192-016-2223-8

Lee JA, Uhlik MT, Moxham CM, Tomandl D, Sall DJ. Modern phenotypic drug discovery is a viable, neoclassic pharma strategy. J Med Chem 2012;55:4527-38. doi: 10.1021/jm201649s, PMID 22409666

Lee ML, Schneider G. Scaffold architecture and pharmacophoric properties of natural products and trade drugs: Application in the design of natural product-based combinatorial libraries. J Comb Chem 2001;3:284-9. doi: 10.1021/cc000097l, PMID 11350252

Kunwar RM, Uprety Y, Burlakoti C, Chowdhary CL, Bussmann RW. Indigenous use and ethnopharmacology of medicinal plants in far-west Nepal. Ethnobot Res Appl 2009;7:5-28. doi: 10.17348/era.7.0.5-28

Pimm SL, Jenkins CN, Abell R, Brooks TM, Gittleman JL, Joppa LN, et al. The biodiversity of species and their rates of extinction, distribution, and protection. Science 2014;344:1246752. doi: 10.1126/ science.1246752, PMID 24876501

Adam B, Katarzyna Z, Iwona W, Katarzyna P. Antioxidant properties of medicinal plants from Peru. Food Nutr Sci 2013;4:71-77. doi: 10.4236/ fns.2013.48A009

Abourashed EA, Koetter UK, Brattström A. In vitro binding experiments with a Valerian, hops and their fixed combination extract (Ze91019) to selected central nervous system receptors. Phytomedicine 2004;11:633- 8. doi: 10.1016/j.phymed.2004.03.005, PMID 15636177

Cox PA. Will tribal knowledge survive the millennium? Science 2000;287:44-5. doi: 10.1126/science.287.5450.44, PMID 10644221

Eckstein-Ludwig U, Webb RJ, Van Goethem ID, East JM, Lee AG, Kimura M, et al. Artemisinins target the SERCA of Plasmodium falciparum. Nature 2003;424:957-61. doi: 10.1038/nature01813, PMID 12931192

Gurib-Fakim A. Medicinal plants: traditions of yesterday and drugs of tomorrow. Mol Aspects Med 2006;27:1-93. doi: 10.1016/j. mam.2005.07.008, PMID 16105678

Khan BA, Abraham A, Leelamma S. Biochemical response in rats to the addition of curry leaf (Murraya koenigii) and mustard seeds (Brassica juncea) to the diet. Plant Foods Hum Nutr 1996;49:295-9. doi: 10.1007/ BF01091978, PMID 8983055

Subbarao D, Chandrasekhara N, Satyanarayana MN, Srinivasan M. Effect of curcumin on serum and liver cholesterol levels in cholesterol fed rats. J Nutr 1970;100:1307-15.

Kirk DD, Rempel R, Pinkhasov J, Walmsley AM. Application of Quillaja saponaria extracts as oral adjuvants for plant-made vaccines. Expert Opin Biol Ther 2004;4:947-58. doi: 10.1517/14712598.4.6.947, PMID 15174976

Boniface L, Pierre NJ, Alain AG, T, Boniface S, Philippe HR. Chemical composition and antimicrobial activities of Cinnamomum zeylanicum Blume dry Leaves essential oil against foodborne pathogens and adulterated microorganisms. Res J Biol Sci 2012;1:18-25.

Ahmad IA, Mehmood Z, Mohammad F. Screening of some Indian medicinal plants for their antimicrobial properties. J Ethnopharmacol 1998;62:183-93. doi: 10.1016/s0378-8741(98)00055-5, PMID 9741890

El-Hilaly J, Hmammouchi M, Lyoussi B. Ethnobotanical studies and economic evaluation of medicinal plants in Taounate province (Northern Morocco). J Ethnopharmacol 2003;86:149-58. doi: 10.1016/ s0378-8741(03)00012-6, PMID 12738079

Kunwar RM, Nepal BK, Kshhetri HB, Rai SK, Bussmann RW. Ethnomedicine in Himalaya: A case study from Dolpa, Humla, Jumla and Mustang districts of Nepal. J Ethnobiol Ethnomed 2006;2:27. doi: 10.1186/1746-4269-2-27, PMID 16749924

Mahmood A, Mahmood A, Shaheen H, Qureshi RA, Sangi Y, Gilani SA. Ethnomedicinal survey of plants from district Bhimber Azad Jammu and Kashmir, Pakistan. J Med Plants Res 2011;5:2348-60.

