PREVALENCE OF URINARY TRACT INFECTIONS AMONG FEMALES OF REPRODUCTIVE AGE GROUP IN TERTIARY CARE TEACHING HOSPITAL

PRASAD RAO M; SREEDEVI K; SRIKANTH A; DIVYA DHARSHINI B

doi:10.22159/ajpcr.2023v16i9.47816

Authors

PRASAD RAO M Department of General Surgery, NRI Institute of Medical Sciences and Anil Neerukonda Hospital, Visakhapatnam, Andhra Pradesh, India.
SREEDEVI K Department of General Medicine, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India
SRIKANTH A Department of General Medicine, NRI Institute of Medical Sciences and Anil Neerukonda Hospital, Visakhapatnam, Andhra Pradesh, India.
DIVYA DHARSHINI B Department of Biochemistry, Government Medical College, Khammam-507002, India.

DOI:

https://doi.org/10.22159/ajpcr.2023v16i9.47816

Keywords:

Urinary tract infection, Escherichia coli, Dysuria, RCSB

Abstract

Objective: The purpose of the current study is to isolate, characterize, and evaluate the antibiotic susceptibility profile of the pathogenic bacteria causing urinary tract infections (UTIs) in females of reproductive age.

Methods: This is a cross-sectional descriptive study carried out in a Tertiary care teaching hospital for 1 year. A total of 100 urine samples from female patients in the reproductive age range of 15–44 years constitute the study’s sample size. Clean catch midstream urine samples were taken in sterile containers and inoculated on a different culture medium, such as cysteine, lactose, and electrolyte-deficient agar, to isolate the UTI pathogen. MacConkey agar was inoculated in parallel to target the growth of Gram-negative bacilli. Thereafter, using the common microbiological procedures, all positive cultures with significant bacteriuria were identified at the species level based on the colony features, Gram-staining reaction, and pattern of biochemical profiles. To investigate the pattern of antibiotic susceptibility, the disc diffusion method was used.

Results: Among the 100 study cases, the prevalence of UTI was seen in 38% of individuals and UTI was absent in 62% of individuals. Among the females (38% cases) who had UTI, 81% had symptomatic UTI and 19% had asymptomatic UTI. Among the 81% symptomatic individuals of UTI, all they showed burning micturition followed by 74% of individuals showed dysuria Among the uropathogens isolated, majority were Escherichia coli (40.7%) followed by CONS (22.3%) Majority of the E. coli isolates showed sensitivity to piperacillin/tazobactam and nitrofurantoin.

Conclusion: If left untreated, UTI is a significant public health issue. Early detection and timely treatment will lower the risk of developing further UTI complications, as well as the patient’s pain, length of stay in the hospital, and economic loss.

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References

Ana L. Flores-Mireles, Jennifer N. Walker. Urinary tract infections: epidemiology, mechanisms of infection and treatment options. Nat Rev Microbiol. 2015;13(5):269– 284.

Singh Randhir K, Dewasy Bijoylakshmi. Prevalence of antibiotic sensitivity pattern of uropathogens in patients of different age-groups from western region of Nepal. International Journal of Medical Research & Health Sciences. 2016;5(9):1-7.

Weekes LM. Antibiotic resistance changing management of urinary tract infections in aged care. Med J Aust. 2015;203(9):352.

Emiru T, et al. Associated risk factors of urinary tract infection among pregnant women at Felege Hiwot referral hospital, Bahir Dar, north West Ethiopia. BMC Research Notes. 2013;6(1):292.

Wolday D, Erge W. Increased incidence of resistance to antimicrobials by urinary pathogens isolated at Tikur Anbessa hospital. Ethiop Med J. 1997;35(2):127–35.

Shaifali I, Gupta U, Mahmood SE, Ahmed J. Antibiotic susceptibility patterns of urinary pathogens in female outpatients. North Am JMed Sci. 2012;4(4):163.27.

Subhashini N, Joby J, Latha A, Indira A. Assess the prevalence of urinary tract infection among patients admitted in tertiary care hospital at Nellore. Indian J Applied Res. 2016;2(6):865-6.28.

Hooton TM, Scholes D, Hughes JP, Winter C, Roberts PL, Stapleton AE, et al. A prospective study of risk factors for symptomatic urinary tract infection in young women. N Engl J Med. 1996;335(7):468-74.

Muthulakshmi M, Gopalakrishnan S.Study on urinary tract infection among females of reproductive age group in a rural area of Kancheepuram district, Tamil Nadu. Int J Community Med Public Health2017;4:3915-21.

Kayima JK, Otieno LS, Twahir A et al. Asymptomatic bacteriuria among diabetics attending Kenyatta National Hospital. East Afr. Med. 1996;73(8):524–526.

Moges AF, Genetu A, Mengistu G. Antibiotic sensitivities of common bacterial pathogens in urinary tract infections in Gondar Hospital, Ethiopia. East African Medical Journal. 2002;79(3):140–142.

Wanyama J. Prevalence, bacteriology and microbial sensitivity patterns among pregnant women with clinically diagnosed urinary tract infections in Mulago Hospital Labour Ward. Makerere University, Kampala, Uganda, 2003. M.Ed. dissertation of Wanyama.

Saeed S, Tariq P. Symptomatic and asymptomatic urinary tract infections during pregnancy. Int J Microbiol Res 2011; 2(2): 101-4.

Hamdan HZ, Ziad AH, Ali SK, Adam I. Epidemiology of urinary tract infections and antibiotics sensitivity among pregnant women at Khartoum North Hospital. Ann Clin Microbiol Antimicrob. 2011 Jan 18;10:2.

Chandel LR, Kanga A, Thakur K, Mokta KK, Sood A, Chauhan S. Prevalance of pregnancy associated asymptomatic bacteriuria: a stud

y done in a tertiary care hospital. J Obstet Gynaecol India. 2012 Oct;62(5):511-4.Jain V, Das V, Agarwal A, Pandey A. Asymptomatic bacteriuria & obstetric outcome following treatment in early versus late pregnancy in north Indian women. Indian J Med Res. 2013 Apr;137(4):753-8.