CLINICOPATHOLOGICAL STUDY OF UTERINE LEIOMYOMA WITH VARIOUS ASSOCIATED PATHOLOGIES IN A TERITIARY CARE CENTER.
DOI:
https://doi.org/10.22159/ajpcr.2023.v16i12.48395Keywords:
Uterine leiomyoma, Hysterectomy, Pathological changesAbstract
Objectives: The present study was conducted to find the clinicopathological features of uterine leiomyoma seen in hysterectomy and myomectomy specimens.
Methods: A 2-year retrospective study was done from January 2021 to December 2022 at Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar. 100 patients diagnosed with leiomyoma on histopathological examination of hysterectomy specimens were included in the study.
Results: Uterine leiomyoma was most common in women in the age group of 41–50 years (80%) and presented with abdominal pain (60%). The most common location was intramural (40%), and the most common degeneration was a hyaline change (18%).
Conclusion: The benign tumor of smooth muscle, uterine leiomyoma, is commonly seen in perimenopausal females. Leiomyoma is associated with various pathologies, comprising degenerative changes and coexisting benign and malignant lesions. Hence, histopathological examination should be done to identify the spectrum of uterine leiomyoma and associated pathologies.
Downloads
References
Gull B, Karlsson B, Milsom I, Granberg S. Factors associated with endometrial thickness and uterine size in random sample of postmenopausal women. Am J Obstet Gynecol 2001;185:386-91. doi: 10.1067/mob.2001.115869, PMID 11518897
Crum CP. Body of uterus and endometrium. In: Kumar V, Abbas AK, Fausto N, editors. Robbins and Cotran Pathologic Basis of Disease. 7th ed. Philadelphia, PA: Saunders; 2004. p. 1089-90.
Nivethithai P, Nikhat SR, Rajesh BV. Uterine fibroids: A review. Indian J Pharm Pract 2010;3:6-11.
Zaloudek CJ, Hendrickson MR, Soslow RA. Mesenchymal tumors of uterus. In: Blaustein Pathology of the female genital tract. 6th ed. Germany: Springer Science; 2011. p. 459-66.
Nausheen F, Iqbal J, Bhatti FA, Khan AT, Sheikh S. Hysterectomy: The patient’s perspective. Ann Gynecol 2004;10:339-41.
Subrata P, Srabani C, Anuradha S, Prakash PJ, Kingshuk B, Mrinal S. A retrospective clinic-pathological study of hysterectomy cases in a tertiary care hospital in India-a review of 950 cases. Bangladesh J Med Sci 2018;17:88-92. doi: 10.3329/bjms.v17i1.35287
Gupta G, Kotasthane D, Kotasthane V. Hysterectomy: A clinic-pathological correlation of 500 cases. Int J Gynecol Obstet 2009;14.
Rather GM, Gupta Y, Bardhwaj S. Patterns of lesions in hysterectomy specimens: A prospective study. JK Sci 2013;15:35-8.
Gowri M, Mala G, Murthy S, Nayak V. Clinico-pathological study of uterine leiomyomas in hysterectomy specimens. J Evol Med Dent Sci 2013;2:9002-9. doi: 10.14260/jemds/1563
Bhatta S, Bhandari S, Osti BP. Histopathological study of uterine leiomyoma in hysterectomy specimens. Ann Clin Chem Lab Med 2017;3:16-20. doi: 10.3126/acclm.v3i2.20739
Manjula K, Rao KS, Chandrasekhar HR. Variants of leiomyoma: Histomorphological study of tumors of myometrium. J S Asian Fed Obstet Gynecol 2011;3:89-92. doi: 10.5005/jp-journals-10006-1137
Lahori M, Anita SM, Sakul AK, Goswami KC. Clinicopathological spectrum of uterine leiomyomas in a state of Northern India: A hospital based study. Int J Reprod Contracept Obstet Gynecol 2016;5:2295-99.
Karthikeyan TM, Veena NN, Kumar CR, Thomas E. Clinicopathological study of hysterectomy among rural patients in a tertiary care center. IOSR J Dent Med Sci 2015;14:25-7.
Jalandhara J, Mehta K, Desai R, Parakh P, Choudhary G. Clinicopathological study of uterine leiomyomas-a multicentric study in rural population. Int J Med Health Res 2018;4:16-8.
Kaur H, Gulati A. Pathophysiology of fibroids. Indian J Pathol Oncol 2014;1:14-7.
Published
How to Cite
Issue
Section
Copyright (c) 2023 RAJITHA JILLA
This work is licensed under a Creative Commons Attribution 4.0 International License.
The publication is licensed under CC By and is open access. Copyright is with author and allowed to retain publishing rights without restrictions.
