PROBABILITY OF COVID-19 IN ABO BLOOD TYPE DURING SECOND WAVE IN SOUTHERN RAJASTHAN, INDIA

Authors

  • NEHA SHARMA Department of Biochemistry, Shri Atal Bihari Vajpayee Government Medical College, Faridabad, Haryana, India.
  • SOHIL TAKODARA Department of Biochemistry, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India.
  • APARAJITA KUSHWAHA Department of Biochemistry, Shri Atal Bihari Vajpayee Government Medical College, Faridabad, Haryana, India.
  • RAJU RAM Department of Biochemistry, Shri Atal Bihari Vajpayee Government Medical College, Faridabad, Haryana, India.
  • BADRI LAL JAT Department of Biochemistry, Shri Atal Bihari Vajpayee Government Medical College, Faridabad, Haryana, India.
  • SANGHAPRIYA MUKHERJEE Department of Biochemistry, Shri Atal Bihari Vajpayee Government Medical College, Faridabad, Haryana, India.
  • ASHISH SHARMA Department of Biochemistry, Shri Atal Bihari Vajpayee Government Medical College, Faridabad, Haryana, India.

DOI:

https://doi.org/10.22159/ajpcr.2022.v15i12.45685

Keywords:

ABO blood group, COVID-19, D-Dimer, Inflammatory markers, Udaipur

Abstract

Objectives: Along the course human history of scientific research, the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) is the most concerning global health problem. Second wave of COVID-19 has adversely affected India. However, India embarked on its immunization program on January 16, 2021, operating 3006 vaccination centers onset Covaxin and CoviShield. This study aimed to ascertain if there is an association amidst ABO blood type and probability of COVID-19 infection in wave.

Methods: This is analytical and observational study conducted on 713 SARS-COVID-19-positive patients of a known ABO blood type, who attended outpatient department and inpatient department during March 26–May 20, 2021, in tertiary care hospital Udaipur (Raj.) Serum inflammatory markers were evaluated by Cobas 6000.

Results: Out of the 713 patients who were tested positive, 15.56% was blood group Type A, 19.91% was blood group Type B, 13.65% was blood group Type AB, and 46.28% was blood group Type O. On statistical analysis, there were positive association between O+ blood type and peak inflammatory marker (interleukin-6 and D-Dimer). Patients with blood Type O who received a test were more likely to test positive and blood Type B+, A+, A+,AB+,O-,A-,B-, and AB- were less likely to test positive.

Conclusion: The present study shows an evidence for interrelation between ABO blood groups and SARS-COVID-19. Reported infection prevalence is moderately increased among O+ blood type individuals. Determination of level of inflammatory markers might prove to be helpful to clinicians so as to keep track of severity of infection and evaluate the prognosis of SARS-COVID-19 with specific ABO blood groups.

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Author Biographies

SOHIL TAKODARA, Department of Biochemistry, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India.

ASSOCIATE PROFESSOR

BIOCHEMISTRY

APARAJITA KUSHWAHA, Department of Biochemistry, Shri Atal Bihari Vajpayee Government Medical College, Faridabad, Haryana, India.

PG student

GMCH, udaipur

RAJU RAM, Department of Biochemistry, Shri Atal Bihari Vajpayee Government Medical College, Faridabad, Haryana, India.

PG student

GMCH, udaipur

BADRI LAL JAT, Department of Biochemistry, Shri Atal Bihari Vajpayee Government Medical College, Faridabad, Haryana, India.

pg Student

GMCH, udaipur , Rajasthan

SANGHAPRIYA MUKHERJEE, Department of Biochemistry, Shri Atal Bihari Vajpayee Government Medical College, Faridabad, Haryana, India.

PG student

GMCH, udaipur, rajasthan

ASHISH SHARMA, Department of Biochemistry, Shri Atal Bihari Vajpayee Government Medical College, Faridabad, Haryana, India.

Professor and Head

GMCH,Udaipur

References

Health the sciences. The Novel Coronavirus Variants and India’s Uncertain Future. Environment. Available from: https://www.science. thewire.in/health/sars-cov-2-variants-b117-b1617-india-second-wave-uncertain-future [Last accessed on 2021 Apr 12].

