A STUDY ON CLINICAL PROFILE AND OUTCOME OF RODENTICIDE POISONING IN SOUTH INDIA: A CROSS-SECTIONAL STUDY

MALARVIZHI MURUGESAN; RADHAKRISHNAN NATARAJAN; PRASANNA DEVI PANDIAN; JEEVITHAN SHANMUGAM

doi:10.22159/ajpcr.2023.v16i2.46076

Authors

MALARVIZHI MURUGESAN Department of Medical Gastroenterology, KAPV Medical College and MGM GH, Trichy, Tamil Nadu, India.
RADHAKRISHNAN NATARAJAN Department of Medical Gastroenterology, KAPV Medical College and MGM GH, Trichy, Tamil Nadu, India.
PRASANNA DEVI PANDIAN Department of General Medicine, Cuddalore Government Head Quarters Hospital, Cuddalore, Tamil Nadu, India.
JEEVITHAN SHANMUGAM Department of Community Medicine, KMCH Institute of Health Sciences and Research, Coimbatore, Tamil Nadu, India. https://orcid.org/0000-0002-6289-587X

DOI:

https://doi.org/10.22159/ajpcr.2023.v16i2.46076

Keywords:

Rodenticide poisoning, Liver parameters, Clinical course, prognosis

Abstract

Objectives: The objectives of the study were to study the sociodemographic profile, clinical features, and clinical outcome of patients admitted with rat killer poison in a tertiary care hospital in South India.

Methods: A cross-sectional study was conducted among those who have been admitted with rodenticide poisoning in a tertiary care center in South India. Prior Institutional Ethical committee Permission and written informed consent were obtained. Data on sociodemographic profile were elicited. The clinical course of all those who were enrolled in the study was closely followed and monitored. All the necessary blood parameters were done on every alternate day after the admission blood investigations. The data were entered into Microsoft excel and were analyzed using PSPP software. The difference in mean blood parameters between survivors and non survivors was compared.

Results: The consumption of rodenticide poisoning was higher among females (59%). Majority (58%) were married. Vomiting was present in nearly two-third of the study population and abdominal pain in 21%. Dose ingested and time of reporting to hospital were high among non-survivors. Mean bilirubin, serum glutamic-oxaloacetic transaminase, serum glutamic pyruvic transaminase, and International normalized ratio were higher among non-survivors compared to survivors at all the days measured.

Conclusions: Monitoring of liver parameters plays a key role in assessing the prognosis of the patient and also in treating them.

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