Qureshi RA, Ghufran MA, Gilani SA, Yousaf Z, Abbas G, Batool A. Indigenous medicinal plants used by local women in southern Himalayan regions of Pakistan. Pak J Bot 2009;41:19-25.

World Health Organization. Summary of WHO guidelines for the assessment of herbal medicines. Herbalgram 1993;28:13-4.

Balick MJ, Mendelsohn R. Assessing the economic value of traditional medicines from tropical rain forests. Conserv Biol 1992;6:128-30. doi: 10.1046/j.1523-1739.1992.610128.x

Planchon JE. Oxalis corniculata L. var. atropurpurea. Flore Serres Jardins Eur 1857;12:47-8.

Holm LG, Pancho JV, Herberger JP, Plucknett DL. A Geographic Atlas of World Weeds. Malabar: Krieger Publishing; 1991.

Eiten G. Taxonomy and regional variation of Oxalis section Corniculatae. I [introduction]. Am Midl Nat 1963;69:257-309. doi: 10.2307/2422912

Castillo CC, Fuller DQ, Piper PJ, Bellwood P, Oxenham M. Hunter-gatherer specialization in the Late Neolithic of southern Vietnam-the case of Rach Nui. Quat Int 2018;489:63-79. doi: 10.1016/j. quaint.2016.11.034

Barakat HN. Plant macroremains from Z’bib N Elias. A subfossil midden from a prehistoric cave in the Hoggar Central Sahara. Acta Palaeobot 1995;1:99-103.

Groom Q. Earliest Records of Oxalis corniculata by Country. 1st Version. Switzerland: Zenodo; 2018. doi: 10.5281/zenodo.1332025

Mathew PM. Cytology of oxalidaceae. Cytologia 1958;23:200-10. doi: 10.1508/cytologia.23.200

Nasu H, Gu HB, Momohara A, Yasuda Y. Land-use change for rice and foxtail millet cultivation in the Chengtoushan site, central China, reconstructed from weed seed assemblages. Archaeol Anthropol Sci 2012;4:1-14. doi: 10.1007/s12520-011-0077-9

Knuth RG. Oxalidaceae. In: Herzog T, editor. Die von Dr. Th. Herzog auf Seiner Zweiten Reise Durch Bolivien in den Jahren 1910 und 1911 Gesammelten Pflanzen. 27. Leiden: Mededeelingen van’s Rijks- Herbarium; 1915. p. 1-90.

Gupta BM, Ahmed KM, Dhawan SM, Gupta R. Aloe vera (Medicinal Plant) research: A scientometric assessment of global publications output during 2007-16. Pharmacogn J 2018;10:1-8.

de la Cruz-Lovera C, Perea-Moreno A, de la Cruz-Fernández J, Alvarez-Bermejo J, Manzano-Agugliaro F. Worldwide research on energy efficiency and sustainability in public buildings. Sustainability 2017;9:1294. doi: 10.3390/su9081294

Sambaiah K, Satyanarayana MN. Influence of red pepper and capsaicin on body composition and lipogenesis in rats. J Bio Sci 1982;4:425-30. doi: 10.1007/BF02704635

World Health Organization. WHO Monographs of Selected Medicinal Plants. Vol. 1. Geneva, Switzerland: World Health Organization; 1999.

Sreenivasan MR, Satyanarayana MN. Influence of capsaicin, eugenol, curcumin and ferulic acid on sucrose induced hypertriglyceridemia in rats. Nutr Rep Int 1988;38:571-9.

Njume C, Goduka NI. Treatment of diarrhoea in rural African communities: An overview of measures to maximise the medicinal potentials of indigenous plants. Int J Environ Res Public Health 2012;9:3911-33. doi: 10.3390/ijerph9113911, PMID 23202823

Jung M, Lee K, Kim H, Park M. Recent advances in artemisinin and its derivatives as antimalarial and antitumour agents. Curr Med Chem 2004;11:1265-84. doi: 10.2174/0929867043365233, PMID 15134519

Guo S, Kenne L. Structural studies of triterpenoid saponins with new acyl components from Quillaja saponaria Molina. Phytochemistry 2000;55:419-28. doi: 10.1016/s0031-9422(00)00340-x, PMID 11140603

Kumar S, Pandey AK. Chemistry and biological activities of flavonoids: An overview. Sci World J 2013;2013:162750.