COVID-19 Vaccine Information-get Updates on COVID-19. Available from: https://www.en.wikipedia.org/wiki/COVID-19 [Last accessed on 2021 Mar 31].

Dr Chaudhary Hospital and medical Journal Hospital Centre Udaipur. Receives COVID-19 Vaccine-things You Should Know About the Coronavirus Vaccine. Available from: ??? [Last accessed on 2021 Jan 18].

Statistics JHU CSSE COVID-19 Data. Available from: https:// www.github.com/CSSEGISandData/COVID-19 [Last accessed on 2021 Mar 23].

Health Rep, Udaipur. 2021July10. 2021 July 4.

HT Correspondent. Udaipur Emerges as Covid-19 Hotspot in Rajasthan, Positivity Rate at 30%. Hindustan times 2021APR21. New Delhi: HT Correspondent. Available from: ???. [Last accessed on 2022 Apr 24].

Sharma S. AB, B Blood Groups More Susceptible to Corona Virus, Group ’O’ Least: CSIRstudy. Available from: https://www.amarujala. com/photogallery/lifestyle/fitness/coronavirus-ab-and-b-blood-groups-are-more-sensitive-to-covid-19. 2021 may Wed, 12; 09:35 PM IST. [Last accessed on 2021 May 21].

Zee News Desk. AB, B Blood Groups More Susceptible to Coronavirus, Group ’O’ Least: CSIR Study; 2021 May 11. 17.49 pm IST. Uttar Pradesh, India: Zee News Desk. Available from: https://www.zeenews. india.com/hindi/india/photo-gallery-csir-said-ab-and-b-blood-group-people-more-susceptible-for-covid-19-infection/898771 [Last accessed on 2021 May 21]

Yip SP. Sequence variation at the human ABO locus. Ann Hum Genet 2002;66:1-27. doi: 10.1017/S0003480001008995, PMID 12014997

Garratty G, Glynn SA. McEntire R, Retrovirus Epidemiology Donor Study. ABO and Rh(D) phenotype frequencies of different racial/ ethnic groups in the United States. Transfusion 2004;5:703-6. doi: 10.1111/j.1537-2995.2004.03338.x. PMID 15104651

Cheng Y, Cheng G, Chui CH, Lau FY, Chan PK, Ng MH, et al. ABO blood group and susceptibility to severe acute respiratory syndrome. JAMA 2005;293:1450-1. doi: 10.1001/jama.293.12.1450-c, PMID 15784866

Stowell CP, Stowell SR. Biologic roles of the ABH and Lewis histo-blood group antigens Part I: Infection and immunity. Vox Sang 2019;114:426-42. doi: 10.1111/vox.12787. PMID 31070258

Cooling L. Blood groups in infection and host susceptibility. Clin Microbiol Rev 2015;28:801-70. doi: 10.1128/CMR.00109-14, PMID 26085552

Mackenzie JS, Wetherall JD, Fimmel PJ, Hawkins BR, Dawkins RL. Host factors and susceptibility to influenza A infection: The effect of ABO blood groups and HL-A antigens. Dev Biol Stand 1977;39:355- 62. PMID 604120

Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study. Lancet 2020;395:1054-62. doi: 10.1016/S0140-6736(20)30566-3, PMID 32171076

Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ, et al. COVID-19: Consider cytokine storm syndromes and immunosuppression. Lancet 2020;395:1033-4. doi: 10.1016/S0140- 6736(20)30628-0, PMID 32192578

Stebbing J, Phelan A, Griffin I, Tucker C, Oechsle O, Smith D, et al. COVID-19: combining antiviral and anti-inflammatory treatments. Lancet Infect Dis 2020;20:400-2. doi: 10.1016/S1473- 3099(20)30132-8, PMID 32113509

Published

07-12-2022

How to Cite

SHARMA, N., S. TAKODARA, A. KUSHWAHA, R. RAM, B. L. JAT, S. MUKHERJEE, and A. SHARMA. “PROBABILITY OF COVID-19 IN ABO BLOOD TYPE DURING SECOND WAVE IN SOUTHERN RAJASTHAN, INDIA”. Asian Journal of Pharmaceutical and Clinical Research, vol. 15, no. 12, Dec. 2022, pp. 61-66, doi:10.22159/ajpcr.2022.v15i12.45685.

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