TO STUDY THE EFFECTS OF DIFFERENT TIMING OF DELAYED CORD CLAMPING ALONG WITH MILKING ON HAEMATOLOGICAL PARAMETERS IN NEWBORNS - A RANDOMIZED CONTROL TRIAL

Authors

  • PRATIBHA PILANIA Department of Obstetrics and Gynaecology, SMS Medical College, Jaipur, Rajasthan, India.
  • URMILA MAHALA Department of PMR, SMS Medical College, Jaipur, Rajasthan, India. https://orcid.org/0000-0003-0668-1313
  • OM PRAKASH Department of PMR, SMS Medical College, Jaipur, Rajasthan, India.

DOI:

https://doi.org/10.22159/ajpcr.2023.v16i3.46707

Keywords:

Delayed cord clamping, Hematological parameters, Singleton pregnant women

Abstract

Objectives: Evaluation of the hematological parameter in newborn by delayed cord clamping at 60 s and at 180 s. Comparison of the improvement in hematological parameters, that is, hemoglobin and serum ferritin in newborn by both methods.

Methods: This was randomized, controlled, and comparative study conducted during April 2021 to February 2022 at the Department of Obstetrics and Gynaecology, SMS Medical College, Jaipur. The study included sample size of 60 cases (30 cases in each group). 60 cases were randomly allocated to either 60 s (Group A) or 180 s (Group B) groups of delayed cord clamping. The study included all singleton pregnant women >34 weeks of gestational age.

Results: Mean hemoglobin±standard deviation of neonate at birth for Group A was13.53±0.56 g/dL and for Group B it was 13.85±0.55 g/dL. Mean hemoglobin ± standard deviation at 6 month for Group A was 13.19±0.53 g/dL and for Group B was 13.53±0.55 g/dL. Mean serum ferritin±standard deviation of infant at for Group A was 12.46±0.45% and for Group B was 12.86±0.55%.

Conclusion: Neonatal hemoglobin and serum ferritin were significantly higher in180 s delayed cord clamping as compared to 60 s delayed cord clamping group.

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References

DC Dutta. Textbook of obstetrics.8th ed. Hiralal Konar; 2015. p. 44.

Sharma JB. Textbook of obstetrics.1st ed. Dr. Vipin Gupta; 2014. p. 35.

Konar H. In: Dutta DC, editor. Textbook of Obstetrics. 8th ed., Vol. 1. Netherlands: Elsevier; 2015. p. 44.

Linderkamp O. Placental transfusion: Determinants and effects. Clin Perinatol 1982;9:559-92. PMID 6761038

Hutton EK, Hassan ES. Late vs early clamping of the umbilical cord in full term neonates: Systematic review and meta-analysis of controlled trials. JAMA 2007;297:1241-52. doi: 10.1001/jama.297.11.1241, PMID 17374818

Katheria AC, Lakshminrusimha S, Rabe H, McAdams R, Mercer JS. Placental transfusion: A review. J Perinatol 2017;37:105-11. doi: 10.1038/jp.2016.151, PMID 27654493

Airey RJ, Farrar D, Dul L. Alternative positions for the baby at birth before clamping the umbilical cord. Cochrane Database Syst Rev 2010;2010:CD00755. doi: 10.1002/14651858.CD007555.pub2, PMID 20927760

Agarwal S, Jaiswal V, Singh D, Jaiswal P, Garg A, Upadhyay A. Randomized control trial showed that delayed cord clamping and milking resulted in no significant differences in iron stores and physical growth parameters at one year of age. Acta Paediatr 2016;105:e526-30. doi: 10.1111/apa.13559, PMID 27564579

Songthamwat M, Witsawapaisan P, Tanthawat S, Songthamwat S. Effect of delayed cord clamping at 30 seconds and 1 minute on neonatal hematocrit in term cesarean delivery: A randomized trial. Int J Womens Health 2020;12:481-6. doi: 10.2147/IJWH.S248709, PMID 32607000

Gupta R, Ramji S. Effect of delayed cord clamping on iron stores in infants born to anaemic mothers: A randomized controlled trial. Indian Pediatr 2002;39:130-5. PMID 11867842

Chaparro CM, Neufeld LM, Alavez GT, Cedillo RE, Dewey KG. Effect of timing of umbilical cord clamping on iron status in Mexican infants: A randomized controlled trail. Lancet 2006;367:1997-2004. doi: 10.1016/S0140-6736(06)68889-2, PMID 16782490

Published

07-03-2023

How to Cite

PILANIA, P., U. MAHALA, and O. PRAKASH. “TO STUDY THE EFFECTS OF DIFFERENT TIMING OF DELAYED CORD CLAMPING ALONG WITH MILKING ON HAEMATOLOGICAL PARAMETERS IN NEWBORNS - A RANDOMIZED CONTROL TRIAL”. Asian Journal of Pharmaceutical and Clinical Research, vol. 16, no. 3, Mar. 2023, pp. 99-101, doi:10.22159/ajpcr.2023.v16i3.46707.

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