Young SL, Chaplin DJ. Combrestatin A4 phosphate: Background and current clinical status. Expert Opin Investig Drugs 2004;13:1171-82. doi: 10.1517/13543784.13.9.1171, PMID 15330748

Cragg GM, Newman DJ. Natural products: A continuing source of novel drug leads. Biochim Biophys Acta 2013;18:3670-95.

Willcox M, Rasoanaivo P, Sharma VP, Bodeker G. Comments on: Randomised controlled trial of a traditional preparation of Artemisia annua L. (Annual Wormwood) in the treatment of malaria. Trans R Soc Trop Med Hyg 2004;98:755-6. doi: 10.1016/j.trstmh.2004.06.001, PMID 15485708

Abraham A, Kurup PA. Mechanism of hypercholesterolemia produced by biotin deficiency. J Bio Sci 1988;12:187.

Hu L, Jhoo JW, Ang CY, Dinovi M, Mattia A. Determination or 6 kavalactones in dietary supplements and selected functional foods containing Piper methysticum by isocratic liquid chromatography with internal standards. JAOAC 2005;88:16-25.

Martinez P, Contra T, Scaglione C, Diaz Perez MA, Madero Lopez L. Topotecan for paediatric patients with resistant and recurrent solid tumours. Ann Pediatr (Barc) 2003;59:143-8.

Oubré AY, Carlson TJ, King SR, Reaven GM. From plant to patient: An ethnomedical approach to the identification or new drugs for the treatment of NIDDM. Diabetologia 1997;40:614-7. doi: 10.1007/ s001250050724, PMID 9165233

Martin MT, Rasoanaivo P, Palazzino G, Galeffi C, Nicoletti M, Trigalo F, et al. Minor Nb,C(21)-secocuran alkaloids of Strychnos myrtoides. Phytochemistry 1999;51:479-86. doi: 10.1016/S0031- 9422(99)00033-3

Robbins C. Medicine from U.S. Wildlands: An Assessment of Native Plant Species Harvested in the United States for Medicinal Use and Trade and Evaluation of the Conservation and Management Implications. TRAFFIC North America. Nature Conservancy; 1999. Web Resource. Available from: http://www.nps.gov/plants/medicinal/ pubs/traffic.htm

Ahmad Khan MS, Ahmad I. Herbal Medicine: Current Trends and Future Prospects. New Look to Phytomedicine. Cambridge, MA: Academic Press; 2019. p. 3-13. doi: 10.1016/B978-0-12-814619- 4.00001-X

Anderson RC. Anderson MR, Houseman G. Wild American ginseng. Nat Plants J 2002;3:93-105.

Bierzychudek P. Life histories and demography of shade-tolerant temperate forest herbs: A review. New Phytol 1982;90:757-76. doi: 10.1111/j.1469-8137.1982.tb03285.x

Gilliam FS. The ecological significance of the herbaceous layer in forest ecosystems. J Bio Sci 2007;57:845-58. doi: 10.1641/B571007

Johnston J, Szabo M, Rodney A. Good food, good people: Understanding the cultural repertoire of ethical eating. J Consum Cult 2011;11:293- 318. doi: 10.1177/1469540511417996

Street RA, Stirk WA, Van Staden J. South African traditional medicinal plant trade-challenges in regulating quality, safety and efficacy. J Ethnopharmacol 2008;119:705-10. doi: 10.1016/j.jep.2008.06.019, PMID 18638533

Kinghorn AD, Seo EK. Plants as sources of drugs. In: Agricultural Materials as Renewable Resources. Ch. 12. Washington, DC: ACS Symposium Series; 1996. p. 179-93. doi: 10.1021/bk-1996-0647.ch012

Abbas H, Hassan VN. Chemical constituents and efficacy of Cymbopogon olivieri (BOISS). Bar essential oil against Malaria. Daru J Mol 2003;11:125-8.