CLINICAL PROFILE OF CHILDREN WITH FEBRILE SEIZURE IN A TEACHING HOSPITAL

Authors

DOI:

https://doi.org/10.22159/ajpcr.2023.v16i5.47106

Keywords:

CFS-Complex febrile seizure, FS-Febrile seizures, WBC-White blood cells

Abstract

Objectives: To find out the clinical feature and outcomes of febrile seizures.

Methods: After written informed consent, detailed clinical history of each patient including a time of presentation, the onset of fever and associated symptoms, data regarding demographic details, duration and type of seizure, history of seizures, and antiepileptic drug, repetition of seizure within 24 h, past history of seizures, birth history, family history was taken and entered in predesigned pro forma. Collected data were checked and verified for correctness and accuracy, which was then analyzed using statistical methods.

Results: In the present study male-to-female ratio was 1.75:1. The maximum number (82.5%) of patients lacked a family history of febrile seizure, while 17.5% of patients had a positive family history of FS. 70% of the pediatric patients had upper respiratory tract infection. The maximum number of patients had simple febrile seizures, which are 81.25%, whereas 18.75% of patients had complex febrile seizures. The majority (73.75%) of patients in the present study had anemia. WBC count >11×109/L was found in 45 patients out of 80 (56.25%), and WBC count<4.5×109/L was found in 6 out of 80 (7.5%).

Conclusion: Majority of patients with febrile seizures presented at a younger age which might represent the vulnerability of the developing brain to fever. As all the patients were discharged without any complication, so this study further adds to the knowledge of the benign nature of this disease.

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References

Byeon JH, Kim GH, Eun BL. Prevalence, incidence, and recurrence of febrile seizures in Korean children based on national registry data. J Clin Neurol 2018;14:43-7. doi: 10.3988/jcn.2018.14.1.43. PMID: 29629539; PMCID: PMC5765255

Freeman JM. Febrile seizures: A consensus of their significance, evaluation, and treatment. Pediatrics 1980;66:1009. PMID: 7454463

Chungath M, Shorvon S. The mortality and morbidity of febrile seizures. Nat Clin Pract Neurol 2008;4:610-21. doi: 10.1038/ncpneuro0922. PMID: 18978801

Guidelines for the management of convulsions with fever. Joint Working Group of the Research Unit of the Royal College of Physicians and the British Paediatric Association. BMJ 1991;303:634-6. doi: 10.1136/ bmj.303.6803.634. PMID: 1932910; PMCID: PMC1671115

Singhi PD, Jayshree K. Febrile seizures: An update. Indian Pediatr 1995;32:564-72. PMID: 8613315

Berg AT, Shinnar S. Complex febrile seizures. Epilepsia 1996;37:126-33. doi: 10.1111/j.1528-1157.1996.tb00003.x. PMID: 8635422

Joshi C, Wawrykow T, Patrick J, Prasad A. Do clinical variables predict an abnormal EEG in patients with complex febrile seizures? Seizure 2005;14:429-34. doi: 10.1016/j.seizure.2005.07.006. PMID: 16099180

Mikati MA, Hani AJ. Febrile seizures. In: Nelson Text Book of Pediatrics. 20th ed. Philadelphia, PA: Elsevier; 2015. p. 2829-31.

Van Stuijvenberg M, de Vos S, Tjiang GC, Steyerberg EW, Derksen- Lubsen G, Moll HA. Parents’ fear regarding fever and febrile seizures. Acta Paediatr 1999;88:618-22. doi: 10.1080/08035259950169260. PMID: 10419245

Kürügöl NZ, Tütüncüoglu S, Tekgül H. The family attitudes towards febrile convulsions. Indian J Pediatr 1995;62:69-75. doi: 10.1007/ BF02752187. PMID: 10829846

Parmar RC, Sahu DR, Bavdekar SB. Knowledge, attitude and practices of parents of children with febrile convulsion. J Postgrad Med 2001;47:19-23. PMID: 11590285

Amrendra. Clinical study of febrile convulsion. Karnataka Ped J 1997;16:11-5.

Shrestha D, Dhakal AK, Shakya H, Shakya A, Shah SC, Mehata S. Clinical characteristics of children with febrile seizure. J Nepal Health Res Counc 2014;12:162-6. PMID: 26032052

Raju V, Parvathy M. Clinical profile of children with febrile seizure in a peripheral teaching hospital. Int J Contemp Pediatr 2020;7:631-4. https://dx.doi.org/10.18203/2349-3291.ijcp20200528

Anderson AB, Desisto MJ, Marshall PC, Dewitt TG. Duration of fever prior to onset of a simple febrile seizure: A predictor of significant illness and neurologic course. Pediatr Emerg Care 1989;5:12-5. doi: 10.1097/00006565-198903000-00004. PMID: 2710662

Aliabad GM, Khajeh A, Fayyazi A, Safdari L. Clinical, epidemiological and laboratory characteristics of patients with febrile convulsion. J Compr Ped 2013;3:134-7.

Jang HN, Yoon HS, Lee EH. Prospective case control study of iron deficiency and the risk of febrile seizures in children in South Korea. BMC Pediatr 2019;19:309. doi: 10.1186/s12887-019-1675-4. PMID: 31484495; PMCID: PMC6724315

Biyani G, Ray SK, Chatterjee K, Sen S, Mandal PK, Mukherjee M. Leukocyte count and C reactive protein as diagnostic factors in febrile convulsion. Asian J Med Sci 2017;8:56-8. https://doi.org/10.3126/ajms. v8i2.1633

Published

07-05-2023

How to Cite

PRIYANISHABEN, D., Z. KHAN, and P. patil. “CLINICAL PROFILE OF CHILDREN WITH FEBRILE SEIZURE IN A TEACHING HOSPITAL”. Asian Journal of Pharmaceutical and Clinical Research, vol. 16, no. 5, May 2023, pp. 206-8, doi:10.22159/ajpcr.2023.v16i5.47106.

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