A CLINICAL STUDY OF TEAR FUNCTIONS IN PATIENTS WITH PINGUECULA BEFORE AND AFTER MEDICAL MANAGEMENT

BIMALESH OJHA; PANKAJ KATARIA; PANKAJ CHOUDHARY; POOJA SINGH

doi:10.22159/ajpcr.2022.v15i12.46793

Authors

BIMALESH OJHA Department of Ophthalmology, Shyam Shah Medical College, Rewa, Madhya Pradesh, India.
PANKAJ KATARIA Department of Ophthalmology, Shyam Shah Medical College, Rewa, Madhya Pradesh, India.
PANKAJ CHOUDHARY Department of Ophthalmology, Shyam Shah Medical College, Rewa, Madhya Pradesh, India.
POOJA SINGH Department of Ophthalmology, Shyam Shah Medical College, Rewa, Madhya Pradesh, India.

DOI:

https://doi.org/10.22159/ajpcr.2022.v15i12.46793

Abstract

Purpose: The purpose of the study was to determine the changes in tear functions after medical management of pinguecula.

Methods: This interventional prospective study included 70 patients with pinguecula random eyes; 39 males and 31 females, 17–70 years of age (mean±SD: 46.52±16.31 years) for medical management. They were categorized as grade P (0), P (1), and P (2) by slit lamp biomicroscopy.

Results: On the basis of statistical analysis applying unpaired t-test, for both the test parameters in P (0) grade of pinguecula patients, the p-values for mean Schirmer-1 test and Tear film break-up time (TFBUT) were 0.93, 0.46, 0.03, and 0.22, 0.002, and <0.0001 for BMM versus AMM at 1 m, 3 m, and 6 m, respectively. These p-values show that there were no significant changes in ST-1 at 1 m and 3 m follow-up after medical management. For TFBUT, p-values show that there were no significant changes at 1 m of follow-up but extremely significant at 3 m and 6 m of follow-up. For P (1) grade of pinguecula patients, the p-values for mean Schirmer-1 test and TFBUT were 0.81, 0.08, 0.0002, and 0.31, <0.0001 and <0.0001 for BMM versus AMM at 1 m, 3 m, and 6 m, respectively. These p-values show that there were no significant changes in ST-1 and TFBUT at 1m follow-up after medical management. While, extremely significant changes at 3 m and 6 m of follow-up in ST-1 as well as TFBUT both.

Conclusion: The alteration in schirmer-1 test and TFBUT after medical management with e/d carboxyl methyl cellulose 0.5% and/or e/d fluorometholone 0.1% shows improvement in tear film production and tear film stability after 6 months of follow-up.

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